Polymorphism
Association between �²1 adrenergic receptor gene Arg389Gly polymorphism and risk of heart failure: a meta-analysis
Authors: S.T. Ma, W. Zhao,B. Liu, R.Y. Jia, C.J. Zhao and L.Q. Cui
Numerous studies have evaluated the association between Arg389Gly polymorphism in the β1 adrenergic receptor gene and heart failure risk. However, the specific association is still controversial. We performed a meta-analysis of all case-control studies that evaluated the association between Arg389Gly polymorphism and heart failure in humans. Studies .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.9
- DOI:
- 10.4238/2015.June.1.9
Polymorphisms of three new microsatellite sites of the dystrophin gene
Authors: R.F. Sun, Y.S. Zhu, J.L. Feng, Z. Tian, W.J. Kuang, Y. Liu, H.B. Zhang and S.B. Li
To look for novel microsatellites in the dystrophin gene for the diagnosis of Duchenne muscular dystrophy, candidate microsatellite sites in the dystrophin gene were analyzed with the SSRHunter software and were also genotyped. Among the 15 candidate microsatellite sites, three novel microsatellite sites in the 60th, 30th, and.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr962
- DOI:
- 10.4238/vol10-2gmr962
Lack of association between Gly82Ser, 1704G/T and 2184A/G of RAGE gene polymorphisms and retinopathy susceptibility in Malaysian diabetic patients
Authors: Z.X. Ng, U.R. Kuppusamy, R. Poh, I. Tajunisah, A.C.A. Koay, K.C.S. Fong and K.H. Chua
Diabetic retinopathy is the most common diabetic eye disease, occurring in about 60% of type 2 diabetic patients. Other than known clinical risk factors, the influence of genes has been suggested as part of the development of diabetic retinopathy. We investigated the association of Gly82Ser, 1704G/T and 2184A/G polymorphisms i.. Read More»
- Genet. Mol. Res. 11(1):
- 2012.March.1.2
- DOI:
- 10.4238/2012.March.1.2
Detection of differentially expressed genes in the longissimus dorsi of Northeastern Indigenous and Large White pigs
Authors: Y. Gao, Y.H. Zhang, H. Jiang, S.Q. Xiao, S. Wang, Q. Ma, G.J. Sun, F.J. Li, Q. Deng, L.S. Dai, Z.H. Zhao, X.S. Cui, S.M. Zhang, D.F. Liu and J.B. Zhang
Recent attention in pig breeding programs has focused on the improvement of pork quality in response to increasing consumer demands. Compared to the fatty-type Northeastern Indigenous (Chinese) breed of pigs, the lean-type Large White has lower intramuscular fat and inferior eating quality from the perspective of the Chinese c.. Read More»
- Genet. Mol. Res. 10(2):
Cox-2 gene polymorphism and IL-6 levels in coronary artery disease
Authors: K.K. Ol, B. Agachan, U. Gormus2, B. Toptas and T. Isbir
Coronary artery disease is one of the leading causes of mortality and diabetes mellitus is one of its main risk factors due to microvascular and macrovascular complications, such as atherosclerosis. Atherosclerosis is now known to be an inflammatory process mediated by prostaglandins and several interleukins. As both are impor.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr967
- DOI:
- 10.4238/vol10-2gmr967
Association between the polymorphisms in the ATP-binding cassette genes ABCB1 and ABCC2 and the risk of drug-resistant epilepsy in a Chinese Han population
Authors: T. Xue and Z.N. Lu
Epilepsy is a common disease of the nervous system; approximately 20-30% of all patients with epilepsy are reported resistant to antiepileptic drugs. ABCB1 and ABCC2 are members of ATP-binding cassette transporter (ABC) family that is involved in the excretion of antiepileptic drugs. In this case-control study, we have investi.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048752
- DOI:
- 10.4238/gmr15048752
Ala-9Val polymorphism of Mn-SOD gene in sickle cell anemia
Authors: S. Sogut, Z. Yonden, H. Kaya, S. Oktar, M. Tutanc, H.R. Yilmaz, A. Yigit, N. Ozcelik and E. Gali
Oxidative stress may be contributory to the pathophysiology of the abnormalities that underlie the clinical course of sickle cell anemia. We looked for a possible genetic association between the functional polymorphism Ala-9Val in the human Mn-SOD gene and sickle cell anemia. One hundred and twenty-seven patients with sickle c.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1106
- DOI:
- 10.4238/vol10-2gmr1106
Karyotypic diversity in a population of Bryconamericus aff. iheringii (Characidae)
Authors: L.L.L. da Silva, L. Giuliano-Caetano and A.L. Dias
Bryconamericus comprises 56 species distributed into three groups, on the basis of the position and shape of the maxillary teeth: B. exodon, B. microcephalus and B. iheringii groups. Few cytogenetic data are available for this genus, but the diploid number of 52 chromosomes is quite common, although the karyotypic variability .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.11
- DOI:
- 10.4238/2014.March.24.11
Association of a disintegrin and metalloproteinase 33 (ADAM33) gene polymorphisms with chronic obstructive pulmonary disease in the Chinese population: A meta-analysis
Authors: D.D. Li, S.J. Guo, L.Q. Jia and F.Q. Wen
Numerous studies have evaluated the association between polymorphisms of a disintegrin and metalloproteinase 33 (ADAM33) gene and chronic obstructive pulmonary disease (COPD) risk; however, the results remain conflicting. The aim of this study was to investigate whether ADAM33S2 and -T1 polymorphisms are associated with suscep.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.2
- DOI:
- 10.4238/2014.August.25.2
Genome-wide association study on growth traits in Colombian creole breeds and crossbreeds with Zebu cattle
Authors: R. MartÃ?Ânez, Y. GÃ?³mez and J.F.M. Rocha
Whole genome selection represents an important tool for improving parameters related to the production of livestock. In order to build genomic selection indexes within a particular breed, it is important to identify polymorphisms that have the most significant association with a desired trait. A genome-wide marker association .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.5
- DOI:
- 10.4238/2014.August.25.5