Polymorphism
Isolation and characterization of polymorphic microsatellite loci of the Chinese muntjac (Muntiacus reevesi)
Authors: H. Wang, X. Luo, W.B. Shi and B.W. Zhang
Eight polymorphic microsatellite markers for Muntiacus reevesi were identified and characterized in this study. The number of alleles per locus ranged from 3 to 10 across 24-48 samples. The loci showed expected and observed heterozygosities of 0.577-0.876 and 0.387-0.933, respectively, with an average polymorphic information c.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.18
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.18
Common polymorphisms in the HIF-1�± gene confer susceptibility to digestive cancer: a meta-analysis
Authors: J.J. Xu, L.Y. Zou, L. Yang, X.L. He and M. Sun
Recent evidence suggests that common functional polymorphisms in the hypoxia inducible factor-1α (HIF-1α) gene may play an important role in the development and progression of digestive cancer, but individually published results are inconclusive. Our meta-analysis is aimed to derive a more precise estimation of the.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.5
- DOI:
- 10.4238/2014.August.15.5
Isolation, characterization, and cross-transferability of microsatellite markers from the whitebacked planthopper (Sogatella furcifera)
Authors: L. Zhang, G. Li, G.C. He, L.L. Zhu, R. Qin and S.L. Jing
The whitebacked planthopper Sogatella furcifera (Horváth) (Hemiptera: Delphacidae) is one of the most harmful pests of rice. In this study, 18 polymorphic microsatellite markers were developed from S. furcifera genomic libraries using the fast isolation by amplified fragment length polymorphism of sequences containing r.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.15.7
- DOI:
- 10.4238/2014.August.15.7
ABO genotyping in leukemia patients reveals new ABO variant alleles
Authors: M.C.Z. Novaretti, A.E. Domingues, R. Manhani, E.M. Pinto, P.E. Dorlhiac-Llacer and D.A.F. Chamone
The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the .. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr401
- DOI:
- 10.4238/vol7-1gmr401
Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence
Authors: N. Wang1*, J.B. Zhang1*, J. Zhao1, X.T. Cai1, Y.S. Zhu1,2 and S.B. Li1,2
Heroin dependence is a chronic relapsing brain disease. Researchers have reported that the dopamine D2 receptor (DRD2) is involved in the development of opiate dependence. To identify markers that contribute to the genetic susceptibility to heroin addiction, we examined the potential association between heroin dependence and s.. Read More»
- Genet. Mol. Res. 15(4):
- http://dx.doi.org/gmr15048772
- DOI:
- http://dx.doi.org/10.4238/gmr15048772
Lack of an association between a single nucleotide polymorphism in the bovine myogenic determination 1 (MyoD1) gene and meat quality traits in indigenous Chinese cattle breeds
Authors: J.A. Ujan, L.S. Zan, H.B. Wang, S.A. Ujan, C. Adoligbe, H.C. Wang and S.F. Biao
The myogenic determination 1 (MyoD1) gene is a member of the MyoD gene family. It encodes for skeletal muscle-specific transcription factors containing highly conserved basic helix-loop-helix regions that perform important roles in the initiation, maintenance, and regulation of phenotypic traits. We investigated a new single n.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1141
- DOI:
- 10.4238/vol10-3gmr1141
Frequency distribution of interleukin-10 haplotypes (-1082 A>G, -819 C>T, and-592 C>A) in a Mexican population
Authors: M. V�¡zquez-Villamar, C.A. Palafox-S�¡nchez, J. Hern�¡ndez-Bello,J.F. Mu�±oz-Valle, Y. Valle, A. Cruz, A.I. Alatorre-Meza and E. Oregon-Romero
Interleukin 10 (IL-10) is an immunoregulatory cytokine with multiple roles in the immune system. Three single nucleotide polymorphisms at positions -1082 (A>G), -819 (C>T), and -592 (C>A) in the promoter region of the IL10 gene are believed to be associated with different inflammatory, infectious, and autoimmune disea.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048411
- DOI:
- 10.4238/gmr15048411
Association between Ser311Cys polymorphism in the dopamine D2 receptor gene and schizophrenia risk: a meta-analysis in Asian populations
Authors: Z.W. Liu, J.L. Liu, Y. An, L. Zhang and Y.M. Wang
Numerous studies have evaluated the association between Ser311Cys (rs1801028, C>G) polymorphism of the dopamine D2 receptor (DRD2) gene and schizophrenia risk. However, the specific association is still controversial. We examined whether DRD2 Ser311Cys polymorphism confers schizophrenia risk in Asian populations. Sixteen st.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.February.8.1
- DOI:
- http://dx.doi.org/10.4238/2012.February.8.1
Association between the PPAR�³ Pro12Ala polymorphism and risk of gestational diabetes mellitus: a meta-analysis
Authors: H.L. Shuai, X.Z. Lin, D.L. Chen, P. Li and X. Luo
The relationship between the Pro12Ala polymorphism of PPARγ and the risk of gestational diabetes mellitus remains unresolved. Here, we attempted to resolve this inconsistency. Case-control studies pertaining to the effect of the Pro12Ala polymorphism in the PPARγ protein and risk of gestational diabetes mellitus we.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047682
- DOI:
- 10.4238/gmr15047682
Is there any association between childhood cardiac septal defects and ROCK2 gene polymorphism?
Authors: M. Aksoy, H. Uygun, O. Baspinar, S. Demiryurek, S. Oztuzcu,B. Cengiz, A. Irdem and N.C. Araz
Rho/Rho-kinase pathway plays a critical role in the regulation of cellular functions such as proliferation and migration. One of the possible theories of the development of ventricular septal defects is cell migration disorder. The aim of this study was to analyze the genotype distributions and allele frequencies for the ROCK2 gene Thr431Asn polymorphisms.. Read More»
- Genet. Mol. Res. 13(1):