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Polymorphisms of eNOS, catalase, and myeloperoxidase genes in prostate cancer in Turkish men: preliminary results
Authors: G.G. Ceylan, C. Ceylan, B. G�¼lmemmedo ��. Tonyal�±, O. Odaba�� A. G�¶zalan, �°. Kele�� and E. ��zt�¼rk
Prostate cancer (PCa) is the most common type of neoplasm in European males. Genetic and epigenetic factors contribute to PCa development and progression. In this study, we aimed to assess the relationship between PCa and polymorphisms in the genes encoding endothelial nitric oxide synthase (eNOS), catalase (CAT), and myeloperoxidase (MPO). In total, 193 .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038543
- DOI:
- 10.4238/gmr.15038543
Benchmark comparison of ab initio microRNA identification methods and software
Authors: L.L. Hu Y. Huang Q.C. Wang Q. Zou Y. Jiang
MicroRNAs (miRNAs) are short, non-coding RNA molecules that play an important role in the world of genes, especially in regulating the gene expression of target messenger RNAs through cleavage or translational repression of messenger RNA. Ab initio methods have become popular in computational miRNA detection. Most software tools are designed to distinguish m.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.17.4
- DOI:
- 10.4238/2012.October.17.4
mtDNA variation of the critically endangered hawksbill turtle (Eretmochelys imbricata) nesting on Iranian islands of the Persian Gulf
Authors: M. Tabib, H. Zolgharnein, M. Mohammadi, M.A. Salari-Aliabadi, A. Qasemi, S. Roshani, H. Rajabi-Maham and F. Frootan
Genetic diversity of sea turtles (hawksbill turtle) was studied using sequencing of mitochondrial DNA (mtDNA, D-loop region). Thirty dead embryos were collected from the Kish and Qeshm Islands in the Persian Gulf. Analysis of sequence variation over 890 bp of the mtDNA control region revealed five haplotypes among 30 individua.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1148
- DOI:
- 10.4238/vol10-3gmr1148
Structure and polymorphism of 16 novel Y-STRs in Chinese Han Population
Authors: G.Q. Zhang S.Y. Yang L.L. Niu D.W. Guo
Y-chromosome short tandem repeats (Y-STRs) are useful tools for identifying paternity origin and male-female mixed samples because of their male-specificity, haploid inheritance and relatively simplicity. We focused on novel Y-STRs deposited in the human Genome database from DYS708 to DYS726. We typed 16 male-specific Y-STRs from males of a Chinese Han popul.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.11.1
- DOI:
- 10.4238/2012.October.11.1
Heteroduplex formation and S1 digestion for mapping alternative splicing sites
Authors: E.N. Ferreira, M.C.R. Rangel, P.B. Pineda, D.O. Vidal, A.A. Camargo, S.J. Souza and D.M. Carraro
The identification of alternatively spliced transcripts has contributed to a better comprehension of developmental mechanisms, tissue-specific physiological processes and human diseases. Polymerase chain reaction amplification of alternatively spliced variants commonly leads to the formation of heteroduplexes as a result of ba.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting012
- DOI:
- 10.4238/vol7-3x-meeting012
Balanced reciprocal translocation at amniocentesis: cytogenetic detection and implications for genetic counseling
Authors: H.G. Zhang, X.Y. Zhang, H.Y. Zhang, T. Tian, S.B. Xu and R.Z. Liu
Balanced translocation is a common structural chromosomal rearrangement in humans. Carriers can be phenotypically normal but have an increased risk of pregnancy loss, fetal death, and the transmission of chromosomal abnormalities to their offspring. Existing prenatal screening technologies and diagnostic procedures fail to detect balanced translocation, s.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038556
- DOI:
- 10.4238/gmr.15038556
Testing the performance of automated annotation of ESTs with the Kegg Orthology (KO) database demonstrates lack of completeness of clusters
Authors: G.R. Fernandes, M.A. Mudado and J.M. Ortega
The KEGG Orthology (KO) database was tested as a source for automated annotation of expressed sequence tags (ESTs). We used a control experiment where every EST was assigned to its cognate protein, and an annotation experiment where the ESTs were annotated by proteins from other organisms. Analyzing the results, we could assig.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting011
- DOI:
- 10.4238/vol7-3x-meeting011
An algorithm to infer similarity among cell types and organisms by examining the most expressed sequences
Authors: S.A.P. Pinto and J.M. Ortega
Following sequence alignment, clustering algorithms are among the most utilized techniques in gene expression data analysis. Clustering gene expression patterns allows researchers to determine which gene expression patterns are alike and most likely to participate in the same biological process being investigated. Gene express.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting010
- DOI:
- 10.4238/vol7-3x-meeting010
Isolation and characterization of microsatellite loci in the fish Coilia mystus (Clupeiformes: Engraulidae) using PCR-based isolation of microsatellite arrays
Authors: J.-Q. Yang, X.-D. Zhou, D. Liu, Z.-Z. Liu and W.-Q. Tang
Coilia mystus is the most important harvested fish species in China; it inhabits quite different water environments during the different life history stages. Populations of C. mystus have dropped sharply due to overharvesting and water pollution. We developed eight microsatellite loci in C. mystus for conservation genetics stu.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1420
- DOI:
- 10.4238/vol10-3gmr1420
A procedure to recruit members to enlarge protein family databases - the building of UECOG (UniRef-Enriched COG Database) as a model
Authors: G.R. Fernandes, D.V.C. Barbosa, F. Prosdocimi, I.A. Pena,L. Santana-Santos, O. Coelho Junior, A. Barbosa-Silva, H.M. Velloso, M.A. Mudado, D.A. Natale, A.C. Faria-Campos, S.V. A. Campos and J.M. Ortega
A procedure to recruit members to enlarge protein family databases is described here. The procedure makes use of UniRef50 clusters produced by UniProt. Current family entries are used to recruit additional members based on the UniRef50 clusters to which they belong. Only those additional UniRef50 members that are not fragments.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting008
- DOI:
- 10.4238/vol7-3x-meeting008