Polymorphism
Associations between the SRD5A2 gene V89L and TA repeat polymorphisms and breast cancer risk: a meta-analysis
Authors: D. Zhang, Q. Li, H.-C. Qu, T. Yu and Y.-R. Liu
The 5α-reductase type 2 (SRD5A2) gene plays a significant role in the development of breast cancer. The V89L and TA repeat polymorphisms of the SRD5A2 gene have been considered as risk factors for breast cancer. However, the results have been inconsistent. To resolve this conflict, we performed a meta-analysis of studies with V89L (1144 patients and.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.9
- DOI:
- 10.4238/2015.August.7.9
Association of MyoD1a and MyoD1b gene polymorphisms and meat quality traits in rainbow trout
Authors: W.X. Chen, Y. Ma and K.H. Liu
In this study, we identified myogenic regulatory factors (MRFs) and analyzed the correlation between MRFs and meat quality in rainbow trout. The MyoD1a and MyoD1b genes were cloned from rainbow trout using a homology cloning method. Introns 1 and 2 in the MyoD1a and MyoD1b genes were cloned and submitted to GenBank (accession Nos. FJ623462 and FJ793566). .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.12
- DOI:
- 10.4238/2015.August.7.12
Association between MTHFR 677C/T polymorphism and psoriasis risk:a meta-analysis
Authors: J.H. Qi,J.H. Qi,N. Shi,Y.J. Chen and G. Nie
Previous studies investigating the association between methylenetetrahydrofolate reductase (MTHFR) 677C/T polymorphisms and psoriasis risk have reported inconsistent results. The present meta-analysis aimed to comprehensively evaluate the association between MTHFR 677C/T polymorphism and psoriasis risk. The studies regarding the association between MTHFR .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.16
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.16
Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis
Authors: Y.H. Lee and G.G. Song
The aim of this study was to determine whether vitamin D receptor (VDR) genetic polymorphisms are associated with the susceptibility to pulmonary tuberculosis (PTB). MEDLINE and Embase databases and manual literature searches were used. A meta-analysis was conducted on the associations between the VDR FokI, TaqI, BsmI, and ApaI polymorphisms and PTB susce.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.21
- DOI:
- 10.4238/2015.August.7.21
Relationship of the APOA5/A4/C3/A1 gene cluster and APOB gene polymorphisms with dyslipidemia
Authors: H.J. Ou, G. Huang, W. Liu, X.L. Ma, Y. Wei, T. Zhou and Z.M. Pan
We determined the alleles of ten single nucleotide polymorphisms (SNPs) in the APOA5/A4/C3/A1 gene cluster and in APOB in Han Chinese from Xinjiang Shihezi, China using MALDI-TOF mass spectrometry, and explored the correlation between these SNPs and dyslipidemia through a case-control study design with 250 patients and 250 normal controls. All S.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.10.8
- DOI:
- 10.4238/2015.August.10.8
IL-17A and IL-17F polymorphisms and gastric cancer risk: a meta-analysis
Authors: Z. Li, Y. Liu, D. Cao, M. Jiang and F. Luo
We conducted a meta-analysis of eligible studies to estimate the association between gastric cancer risk and rs2275913G>A IL-17A and rs763780T>C IL-17F polymorphisms. We searched the relevant studies in both Chinese and English through PubMed, the Web of Science, the Cochrane Library, and EMBASE up to January 1, 2014, including 3939 cases and 5407 c.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.10
- DOI:
- 10.4238/2015.June.26.10
Independent and joint effects of the IL-6 and IL-10 gene polymorphisms in pulmonary tuberculosis among the Chinese Han population
Authors: F.M. Feng, X.X. Liu, Y.H. Sun, P. Zhang, S.F. Sun, B. Zhang, X.T. Wang and L.J. Lu
We investigated the association between interleukin (IL)-6 and IL-10 gene polymorphisms and the susceptibility to pulmonary tuberculosis (PTB). DNA samples were obtained from 191 Han Chinese patients with PTB and 191 healthy control subjects. IL-6 (-572, -174, -597) and IL-10 (-1082, -819) polymorphisms were analyzed using pol.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.14
- DOI:
- 10.4238/2014.September.26.14
Association of vitamin D receptor BsmI gene polymorphism with risk of low bone mineral density in post-menopausal women: a meta-analysis
Authors: C. Ma, Q.L. Zhou, Y.J. Deng, X. Liang, D.P. Wu and Y.Z. Dong
The vitamin D receptor BsmI gene polymorphism is reportedly associated with low bone mineral density (BMD) in postmenopausal women, but results from previous studies are conflicting. In the present study, we investigated the association between this polymorphism and the risk of low BMD through a meta-analysis of published stud.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.17
- DOI:
- 10.4238/2014.September.26.17
Association between adiponectin receptor 2 gene polymorphisms and cerebral infarction
Authors: B. Yuan and J.F. Teng
We examined the association between the adiponectin receptor 2 gene and the risk of ischemic stroke. Polymerase chain reaction-restriction fragment length polymorphism was used to detect rs12342 genotypes of the adiponectin receptor 2 gene in 300 ischemic stroke patients and 320 age- and gender-matched healthy controls. In the.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.19
- DOI:
- 10.4238/2014.September.26.19
Assessment of genetic diversity of Tunisian orange, Citrus sinensis (L.) Osbeck using microsatellite (SSR) markers
Authors: A. Mahjbi, A. Oueslati, G. Baraket, A. Salhi-Hannachi and S. Zehdi Azouzi
Citrus are one of the most cultivated crops in the world. Economically, they are very important fruit trees in Tunisia. Little is known about the genetic diversity of the Tunisian Citrus germplasm. Exploring this diversity is a prerequisite for the identification and characterization of the local germplasm to circumvent and co.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026564
- DOI:
- 10.4238/gmr.15026564