Polymorphism

The mutation G298A��?Ala100Thr on the coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians

Authors: Angela Cristina Estalote, Rodrigo Proto-Siqueira, Wilson Ara�?ºjo Da Silva Jr., Marco Antonio Zago and Marcos Palatnik

Ala100Thr has been suggested to be a Caucasian genetic marker on the FY*B allele. As the Brazilian population has arisen from miscegenation among Portuguese, Africans, and Indians, this mutation could possibly be found in Euro- and Afro-Brazilians, or in Brazilian Indians. Fifty-three related individuals and a random sample of.. Read More»

Genet. Mol. Res. 4(2):

Effects of polymorphisms of LHR and FSHR genes on sexual precocity in a Bos taurus x Bos indicus beef composite population

Authors: E.P. Marson, J.B.S. Ferraz, F.V. Meirelles, J.C.C. Balieiroand J.P. Eler

The purpose of the present research was to investigate the effects of polymorphisms of luteinizing hormone receptor (LHR) and follicle-stimulating hormone receptor (FSHR) genes, evaluated by polymerase chain reaction-restriction fragment length polymorphism in European-Zebu composite beef heifers from six different breed compo.. Read More»

Genet. Mol. Res. 7(1):

Prognostic value of TP53 Pro47Ser and Arg72Pro single nucleotide polymorphisms and the susceptibility to gliomas in individuals from Southeast Brazil

Authors: G.R. Pinto, F.K.N. Yoshioka, R.L.L. Silva, C.A. Clara, M.J. Santos, J.R.W. Almeida, R.R. Burbano, J.A. Rey and C. Casartelli

The TP53 tumor suppressor gene codifies a protein responsible for preventing cells with genetic damage from growing and dividing by blocking cell growth or apoptosis pathways. A common single nucleotide polymorphism (SNP) in TP53 codon 72 (Arg72Pro) induces a 15-fold decrease of apoptosis-inducing ability and has been associat.. Read More»

Genet. Mol. Res. 7(1):

vol7-1gmr415

DOI:

10.4238/vol7-1gmr415

Characterization of nine novel microsatellite loci for the Venus clam (Cyclina sinensis)

Authors: J.X. Wang, T.J. Xu, L. Wei, F.X. Meng and R.X. Wang

The Venus clam, Cyclina sinensis, is one of the most important bivalves in China marine aquaculture. Using (CA)15-enriched genomic libraries of this species, nine novel polymorphic microsatellite loci were isolated and characterized. The mean number of observed alleles per locus was 16 (range 8-24). The observed and expected h.. Read More»

Genet. Mol. Res. 11(1):

2012.February.16.3

DOI:

10.4238/2012.February.16.3

Development of novel polymorphic microsatellite markers for the silver fox (Vulpes vulpes)

Authors: S.Q. Yan, C.Y. Bai, S.M. Qi, Y.M. Li, W.J. Li and J.H. Sun

The silver fox (Vulpes vulpes), a coat color variant of the red fox, is one of the most important fur-bearing animals. To date, development of microsatellite loci for the silver fox has been limited and mainly based on cross-amplification by using canine SSR primers. In this study, 28 polymorphic microsatellite markers were isolated and identified for sil.. Read More»

Genet. Mol. Res. 14(2):

2015.June.1.6

DOI:

10.4238/2015.June.1.6

RETRACTION of â�?�?Correlation analysis between an IL-6 genetic polymorphism and non-small cell lung cancer prognosisâ�?, by Zhao K, Xu J, Tian H published in Genetics and Molecular Research 15 (1): 15017021 (2016) DOI: 10.4238/gmr.15017021

Authors: Zhao K, Xu J and Tian H

Genet. Mol. Res. 15(4):

gmr150470211

DOI:

10.4238/gmr150470211

Interleukin-8 -251A/T polymorphism and periodontitis susceptibility: a meta-analysis

Authors: Z.J. Yang, X.P. Tang, Q.G. Lai, J.B. Ci and K.F. Yuan

The -251A/T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene has been implicated in susceptibility to periodontitis; however, this correlation has not been elucidated. In this meta-analysis, we investigated the association between the IL-8 -251A/T polymorphism and the risk of periodontitis. All eligible.. Read More»

Genet. Mol. Res. 15(4):

gmr15047379

DOI:

10.4238/gmr15047379

Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

Authors: F.J. Li, F.W. Jiang, H.K. Bai, H.T. Fu, S.B. Jin, S.M. Sun, H. Qiao and W.Y. Zhang

Increasing evidence suggests that the insulin-like androgenic gland hormone (IAG) gene plays an important role in male sexual differentiation, metabolism, and growth in crustaceans. In the present study, we isolated the full-length genome sequence of IAG by genome walking based on the cDNA sequence in Macrobrachium nipponense. Four novel single nucleotide.. Read More»

Genet. Mol. Res. 14(2):

2015.June.1.8

DOI:

10.4238/2015.June.1.8

Variation in DNA repair gene XRCC3 affects susceptibility to astrocytomas and glioblastomas

Authors: A.C. Cust�?³dio, L.O. Almeida, G.R. Pinto, M.J. Santos, J.R.W. Almeida, C.A. Clara, J.A. Rey and C. Casartelli

The gene XRCC3 (X-ray cross complementing group 3) has the task of repairing damage that occurs when there is recombination between homologous chromosomes. Repair of recombination between homologous chromosomes plays an important role in maintaining genome integrity, although it is known that double-strand breaks are the main .. Read More»

Genet. Mol. Res. 11(1):

2012.February.10.4

DOI:

10.4238/2012.February.10.4

Optimization of a multiplex minisequencing protocol for population studies and medical genetics

Authors: Cl�?¡udia M.B. Carvalho and S�?©rgio D.J. Pena

Several technologically sophisticated high-throughput techniques have been recently developed for the study of human single nucleotide polymorphisms and the diagnosis of point mutations in human diseases. However, there is also a need for simple and inexpensive techniques suitable for clinical services and small research labor.. Read More»

Genet. Mol. Res. 4(2):