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Plant Genetics   Research Article

Antifungal and antibacterial activities of Petroselinum crispum essential oil

Authors: G.A. Linde, Z.C. Gazim, B.K. Cardoso, L.F. Jorge, V. Te�¡evi��, J. Glamo��lija, M. Sokovi�� and N.B. Colauto

Parsley [Petroselinum crispum (Mill.) Fuss] is regarded as an aromatic, culinary, and medicinal plant and is used in the cosmetic, food, and pharmaceutical industries. However, few studies with conflicting results have been conducted on the antimicrobial activity of parsley essential oil. In addition, there have been no reports of essential oil obtained f.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038538
DOI:
10.4238/gmr.15038538
Medical Genetics   Research Article

Analysis of interaction between Bmhrp28 and BmPSI in sex-specific splicing of Bombyx mori Bmdsx gene

Authors: X.F. Zha, M. Zhao*, C.Y. Zhou, H.Z. Guo, P. Zhao, Z.H. Xiang and Q.Y. Xia

Bombyx mori BmHRP28 and BmPSI, which belong to the family of RNA-binding proteins, have been identified binding to the female-specific exon 4 of the sex-determining gene Bmdsx pre-mRNA. However, the relationships between BmHRP28 and BmPSI still remain unclear. In this study, we carried out yeast two-hybrid (Y.. Read More»

Genet. Mol. Res. 13(3):
2014.July.24.25
DOI:
10.4238/2014.July.24.25
Medical Genetics   Research Article

Recent progress in identification and characterization of loci associated with sex-linked congenital cataract

Authors: D.D. Zhang, J.Z. Du, J. Topolewski and X.M. Wang

Congenital cataract is a common cause of blindness in children; however, its pathogenesis remains unclear. Genetic factors have been shown to play an important role in the pathogenesis of congenital cataract. The current genetic models of congenital cataract include autosomal dominant, autosomal recessive, and sex-linked inheritance. Sex-linked congenital.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038600
DOI:
10.4238/gmr.15038600
Plant Genetics   Research Article

Mendelian inheritance, linkage, and genotypic disequilibrium in microsatellite loci of Hymenaea stigonocarpa Mart. ex Hayne (Fabaceae-Caesalpinioideae)

Authors: M.A. Moraes, T.Y.K. Kubota, E.C.B. Silva, A.M. Silva, J. Cambuim, M.L.T. Moraes, E. Furlani Junior and A.M. Sebbenn

Hymenaea stigonocarpa is a deciduous and monoecious Neotropical tree species pollinated by bats. Due to overexploitation and habitat destruction, the population size has drastically diminished in nature. No previous study has investigated Mendelian inheritance, linkage, and genotypic disequilibrium in the available microsatellite markers in this species. .. Read More»

Genet. Mol. Res. 15(3):
gmr.15038629
DOI:
10.4238/gmr.15038629
Medical Genetics   Research Article

Isolation and characterization of a novel acidic matrix protein hic22 from the nacreous layer of the freshwater mussel, Hyriopsis cumingii

Authors: X.J. Liu, C. Jin, L.M. Wu, S.J. Dong, S.M. Zeng and J.L. Li

Matrix proteins that either weakly acidic or unusually highly acidic have important roles in shell biomineralization. In this study, we have identified and characterized hic22, a weakly acidic matrix protein, from the nacreous layer of Hyriopsis cumingii. Total protein was extracted from the nacre using 5 M EDTA and hic22 was purified using a DEAE-sepharo.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038656
DOI:
10.4238/gmr.15038656
Human Genetics   Research Article

Changes and clinical significance of serum vaspin levels in patients with type 2 diabetes

Authors: L. Yang, S.J. Chen, G.Y. Yuan, D. Wang and J.J. Chen

We investigated serum visceral adipose tissue-derived serpin (vaspin) levels in patients with normal glucose regulation and recently diagnosed type 2 diabetes (T2DM) and explored the association between vaspin and body mass index, age, gender, glucose, lipid metabolism, and insulin sensitivity. Fasting serum vaspin levels in 66 patients with T2DM and 48 n.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.September.25.2
DOI:
http://dx.doi.org/10.4238/2015.September.25.2
Human Genetics   Research Article

Effect of RAGE polymorphisms on susceptibility to and severity of osteoarthritis in a Han Chinese population: a case-control study

Authors: H.Y. Yang, S.Y. Chuang, W.H. Fang, G.S. Huang, C.C. Wang, Y.Y. Huang, M.Y. Chu, C. Lin, W. Su, C.Y. Chen, Y.T. Yang and S.L. Su

Recent studies have revealed that the inflammatory process plays a role in the pathogenesis of osteoarthritis (OA). The S100 family and receptor for advanced glycation end products (RAGE)participate in regulating inflammation, even in the production of matrix metalloproteinases (MMPs). MMP-1 degrades cartilage, which may result in OA development. Moreover.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.25.3
DOI:
http://dx.doi.org/10.4238/2015.September.25.3
Animal Genetics   Research Article

Sequence variation in ROP8 gene among Toxoplasma gondii isolates from different hosts and geographical localities

Authors: Z.Y. Li, J. Chen, J. Lu, C.R. Wang and X.Q. Zhu

The protozoan parasite Toxoplasma gondii has a worldwide distribution; it can cause serious diseases in humans and almost all other warm-blooded animals. Different genotypes of T. gondii result in different lesions in the same host. T. gondii rhoptry protein 8 (TgROP8) is a major factor of T. gondii acute virulence. We examined sequence variation in the T.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.25.8
DOI:
http://dx.doi.org/10.4238/2015.September.25.8
Plant Genetics   Research Article

Natural variation of rice blast resistance gene Pi-d2

Authors: J.B. Li, Y.D. Sun, H. Liu, Y.Y. Wang, Y.L. Jia and M.H. Xu

Studying natural variation in rice resistance genes of cultivated and wild rice relatives can predict resistance stability to rice blast fungus. In the present study, the protein coding regions of the rice R gene Pi-d2 in 35 rice accessions, including Oryza sativa L. subsp. indica Kato (Aus), indica (IND), temperate japonica (TEJ), tropical japonica (TRJ), a.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.2
DOI:
10.4238/2015.February.13.2
Plant Genetics   Short communication

Isolation of microsatellite loci for Rhodiola alsia (Crassulaceae), an important ethno-medicinal herb endemic to the Qinghai-Tibetan plateau

Authors: F.Q. Zhang, S.Y. Lei, Q.B. Gao, G. Khan, R. Xing, H.L. Yang and S.L. Chen

Rhodiola alsia, which has been used widely in traditional Chinese medicine for a considerable time, grows on moist habitats at high altitude near the snow line. Microsatellite loci were developed for R. alsia to investigate its population genetics. In total, 17 polymorphic microsatellites were developed based on ESTs from the Illumina HiSeqTM 2000 platfor.. Read More»

Genet. Mol. Res. 14(2):
2015.May.18.18
DOI:
10.4238/2015.May.18.18