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Association between IL-4 gene polymorphisms, IL-4 serum levels, and ankylosing spondylitis
Authors: X.L. Liu, J.K. Ren and Y.L. Su
We aimed to investigate the effect of two common polymorphisms in interleukin-4 (IL-4) on serum IL-4 levels and the development of ankylosing spondylitis (AS) in the Chinese population. A total of 420 inpatients and outpatients diagnosed with AS were enrolled as the case group, and 330 healthy volunteers were selected as the c.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048898
- DOI:
- 10.4238/gmr15048898
Genetic variability analysis of Byrsonima crassifolia germplasm collected in Par�¡ State using ISSR markers
Authors: S.M. Rodrigues, E.F. Moura, G.K.S. Ramos and M.S.P. Oliveira
Native of the Amazon, the nanche (Byrsonima crassifolia) is a fruit cultivated by family farmers and used in cooking; as such, it represents an opportunity for regional agribusiness. The Embrapa Eastern Amazon set up an active germplasm bank (BAG) consisting of 22 accessions sampled in 11 municipalities of Pará State. D.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048887
- DOI:
- 10.4238/gmr15048887
Genome-wide identification, classification, and analysis of heat shock transcription factor family in Chinese cabbage (Brassica rapa pekinensis)
Authors: X.Y. Huang, P. Tao, B.Y. Li, W.H. Wang, Z.C. Yue, J.L. Lei andX.M. Zhong
Chinese cabbage (Brassica rapa ssp. pekinensis) is one of the most important vegetable crops grown worldwide, and various methods exist for selection, propagation, and cultivation. The entire Chinese cabbage genome has been sequenced, and the heat shock transcription factor family (Hsfs) has been found to play a central role in plant growth and developmen.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.5
- DOI:
- 10.4238/2015.March.27.5
An exploratory survey of professionals on the use of stored tissue samples from minors for genetic research
Authors: K. Hens, J. Snoeck, H. Nys, J.-J. Cassiman and K. Dierickx
The ethical aspects of the use of stored tissue samples collected from minors are of topical interest. However, the views of professionals working in the field of genetics have not been investigated in depth anywhere. We conducted a survey among 194 such professionals in Belgium. This list was composed of the members of the Hi.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr781
- DOI:
- 10.4238/vol9-2gmr781
Characterization of a TIR-NBS-LRR gene associated with downy mildew resistance in grape
Authors: J.J. Fan, P. Wang, X. Xu, K. Liu, Y.Y. Ruan, Y.S. Zhu1, Z.H. Cui and L.J. Zhang
Grapevine downy mildew, caused by Plasmopara viticola, is a devastating disease that results in considerable economic losses as well as environmental damage through the repeated application of fungicides. The nucleotide-binding site leucine-rich repeat gene family functions in plant immunoactivity against various pathogens and pests. In this study, the 5'.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.4
- DOI:
- 10.4238/2015.July.17.4
Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation
Authors: A.D.B. Melo, H. Silveira, C. Bortoluzzi, L.J. Lara, C.A.P. Garbossa, G. Preis, L.B. Costa and M.H. Rostagno
In this study, we evaluated the effect of intestinal alkaline phosphatase (IAP) and sodium butyrate (NaBu) on lipopolysaccharide (LPS)-induced intestinal inflammation. Intestinal alkaline phosphatase and RelA/p65 (NF-κB) gene expressions in porcine jejunum explants were evaluated following exposure to sodium butyrate (Na.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048875
- DOI:
- 10.4238/gmr15048875
The Caenorhabditis elegans genome: a multifractal analysis
Authors: P.E. VÃ?©lez, L.E. Garreta, E. MartÃ?Ânez, N. DÃ?Âaz, S. Amador, I. Tischer, J.M. GutiÃ?©rrez and P.A. Moreno
The Caenorhabditis elegans genome has several regular and irregular characteristics in its nucleotide composition; these are observed within and between chromosomes. To study these particularities, we carried out a multifractal analysis, which requires a large number of exponents to characterize scaling properties. We looked f.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr756
- DOI:
- 10.4238/vol9-2gmr756
Case study of a patient presenting both type II bipolar affective disorder and Klinefelter syndrome
Authors: H. Delavenne, J.M. Khoury, F. Thibaut and F.D. Garcia
Klinefelter syndrome (KS) is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000. Increased incidences of anxiety, depression, substance abuse, psychotic and behavioral disorders, and sexual disorders have been reported in patients with KS. The aim of this case study was to report a case of a.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048872
- DOI:
- 10.4238/gmr15048872
A simple, fast, and inexpensive CTAB-PVP-silica based method for genomic DNA isolation from single, small insect larvae and pupae
Authors: W. Huanca-Mamani, D. Rivera-Cabello and J. Maita-Maita
In this study, we report a modified CTAB-PVP method combined with silicon dioxide (silica) treatment for the extraction of high quality genomic DNA from a single larva or pupa. This method efficiently obtains DNA from small specimens, which is difficult and challenging because of the small amount of starting tissue. Maceration with liquid nitrogen, phenol.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.8
- DOI:
- 10.4238/2015.July.17.8
Correlation of spicule sign on computed tomography scans with peripheral lung cancers associated with interstitial lung disease and chronic obstructive pulmonary disease
Authors: L. Chen, L. Gao and W.L. Wu
The objective of this study was to investigate the correlation between spicular signs on computed tomography (CT) scans and peripheral lung cancer (PLC) that is associated with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). We analyzed clinical data from 96 PLC cases and grouped patients based on whether they had interst.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.9
- DOI:
- 10.4238/2015.March.27.9