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Sperm retrieval from patients with nonmosaic Klinefelter�s syndrome by semen cytologyexamination
Authors: Y.-T. Jiang, Y. Dong, X.-W. Yu, R.-C. Du, L.-L. Li, H.-G. Zhang and R.-Z. Liu
Successful sperm retrieval from ejaculates of nonmosaic Klinefelter’s syndrome (KS) patients by using semen cytology examination was described in this report. The clinical parameters of KS patients with sperm compared to patients without sperm were described. One hundred and fifty-one patients were proven to suffer from .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.12
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.12
Apolipoprotein E polymorphism in elderly Japanese-Brazilian immigrants does not explain the reduced cardiovascular risk factor incidence
Authors: N. Terra, Y. Moriguchi, L. Bittencourt, R.S. Trois, J.E.C. Piccoli and I.B.M. Cruz
Study of immigrant populations may contribute to a better understanding of the epidemiology of diseases associated with the aging process. We examined the prevalence of cardiovascular risk factors, including apolipoprotein E (ApoE) polymorphism, in elderly subjects who were born in Japan, migrated to South Brazil and have live.. Read More»
- Genet. Mol. Res. 10(3):
From unicellularity to multicellularity - molecular speculations about early animal evolution
Authors: H.F. Hoenigsberg, M.H. TÃ?Âjaro and C. Sanabria
A morphological, physiological, developmental, and genetic organization of great complexity ineluctably unfolded from relatively simple phenomena invested with enormous potential. Sometime long ago in the Protererozoic times, parasitic invasions caused lower evolutionary levels to integrate into higher-level selection. Therefore, we have a multi-level sel.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr375
- DOI:
- 10.4238/vol7-1gmr375
Diallel analysis to choose parents for black bean (Phaseolus vulgaris L.) breeding
Authors: L.M. Moura, P.C.S. Carneiro, N.M. Vale, L.D. Barili, L.C. Silva, J.E.S. Carneiro and C.D. Cruz
In this study, conducted in two different seasons, we aimed to choose parents to obtain promising segregating populations for the extraction of black bean (Phaseolus vulgaris L.) lines that are superior in terms of disease resistance, plant architecture, and grain yield. Twelve parents were arranged in two groups to compose a .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038574
- DOI:
- 10.4238/gmr.15038574
Novel representation of RNA secondary structure used to improve prediction algorithms
Authors: Q. Zou, C. Lin, X.-Y. Liu, Y.-P. Han, W.-B. Li and M.-Z. Guo
We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the comparative sequence analysis method results and the min.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1181
- DOI:
- 10.4238/vol10-3gmr1181
Screening of differentially expressed genes between multiple trauma patients with and without sepsis
Authors: S.C. Ji, Y.T. Pan, Q.Y. Lu, Z.Y. Sun and Y.Z. Liu
The purpose of this study was to identify critical genes associated with septic multiple trauma by comparing peripheral whole blood samples from multiple trauma patients with and without sepsis. A microarray data set was downloaded from the Gene Expression Omnibus (GEO) database. This data set included 70 samples, 36 from mult.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.13
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.13
Rapid and inexpensive analysis of genetic variability in Arapaima gigas by PCR multiplex panel of eight microsatellites
Authors: I.G. Hamoy, E.J.M. Santos and S.E.B. Santos
The aim of the present study was the development of a multiplex genotyping panel of eight microsatellite markers of Arapaima gigas, previously described. Specific primer pairs were developed, each one of them marked with either FAM-6, HEX or NED. The amplification conditions using the new primers were standardized for a single reaction. The results obtain.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr394
- DOI:
- 10.4238/vol7-1gmr394
A/G Gln20Arg (exon 1) and G/A Val156Met (exon 5) polymorphisms of the human orosomucoid 1 gene in Mexico
Authors: L. GarcÃ?Âa-Ortiz, G. Vargas-AlarcÃ?³n, J.M. Fragoso, J. Granados, L. Maldonado Noriega, A. Navas PÃ?©rez , E. Huerta Reyes, J.C. Zenteno-Ruiz and E. MartÃ?Ânez-Cordero
The human orosomucoid 1 gene (ORM1) codes an alpha-1-acid glycoprotein that has been classified as an acute-phase reactive protein, and a major drug-binding serum component, as well as an immunomodulatory protein with genetic polymorphisms. Evaluation of ORM variation through isoelectric focusing and immunobloting has revealed a world-wide distribution of.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr348
- DOI:
- 10.4238/vol7-1gmr348
Response to treatment with imatinib mesylate in previously treated chronic-phase chronic myeloid leukemia patients in a hospital in Brazil
Authors: C.A.P. Silveira, M.B. Daldegan and I. Ferrari
We analyzed the results of treatment with imatinib mesylate in 70 patients with chronic-phase chronic myeloid leukemia who had previously been treated (with second-line or higher imatinib), many of them in a late chronic phase. The median follow-up period was 60.5 months (range 3-100 months). Our objective was to assess the ef.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1073
- DOI:
- 10.4238/vol10-3gmr1073
Molecular basis for porcine parvovirus detection in dead fetuses
Authors: V.H.G. Wolf , M. Menossi, G.B. Mour�£o and M.S.V. Gatti
Reproductive failures are still common grounds for complaint by commercial swine producers. Porcine parvovirus (PPV) is associated with different clinical reproductive signs. The aim of the present study was to investigate PPV fetal infection at swine farms having ongoing reproductive performance problems. The presence of viru.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr440
- DOI:
- 10.4238/vol7-2gmr440