Polymorphism
Association between ACP1 genetic polymorphism and favism
Authors: V. Polzonetti, V. Passini and N. Lucarini
An association between favism (a hemolytic reaction to consumption of fava beans), glucose-6-phosphate dehydrogenase deficiency (G6PD-) and acid phosphatase locus 1 (ACP1) phenotypes has been reported; the frequency of carriers of the pa and pc ACP1 alleles was found to be significantly higher in G6PD- individuals showing favi.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1062
- DOI:
- 10.4238/vol10-2gmr1062
Association of TSC gene variants and hypertension in Mongolian and Han populations
Authors: P.Y. Chang, L.G. Zhao and X.L. Su
We investigated a possible association between genetic variations in the thiazide-sensitive Na-Cl cotransporter (TSC) gene and essential hypertension (EH) in the Mongolian and Han ethnic groups in Inner Mongolia. Our study included 385 unrelated Mongolian herdsmen and 523 Han farmers. Nine tagSNPs of TSC were identified from t.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1227
- DOI:
- 10.4238/vol10-2gmr1227
Polymorphisms in the delta-like 2 homolog gene and their association with growth and meat-quality traits in Qinchuan cattle
Authors: N. Yang, L.S. Zan, Y.K. Li, J.B. Gao, X.H. Ma, C.Z. Fu, H. Wang and C. Adoligbe
The delta-like 2 homolog (DLK2) modulates adipogenesis, hematopoiesis, osteogenesis, and other cell-differentiation processes. In the present study, we detected potential polymorphisms in the DLK2 gene in 604 individuals of Qinchuan cattle by using PCR-RFLP and DNA-sequencing methods. Herein, we identified five novel single-nu.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.20
- DOI:
- 10.4238/2014.March.24.20
TP53 gene polymorphisms at codons 11, 72, and 248 and association with endometriosis in a Brazilian population
Authors: C.M. Camargo-Kosugi, P. D�Amora, J.P.F.O. Kleine, C.V. Carvalho, H. Sato, E. Schor and I.D.C.G. Silva
We evaluated the association between TP53 gene polymorphisms and endometriosis in Brazilian women. Genomic DNA was extracted from swabs of buccal cells collected from hospital patients. TP53 gene polymorphisms were investigated at three codons: TP53*11 Glu/Gln or Lys (GAG->CAG or AAG), TP53*.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.26.1
- DOI:
- 10.4238/2014.August.26.1
Association of variable number of tandem repeats polymorphism in the IL-4 gene with end-stage renal disease in Malaysian patients
Authors: R. Vasudevan, M.N. Norhasniza and I. Patimah
Variable number of tandem repeats (VNTR) polymorphism in the interleukin 4 (IL-4) gene has been associated with end-stage renal disease (ESRD) subjects in many different populations, although with conflicting results. We determined the 70 bp of VNTR polymorphism at intron 3 of the IL-4 gene in Malaysian ESRD subjects. Buccal c.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1066
- DOI:
- 10.4238/vol10-2gmr1066
Lack of association of variants of the renal salt reabsorption-related genes SLC12A3 and ClC-Kb and hypertension in Mongolian and Han populations in Inner Mongolia
Authors: P.Y. Chang, X.G. Zhang and X.L. Su
Abnormalities in renal sodium chloride and water reabsorption play important roles in the development of hypertension. Mutations in the genes involved in renal sodium chloride reabsorption can affect blood pressure. Recently, the R904Q variant of the sodium/chloride transporters, member 3 (SLC12A3) gene and the T481S variant o.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1165
- DOI:
- 10.4238/vol10-2gmr1165
Genetic analysis of 30 InDel markers for forensic use in five different Chinese populations
Authors: C.T. Li, S.H. Zhang and S.M. Zhao
Allele frequencies of 30 insertion/deletion polymorphism (InDel) markers previously selected and validated for forensic purposes were assessed in 419 unrelated individuals originating from five different populations of P.R. China, including Chinese Han, Chinese Hui, Uighur, Mongolians, and Tibetans. Hardy-Weinberg equilibrium .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1082
- DOI:
- 10.4238/vol10-2gmr1082
Variations in BARE-1 insertion patterns in barley callus cultures
Authors: C. Evrensel, S. Yilmaz, A. Temel and N. Gozukirmizi
The stability of aging barley calli was investigated with the barley retroelement 1 (BARE-1) retrotransposon specific inter-retrotransposon amplified polymorphism (IRAP) technique. Mature embryos of barley (Hordeum vulgare cv. Zafer-160) were cultured on callus induction MS medium supplemented with 3 mg/L 2,4-D and maintained .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr965
- DOI:
- 10.4238/vol10-2gmr965
A new high-frequency allele of the BM2113 locus in the Yunnan mithun population
Authors: K.-X. Qu, Z.-X. He, R.-J. Hao, J.-C. Zhang, B.-Z. Huang,L.-S. Zan, and Y.-P. Zhang
The BM2113 locus was amplified in Yunnan mithun (Bos frontalis) from the southwest mountains of China. It showed a high degree of polymorphism with a total of 12 alleles. The 121-bp polymorphic allele of the BM2113 locus that accounted for 37.1% of homozygotes was the predominant allele with a frequency of 58.57%, identified a.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.23
- DOI:
- 10.4238/2014.March.24.23
H558R polymorphism in SCN5A is associated with Keshan disease and QRS prolongation in Keshan disease patients
Authors: S. Jiang, F.L. Li, Q. Dong, H.W. Liu, C.F. Fang, C. Shu, H. Cheng, J. Cui, H.X. Ma, D.Q. Chen, H. Li
Keshan disease (KSD), a potentially fatal cardiomyopathy, has very high incidence in some selenium-poor regions of China. KSD may be accompanied with a variety of arrhythmia, which is associated with mutations in the gene coding for cardiac voltage-gated sodium channel (SCN5A). The molecular mechanism of KSD is still .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.28.1
- DOI:
- 10.4238/2014.August.28.1