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Human Genetics   Research Article

New chromosomal evidence for the origin of Triatoma infestans populations from Brazil

Authors: N.P. Pereira, K.C.C. Alevi, J.A. Rosa and M.T.V. Azeredo-Oliveira

In this study, the karyometry of different Triatoma infestans populations from different states of Brazil was analyzed and compared with those of a population from Cochabamba. No significant differences were found between the population from Cochabamba and those from Brazil. These results are consistent with the origin of the T. infestans populations of B.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038303
DOI:
10.4238/gmr.15038303
Human Genetics   Research Article

Low levels of serum miR-99a is a predictor of poor prognosis in breast cancer

Authors: J. Li, Z.J. Song, Y.Y. Wang, Y. Yin, Y. Liu and X. Nan

MicroRNA (miRNA) deregulation has been previously linked to the initiation and development of breast cancer. Although miR-99a is aberrantly expressed in many types of cancers, including breast cancer, the serum miR-99a expression level in breast cancer and its clinical significance remains unknown. Blood samples were obtained from 72 patients with breast .. Read More»

Genet. Mol. Res. 15(3):
gmr.15038338
DOI:
10.4238/gmr.15038338
Human Genetics   Research Article

Investigation on ERCC5 genetic polymorphisms and the development of gastric cancer in a Chinese population

Authors: L.Q. Yang, Y. Zhang and H.F. Sun

Our study aimed to investigate the role of 2 ERCC5 promoter SNPs (rs2094258 and rs751402) in the development of gastric cancer in the Chinese population. The present hospital-based case-control study consisted of 155 patients with gastric cancer and 246 healthy controls recruited between March 2012 and December 2014. Genotyping for the rs2094258 and rs751.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038364
DOI:
10.4238/gmr.15038364
Medical Genetics   Research Article

Development and significance of SCAR marker QG12-5 for Canarium album (Lour.) Raeusch by molecular cloning from improved RAPD amplification

Authors: J.L. Cheng, Z.C. Yin Z.Q. Mei, C.L. Wei, H.C. Chen, X.S. Wu and J.J. Fu

Sequence-characterized amplified region (SCAR) is a valuable molecular marker for the genetic identification of any species.This marker is mainly derived from molecular cloning of random amplified polymorphic DNA (RAPD). We have previously reported the use of an improved RAPD technique for the genetic characterization of different samples of Canarium albu.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038347
DOI:
10.4238/gmr.15038347
Microbial Genetics   Research Article

Two chitin metabolic enzyme genes from Hyriopsis cumingii: cloning, characterization, and potential functions

Authors: G.-L. Wang B. Xu Z.-Y. Bai J.-L. Li

Chitin, the second most important natural polymer in the world, and its N-deacetylated derivative chitosan are found in a wide variety of organisms. These versatile biopolymers are associated with a broad range of biological functions. This article is the first to report the potential functions of 2 chitin metabolic enzyme gen.. Read More»

Genet. Mol. Res. 11(4):
2012.October.15.4
DOI:
10.4238/2012.October.15.4
Human Genetics   Research Article

TGF-?²1 polymorphisms and familial aggregation of liver cancer in Guangxi, China

Authors: P.Q. Wan, J.Z. Wu, L.Y. Huang, J.L. Wu, Y.H. Wei and Q.Y. Ning

The goal of present study was to investigate the relationship between polymorphisms of TGF-β1 and familial aggregation of liver cancer in Guangxi Zhuang, Han, and Yao populations. We conducted a population-based case-control family study of liver cancer in Guanxi, China. A total of 214 individuals from 37 case families were surveyed for polymorphisms.. Read More»

Genet. Mol. Res. 14(3):
2015.July.27.3
DOI:
10.4238/2015.July.27.3
Microbial Genetics   Research Article

Genetic diversity of ITS sequences of Bursaphelenchus xylophilus

Authors: J.M.S. Cardoso L. Fonseca I. Abrantes

The sequence variation of internal transcribed spacer (ITS) regions of ribosomal DNA has been routinely used for species identification and species-level phylogeny of the pinewood nematode, Bursaphelenchus xylophilus. In this study, the intraspecies ITS genetic diversity of B. xylophilus was evaluated. Three pinewood nematode isolates from the United Stat.. Read More»

Genet. Mol. Res. 11(4):
2012.October.15.1
DOI:
10.4238/2012.October.15.1
Human Genetics   Research Article

Immunomodulatory and clinical effects of the â??tiaomian III decoctionâ? in patients with blood blocking antibody deficiency and recurrent spontaneous abortion

Authors: H.Y. Gao, E.X. Tao, Y. Wang, Q.A. Yue, C.E. Ren and L.F. Yan

We studied the immunomodulatory and clinical effects of the empirical formula “tiaomian III decoction” on maternal blood blocking antibody deficiency and recurrent spontaneous abortion. Sixty-one patients with blocking antibody deficiency were divided in the experimental group (N = 31), who took tiaomian III decoction, and the control group (N.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.15.5
DOI:
http://dx.doi.org/10.4238/2015.April.15.5
Human Genetics   Research Article

Sexual genetic and simple sequence repeat (SSR) analysis for molecular marker development on the all hermaphrodite papaya

Authors: C.T. Chiu, C.W. Wang, F.C. Chen, S.W. Chin, C.C. Liu, M.J. Lee, W.C. Chung, Y.W. Chien, H.J. Chang and C.Y. Lee

The papaya (Carica papaya L.) is one of the most important economic tropical fruits in the world, and the hermaphrodite is the preferred type in field cultures. We analyzed the sexual ratio of offspring from the cultivar ‘Taiwan Seed Station No. 7’ (T7) by a self-cross and its cross with Taichung Sunrise (TS). Female progeny from the T7 self-c.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.8
DOI:
http://dx.doi.org/10.4238/2015.March.30.8
Human Genetics   Research Article

Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at-onset of non-small cell lung cancer

Authors: W.X. Hu, C.M. Ding, R.J. Li, H.Y. Fan, Z.J. Guo and W. Liu

The associations between single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) and cancer risk and disease outcome have been extensively analyzed. We investigated the association between age-at-onset and SNPs in the mitochondrial D-loop using a population-based series of non-small cell lung cancer (NSCLC) pa.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.9
DOI:
http://dx.doi.org/10.4238/2015.March.30.9