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A potential protective role for thiamine in glucose-driven oxidative stress
Authors: B. Palabiyik, F. Jafari Ghods and E. Onay Ucar
The relationship between glucose repression and the oxidative stress response was investigated in Schizosaccharomyces pombe wild type cells (972h-) and glucose repression resistant mutant type cells (ird11). We aimed to reveal the mechanism of simultaneous resistance to glucose repression and oxidati.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.13
- DOI:
- 10.4238/2014.July.25.13
A study on the relationship between TCTA tetranucleotide polymorphism of the HPRT gene and primary hyperuricemia
Authors: Y.S. Zhu, S.G. Wei, R.F. Sun, J.L. Feng, W.J. Kuang, J.H. Lai and S.B. Li
We examined polymorphism of the TCTA tetranucleotide sequence in the 3rd intron of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the Han population of Ningxia Province in China. We also looked for a possible relationship between STR polymorphism in the 3rd intron of the HPRT gene and primary hyperuricemia. .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.15.3
- DOI:
- 10.4238/2011.December.15.3
Evaluation of genotoxicity of Pseudevernia furfuracea (L.) Zopf by RAPD analysis
Authors: S. Aras, T. Beyazta��, D. Cansaran-Duman and E. G�¶k�§e-G�¼nd�¼zer
We investigated the suitability and applicability of Pseudevernia furfuracea (L.) Zopf for environmental genotoxicity assessment. P. furfuracea lichen specimens were collected from 10 different Pinus species, in every 5 km, starting from around an iron-steel factory located in the central area of Karabük Province up to Ye.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.15.4
- DOI:
- 10.4238/2011.December.15.4
Identification of complete linkage disequilibrium in the DSG4 gene and its association with wool length and crimp in Chinese indigenous sheep
Authors: Y.H. Ling, H. Xiang, G. Zhang, J.P. Ding, Z.J. Zhang, Y.H. Zhang, J.L. Han, Y.H. Ma and X.R. Zhang
The desmoglein 4 (DSG4) gene is a potential candidate in the search for genes that may affect wool traits, because of its function. This study aimed to screen for polymorphisms in partial exon 16 and 3êÂ?Â?UTR of the sheep desmoglein 4 DSG4 gene, and to test its possible association with wool length.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.17
- DOI:
- 10.4238/2014.July.25.17
Soybean rust resistance sources and inheritance in the common bean (Phaseolus vulgaris L.)
Authors: T.L.P.O. Souza, S.N. Dessaune, M.A. Moreira and E.G. Barros
Soybean rust (SBR), caused by the fungus Phakopsora pachyrhizi, has been reported in common bean (Phaseolus vulgaris L.) cultivars and elite lines that were infected under controlled and natural field conditions in South Africa, the United States, Argentina, and Brazil. Although SBR is currently not a top pri.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.18
- DOI:
- 10.4238/2014.July.25.18
Pulmonary hypertension in patients with stage 1-3 chronic kidney disease
Authors: Q.M. Yang and X.R. Bao
Pulmonary hypertension (PH) secondary to chronic kidney disease (CKD) is common, but in stages 1-3 CKD patients, it remains unclear. We sought to evaluate the prevalence of PH and elucidate the possible pathogenesis in Chinese patients with early stage kidney disease. Doppler-estimated pulmonary systolic artery pressure (PASP).. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.25
- DOI:
- 10.4238/2014.July.25.25
Outbreaks and genetic diversity of Francisella noatunensis subsp orientalis isolated from farm-raised Nile tilapia (Oreochromis niloticus) in Brazil
Authors: C.A.G. Leal, G.C. Tavares and H.C.P. Figueiredo
Francisella noatunensis subsp orientalis (FNO) is an emerging pathogen of warm water tilapia in a number of different countries. The disease caused by this bacterium in fish is characterized by a systemic granulomatous infection that causes high mortality rates during outbreaks. FNO has been previously described in As.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.26
- DOI:
- 10.4238/2014.July.25.26
Fibroin protein/chitosan scaffolds and bone marrow mesenchymal stem cells culture in vitro
Authors: J. Deng, R.F. She, W.L. Huang, C. Yuan and G. Mo
A previous experiment demonstrated that fibroin protein and chitosan mixed in proper proportion presented good physical and chemical properties and biological characteristics, which can make up for their respective disadvantages. To observe the growth of bone marrow mesenchymal stem cells (BMSCs) on these fibroin protein/chito.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.29.1
- DOI:
- 10.4238/2014.July.29.1
Sulcus vocalis: evidence for autosomal dominant inheritance
Authors: R.H.G. Martins, T.M. Gon�§alves, D.S. Neves, T.A. Fracalossi, E.L.M. Tavares and D. Moretti-Ferreira
We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy (one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four pat.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.19.5
- DOI:
- 10.4238/2011.December.19.5
Alteration of coenzyme specificity of malate dehydrogenase from Streptomyces coelicolor A3(2) by site-directed mutagenesis
Authors: Y.D. Ge, P. Song, Z.Y. Cao, P. Wang and G.P. Zhu
We describe here for the first time the alteration of coenzyme specificity of malate dehydrogenase (MDH) from Streptomyces coelicolor A3(2) (ScMDH). In the present study, we replaced four amino acid residues in the Rossmann fold (βB-αC) region of NADH-dependent ScMDH by site-directed mutagenesis with those of NADPH-dependent MDH (Glu42.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.29.3
- DOI:
- 10.4238/2014.July.29.3