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Plant Genetics   Research Article

Overexpression of the activated form of the AtAREB1 gene (AtAREB1Ã?Â?QT) improves soybean responses to water deficit

Authors: J.P. Leite, E.G.G. Barbosa, S.R.R. Marin, J.P. Marinho, J.F.C. Carvalho, R.F. Pagliarini, A.S. Cruz, M.C.N. Oliveira, J.R.B. Farias, N. Neumaier, F.C.M. Guimar�£es, T. Yoshida, N. Kanamori, Y. Fujita, K. Nakashima, K.Y. Shinozaki, J.A. Desid�©rio and A.L. Nepomuceno

Abscisic acid-responsive element binding protein (AREB1) is a basic domain/leucine zipper transcription factor that binds to the abscisic acid (ABA)-responsive element motif in the promoter region of ABA-inducible genes. Because AREB1 is not sufficient to direct the expression of downstream genes under non-stress conditions, a.. Read More»

Genet. Mol. Res. 13(3):
2014.August.15.10
DOI:
10.4238/2014.August.15.10
Medical Genetics   Research Article

Modulation of expressivity in PDGFRB-related infantile myofibromatosis: a role for PTPRG?

Authors: N.D. Linhares, M.C.M. Freire, R.G.C.C.L. Cardenas, M. Bahia, E. Puzenat, F. Aubin and S.D.J. Pena

Infantile myofibromatosis is a rare genetic disorder characterized by the development of benign tumors in the skin, muscle, bone, and viscera. The molecular pathogenesis is still incompletely known. An autosomal dominant form had been reported as causally related with mutations in the gene for platelet-derived growth factor re.. Read More»

Genet. Mol. Res. 13(3):
2014.August.15.11
DOI:
10.4238/2014.August.15.11
Human Genetics   Research Article

Surgical management of biliary cystadenoma and cystadenocarcinoma of the liver

Authors: Y.W. Chen, C.H. Li, Z. Liu, J.H. Dong, W.Z. Zhang and K. Jiang

Biliary cystadenoma (BCA) and biliary cystadenocar­cinoma (BCAC) are rare biliary duct neoplasms. This study investi­gated reasonable management strategies of cystic neoplasms in the liver. Charts of 39 BCA/BCAC patients (9 males, 30 female; median age 53.74 ± 14.50 years) who underwent surgery from January 1999.. Read More»

Genet. Mol. Res. 13(3):
2014.August.25.1
DOI:
10.4238/2014.August.25.1
Plant Genetics   Research Article

Differential interactions between Curtobacterium flaccumfaciens pv. flaccumfaciens and common bean

Authors: S.C.D. Valdo, A. Wendland, L.G. Ara�ºjo, L.C. Melo, H.S. Pereira, P.G. Melo and L.C. Faria

Bacterial wilt of common bean caused by Curtobacterium flaccumfaciens pv. flaccumfaciens is an important disease in terms of economic importance. It reduces grain yield by colonizing xylem vessels, subsequently impeding the translocation of water and nutrients to the superior plant parts. The existence of physiological races i.. Read More»

Genet. Mol. Res. 15(4):
gmr15048712
DOI:
10.4238/gmr15048712
Medical Genetics   Research Article

Cox-2 gene polymorphism and IL-6 levels in coronary artery disease

Authors: K.K. Ol, B. Agachan, U. Gormus2, B. Toptas and T. Isbir

Coronary artery disease is one of the leading causes of mortality and diabetes mellitus is one of its main risk factors due to microvascular and macrovascular complications, such as atherosclerosis. Atherosclerosis is now known to be an inflammatory process mediated by prostaglandins and several interleukins. As both are impor.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr967
DOI:
10.4238/vol10-2gmr967
Plant Genetics   Research Article

Genetic variation and comparison of orchardgrass (Dactylis glomerata L.) cultivars and wild accessions as revealed by SSR markers

Authors: W.G. Xie, X.F. Lu, X.Q. Zhang, L.K. Huang and L. Cheng

Orchardgrass is a highly variable, perennial forage grass that is cultivated throughout temperate and subtropical regions of the world. Despite its economic importance, the genetic relationship and distance among and within cultivars are largely unknown but would be of great interest for breeding programs. We investigated the .. Read More»

Genet. Mol. Res. 11(1):
2012.February.24.1
DOI:
10.4238/2012.February.24.1
Human Genetics   Research Article

Ala-9Val polymorphism of Mn-SOD gene in sickle cell anemia

Authors: S. Sogut, Z. Yonden, H. Kaya, S. Oktar, M. Tutanc, H.R. Yilmaz, A. Yigit, N. Ozcelik and E. Gali

Oxidative stress may be contributory to the pathophysiology of the abnormalities that underlie the clinical course of sickle cell anemia. We looked for a possible genetic association between the functional polymorphism Ala-9Val in the human Mn-SOD gene and sickle cell anemia. One hundred and twenty-seven patients with sickle c.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1106
DOI:
10.4238/vol10-2gmr1106
Human Genetics   Research Article

Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer

Authors: J. Lin, R.M. Zeng, R.N. Li and W.H. Cao

Epidemiological studies have indicated that folate metabolism is correlated with increased risk of gastric cancer. Since methylenetetrahydrofolate reductase (MTHFR) is an important enzyme involved in folate metabolism, in this study, we examined whether polymorphisms and haplotypes of MTHFR are correlated with the risk of gast.. Read More»

Genet. Mol. Res. 13(1):
2014.March.24.10
DOI:
10.4238/2014.March.24.10
Microbial Genetics   Research Article

Molecular cloning of HSP70 in Mycoplasma ovipneumoniae and comparison with that of other mycoplasmas

Authors: M. Li, C.J. Ma, X.M. Liu, D. Zhao, Q.C. Xu and Y.J. Wang

Mycoplasma ovipneumoniae, a bacterial species that specifically affects ovine and goat, is the cause of ovine infectious pleuropneumonia. We cloned, sequenced and analyzed heat shock protein 70 (HSP70) (dnaK) gene of M. ovipneumoniae. The full length open reading frame of the M. ovipneumoniae HSP70 gene consists of 1812 nucleo.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1193
DOI:
10.4238/vol10-2gmr1193
Animal Genetics   Research Article

Identification and characterization of differentially expressed genes during incompatible interaction between the foliar rust Melampsora larici-populina and poplar

Authors: Z.J. Chen, Z.M. Cao and Z.D. Yu

Poplars are extensively cultivated worldwide, and their susceptibility to the foliar rust fungus leads to considerable damages in plantations. To better understand the molecular basis of poplar responses to the foliar rust, suppression subtractive hybridization was used to identify the potential important or novel genes involv.. Read More»

Genet. Mol. Res. 13(1):
2014.March.24.12
DOI:
10.4238/2014.March.24.12