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Expression and clinical significance of the obesity-related gene TNFAIP9 in obese children
Authors: L.Y. Gui, Y.L. Hu, Z.L. Hou and P. Wang
To investigate the expression of tumor necrosis factor-alpha inducible protein 9 (TNFAIP9) gene in obese children and its clinical significance, 36 simple obese children and 17 non-obese children were recruited as research subjects. The adipose tissue was obtained by abdominal operation. The expression of TNFAIP9 was detected using real-time fluorescence .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037995
- DOI:
- 10.4238/gmr.15037995
Sequence divergence of microsatellites for phylogeographic assessment of Moroccan Medicago species
Authors: N. Zitouna, S. Marghali, M. Gharbi, A. Haddioui and N. Trifi-Farah
Six Medicago species were investigated to characterize and valorize plant genetic resources of pastoral interest in Morocco. Samples were obtained from the core collection of the South Australian Research and Development Institute (SARDI). The transferability of single sequence repeat markers of Medicago truncatula was success.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.12.7
- DOI:
- http://dx.doi.org/10.4238/2014.March.12.7
De novo transcriptome analysis of tobacco seedlings and identification of the early response gene network under low-potassium stress
Authors: L.Q. Li, J. Li, Y. Chen, Y.F. Lu and L.M. Lu
Tobacco is an economically important crop, and its potassium content can greatly affect the quality of tobacco leaves. However, the molecular mechanism involved in potassium starvation in tobacco has not been elucidated to date. In this study, Illumina (Solexa) sequencing technology was used to analyze the transcriptome of tobacco seedlings under low-pota.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038599
- DOI:
- 10.4238/gmr.15038599
Development of coding single nucleotide polymorphic markers in the pearl oyster Pinctada fucata based on next-generation sequencing and high-resolution melting analysis
Authors: S.G. Fan, J.F. Wei, Y.H. Guo, G.J. Huang and D.H. Yu
The pearl oyster Pinctada fucata is an important commercial marine shellfish that is cultured for producing saltwater pearls. In this study, 468 single nucleotide polymorphisms (SNPs) were screened from P. fucata transcriptome data, and 119 polymorphic SNPs were successfully isolated by a two-step small-amplicon high-resolutio.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049054
- DOI:
- 10.4238/gmr15049054
Combined effect of traditional Chinese and Western medicine on inflammatory factors in patients with diabetes-induced xerophthalmia
Authors: S.Q. Wu, Q. Dai, J.L. Xu, W.Y. Sheng, Q.B. Xu and L.Y. Zhong
Diabetes-induced xerophthalmia is a general metabolic disorder with high incidence and increased treatment difficulty. Our study aimed to explore the combined effect of traditional Chinese and Western medicines on diabetes-associated xerophthalmia. We recruited 60 diabetic xerophthalmia patients, and randomly assigned them to .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049030
- DOI:
- 10.4238/gmr15049030
Novel visual system homeobox 1 gene mutations in Turkish patients with keratoconus
Authors: H. Bardak, M. Gunay, E. Yildiz, Y. Bardak, B. Gunay, H. Ozbas and O. Bagci
The aim of this study was to screen the visual system homeobox 1 (VSX1) gene in Turkish patients with keratoconus (KC). The patient group consisted of 44 patients who had undergone corneal transplant surgery before the age of 30, for advanced and rapidly progressive KC. The control group comprised 250 healthy individuals. We d.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049024
- DOI:
- 10.4238/gmr15049024
Rhizosphere bacteriome of the medicinal plant Sapindus saponaria L. revealed by pyrosequencing
Authors: A. Garcia, J.C. Polonio, A.D. Polli, C.M. Santos, S.A. Rhoden, M.C. Quecine, J.L. Azevedo and J.A. Pamphile
Sapindus saponaria L. of Sapindaceae family is popularly known as soldier soap and is found in Central and South America. A study of such medicinal plants might reveal a more complex diversity of microorganisms as compared to non-medicinal plants, considering their metabolic potential and the chemical communication between the.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049020
- DOI:
- 10.4238/gmr15049020
Cinnamon effectively inhibits the activity of leukemia stem cells
Authors: X. Guan, M.C. Su, R.B. Zhao, H.M. Ouyang, X.D. Dong, P. Hu, Q. Pei, J. Lu, Z.F. Li, C.R. Zhang and T.-H Yang
Cinnamon is the main component of Sanyangxuedai, which is one of the effective traditional Chinese medicines for treating malignancies. Leukemia is a prevalent malignant disease that Sanyangxuedai has been used to treat. Although successful in several studies, there is a lack of solid evidence as to why Sanyangxuedai has an effect on leukemia, and little .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037662
- DOI:
- 10.4238/gmr.15037662
Comparison of methods to preserve Rheum palmatum (Polygonaceae) for efficient DNA extraction and PCR amplification
Authors: M. Huang, X.J. Sun, Y. Zhou and X.M. Wang
In this study, we compared the quality of DNA extracted using the modified CTAB method, from Rheum palmatum leaves preserved using fourteen different methods, including ones used commonly in other species: under ultra-cold (-80°C) temperatures, after drying with an absorbent paper, desiccating using a silica gel, drying at 60°C, in 70% ethanol, ab.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038019
- DOI:
- 10.4238/gmr.15038019
Genetic diversity of Ceratoides arborescens, a species endemic to China, detected by intersimple sequence repeat (ISSR)
Authors: P.C. Wang, L.L. Zhao, B.T. Mo, Y. Zhang, J. Chen and L.B. Wang
In order to investigate genetic diversity and population structure of Ceratoides arborescens, six populations were selected from different steppe types in Inner Mongolia grasslands of China. Intersimple sequence repeat (ISSR) markers were used to assess the genetic diversity within and among natural populations of C. arborescens. Thirteen ISSR primers gen.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.18
- DOI:
- 10.4238/2015.May.25.18