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Effect of nimodipine on rat spinal cord injury
Authors: Y.-F. Jia, H.-L. Gao, L.-J. Ma and J. Li
We evaluated the potentially protective effect of nimodipine on rat spinal cord injury. Sprague-Dawley rats received spinal cord injury, and were separated into nimodipine (N = 12) and saline groups (N = 12). Within 1 h of the injury, rats were treated intraperitoneally with nimodipine (1.0 mg/kg) or an equal amount of saline. Treatment was performed 3 ti.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.5
- DOI:
- 10.4238/2015.February.13.5
Developmental changes in the expression of the GLUT2 and GLUT4 genes in the longissimus dorsi muscle of Yorkshire and Tibetan pigs
Authors: Y. Liang, X.M. Yang, Y.R. Gu, X. Tao, Z.Z. Zhong, J.J. Gong, X.H. Chen and X.B. Lv
Glucose transporter proteins 2 and 4 (GLUT2 and GLUT4) play important roles in glucose transport and energy metabolism. Changes in the levels of GLUT2 and GLUT4 mRNA were measured in longissimus dorsi muscle from the lean Yorkshire and fat Tibetan pig breeds at six different time points (1, 2, 3, 4, 5, and 6 months) with quantitative real-time polymerase .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.7
- DOI:
- 10.4238/2015.February.13.7
Clinical application of three-dimensional reconstruction and rapid prototyping technology of multislice spiral computed tomography angiography for the repair of ventricular septal defect of tetralogy of Fallot
Authors: X.J. Ma, L. Tao, X. Chen, W. Li, Z.Y. Peng, Y. Chen, J. Jin,X.L. Zhang, Q.F. Xiong, Z.L. Zhon and X.F. Chen
Three-dimensional (3D) reconstruction and rapid proÃ?Âtotyping technology (RPT) of multislice spiral computed tomography angiography (CTA) was applied to prepare physical models of the heart and ventricular septal defects of tetralogy of Fallot (ToF) patients in order to explore their applications in the diagnosis and treatment of this complex heart disease.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.9
- DOI:
- 10.4238/2015.February.13.9
Agrobacterium-mediated transformation of tomato (Solanum lycopersicum L.) using the expansin 10 (CsEXP10) gene
Authors: Y.D. Sun, W.R. Luo, S.Y. Sun and L. Ni
The cucumber expansin 10 (CsEXP10) gene was previously cloned from young cucumber fruits but its role has not been defined. To determine the role of this gene in plant growth and development, a CsEXP10 gene transformation system was established. The open reading frame of the gene was inserted behind the CaMV35S promoter of vector pCAMBIA1301, and the cons.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Clinical analysis of patients with myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis
Authors: Z.W. Shuai, Y.F. Lv, M.M. Zhang and Z.Y. Hu
This prospective study analyzed the clinical characteristics of myeloperoxidase antineutrophil cytoplasmic antibody (MPOANCA)-associated vasculitis and explored the relationship between MPO-ANCA and clinical manifestations of the associated vasculitis in 132 p-ANCA and MPO-ANCA-positive patients (average age, 62.3 ± 14.8 years) who were initially d.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.22
- DOI:
- 10.4238/2015.May.18.22
Fyn arrests swainsonine-induced apoptosis in 293T cells via Akt and its phosphorylation
Authors: L. An, W.W. Li and G.C. Cheng
Swainsonine (SW), an extract from Astragalus membranaceus, represents a new class of compounds that inhibit growth and induce apoptosis in a cancer model. In this study, we demonstrated the effect of Fyn on SW-induced apoptosis in 293T cells. Western blotting was used to measure the expression of the apoptosis-related factors caspase-3, Bcl-2, Bax, and th.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.23
- DOI:
- 10.4238/2015.May.18.23
Mechanism of SEMA3B gene silencing and clinical significance in glioma
Authors: C.H. Pang, W. Du, J. Long and L.J. Song
The aim of the current study was to explore mechanisms of SEMA3B gene expression and its clinical significance in glioma, and provide a theoretical foundation for investigating individualized treatment in glioma. Paraffin-embedded tissues from 43 patients with a confirmed clinical diagnosis of glioma following neurosurgery at the First Affiliated Hospital.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017664
- DOI:
- 10.4238/gmr.15017664
Molecular phylogenetics of the white-lipped peccary (Tayassu pecari) did not confirm morphological subspecies in northwestern South America
Authors: M. Ruiz-GarcÃ?Âa, M. Pinedo-Castro, K. Luengas-Villamil, C. VergaraJ.A. Rodriguez and J.M. Shostell
We sequenced the mitochondrial DNA (mtDNA) control region of 59 peccaries (44 white-lipped peccaries, Tayassu pecari, and 15 collared peccaries, Pecari tajacu). We also genotyped 3 DNA microsatellites from 78 white-lipped peccaries representing the 4 putative morphological subspecies (i.e., spiradens, aequatoris, pecari, and albirostris) present in northw.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.6
- DOI:
- 10.4238/2015.May.22.6
Carcass and meat quality traits in Nellore and F1 Nellore-Araguaia crosses
Authors: N.V. Costa, C. Aboujaoude, G.S. Vieira, V.V. Paiva, R.A. Moraes Neto,V.S. Gondim, L.R. Alves, M.C.L. Torres and R.C. Antunes
We evaluated and compared carcass traits and meat quality in Nellore cattle and F1 crosses between Nellore and Araguaia, where 17 individuals were from the Nellore group and 19 were ½ Nellore and ½ Araguaia crosses. All animals belonged to the same birth season and were raised in pasture systems under the same nutritional, environmental, and.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.7
- DOI:
- 10.4238/2015.May.22.7
Tissue culture characteristics of maize (Zea mays L.) haploid coleoptile sections
Authors: L. Jiang, G.X. Jing, X.Y. Li, X.Q. Wang, Z. Xing, P.K. Deng and R.G. Zhao
Doubled haploid (DH) technology, which is used for rapidly purifying genetic resources, is a key technology in modern maize breeding. The present study evaluated the tissue culture characteristics of maize haploid coleoptile sections, in order to provide a new way of haploid doubling. With 20 combinations of haploid coleoptile sections, obtained by hybrid.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015