Gene
Screening of key genes of unruptured intracranial aneurysms by using DNA microarray data analysis techniques
Authors: L. Chen, Y. Fan and J. Wan
This study aimed to identify differentially expressed genes (DEGs) of unruptured intracranial aneurysms (IAs) and provide beneficial information for early diagnosis and treatment of IAs. The gene expression profile GSE26969 from the Gene Expression Omnibus database was downloaded, which included six human IA samples: three int.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.31.2
- DOI:
- 10.4238/2014.January.31.2
De novo assembly and characterization of Gleditsia sinensis transcriptome and subsequent gene identification and SSR mining
Authors: S. Han, Z. Wu, X. Wang, K. Huang, Y. Jin, W. Yang and H. Shi
Gleditsia sinensis is a Chinese native deciduous tree with a high economic and medicinal value. However, there is limited knowledge on the molecular processes responsible for the medical properties of this species owing to lack of bioinformatic resources such as available whole-genome sequences. In the present study, RNA sequencing data were used to analy.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017740
- DOI:
- 10.4238/gmr.15017740
FISH, PCR and cytogenetic characterization in a girl with ambiguous genitalia and karyotype mos46,X,iso(Y)(qter�p11.3::p11.3�qter)[80]/ 45,X[17]/46,X,+mar[3]
Authors: S.R.F. Pereira, A.C.N. Pereira, M.T.V.L. Souza and M.R.B.P. Ramos
A cytogenetic study was carried out in a girl with virilized external genitalia , whoshowed a karyotype containing a isochromosome in mosaic form: mos46,X,iso(Y)(qter→p11.3::p11.3→qter)[80]/45,X[17]/46,X,+mar[3]. T The chromosome aberrations were confirmed by fluorescence in situ hybridization analysis, with both whole chromosome paint Y probe a.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr483
- DOI:
- 10.4238/vol7-4gmr483
Genetic evidence for panmixia of Japanese eel (Anguilla japonica) populations in China
Authors: X.L. Gong, S.J. Ren, Z.K. Cui and L.J. Yue
The Japanese eel population has dramatically declined since the 1970s. In order to conserve this species, the background genetic structure affecting these populations should be well documented. Previous genetic studies of this species have produced seemingly conflicting results, ranging from no detectable heterogeneity to smal.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.31.3
- DOI:
- 10.4238/2014.January.31.3
Association of PS1 1/2, ACE I/D, and LRP C/T polymorphisms with Alzheimer�s disease in the Chinese population: a meta-analysis of case-control studies
Authors: L. Yang, H.-H. Zhou, Y.-F. Ye, X.-W. Fan, Y.-J. Wang and Y. Meng
The objective of this study was to assess the associations of presenilin 1 (PS1) 1/2, angiotensin I-converting enzyme (ACE) insertion/deletion (I/D), and low-density lipoprotein receptor-related protein (LRP) C/T polymorphisms with the risk of Alzheimer’s disease (AD) in the Chinese population. PS1 1/2, ACE I/D, and LRP C/T, which are commonly inves.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.5
- DOI:
- 10.4238/2015.February.6.5
Isolation and characterization of microsatellite markers for Axonopus compressus (Sw.) Beauv. (Poaceae) using 454 sequencing technology
Authors: X.-L. Wang, Y. Li, L. Liao, C.-J. Bai and Z.-Y. Wang
Axonopus compressus (Sw.) Beauv. is a perennial herb widely used as a garden lawn grass. In this study, we used Roche 454 pyrosequencing, combined with the magnetic bead enrichment method FIASCO, to isolate simple sequence repeat markers from the A. compressus genome. A total of 1942 microsatellite loci were identified, with 53,193 raw sequencing reads. O.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.2
- DOI:
- 10.4238/2015.May.11.2
DNA sequence polymorphism within the bovine adenosine monophosphate deaminase 1 (AMPD1) is associated with production traits in Chinese cattle
Authors: C.-B. Wei, J.-Q. Wang, F.-Y. Chen, H. Niu and K. Li1,
The objectives of the present study were to detect an 18-bp deletion mutation in the bovine adenosine monophosphate deaminase 1 (AMPD1) gene and analyze its effect on growth traits in 2 Chinese cattle breeds using DNA sequencing and agarose electrophoresis. The five 19-bp polymerase chain reaction products of the AMPD1 gene exhibited 3 genotypes and 2 all.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.6
- DOI:
- 10.4238/2015.February.6.6
Association of MEF2A gene 3'UTR mutations with coronary artery disease
Authors: X.C. Huang and W. Wang
Association of variants in the myocyte enhancer factor 2A (MEF2A) gene and the risk of coronary artery disease (CAD) has drawn much attention but remains controversial. We hypothesized that the 3'-untranslated region (3'-UTR) of this gene could harbor functionally relevant nucleotide changes. Here, we assessed the association between single nucleotide pol.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.20
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.20
Expression of genes associated with the biosynthetic pathways of abscisic acid, gibberellin, and ethylene during the germination of lettuce seeds
Authors: A.C.S. Clemente, R.M. Guimar�£es, D.C. Martins, L.A.A. Gomes,F. Caixeta, R.G.E. Reis and S.D.V.F. Rosa
Seed germination and dormancy are complex phenomena that are controlled by many genes and environmental factors. Such genes are indicated by phytohormones that interact with each other, and may cause dormancy or promote seed germination. The objective of this study was to investigate gene expression associated with the biosynthetic pathways of abscisic ac.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.3
- DOI:
- 10.4238/2015.May.11.3
Genetic diversity and taxonomic status of Pinus tabulaeformis f. shekanensis revealed by ISSR markers
Authors: Z.-H. Liu, Q. Xie and Z.-Q. Li
Pinus tabulaeformis f. shekanensis is a rare taxon endemic in the Ziwuling Loess Plateau, of which only one population is known. Inter-simple sequence repeat molecular markers were employed to compare the taxon’s genetic diversity with its 4 nearest wild relatives (P. tabulaeformis, P. tabulaeformis var. mukdensis, P. massoniana, and P. henryi) to a.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.7
- DOI:
- 10.4238/2015.February.6.7