Gene
Transcriptional analysis of atrial and ventricular muscles from rats
Authors: Y. Zhi3*, Z. Cao2*, Q.H. Li1, X.L. Li1, Y. Sun1, T. Zhang1 and Q. Zhang1
Previous studies have used microarray technology to explore gene expression differences between the atrium and the ventricle. However, selection criteria for the differentially expressed genes (DEGs) based only on either the fold change or the P value in these studies. Here, we aim to further identify the DEGs by setting a P value threshold of 2, which ma.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017330
- DOI:
- 10.4238/gmr.15017330
COL1A1 gene -1997G/T polymorphism and risk of osteoporosis in postmenopausal women: a meta-analysis
Authors: K.H. Yu, J. Tang, C.Q. Dai, Y. Yu and J.J. Hong
Studies investigating the association between the COL1A1 gene -1997G/T polymorphism and the risk of osteoporosis in postmenopausal women have reported conflicting results. We performed a meta-analysis based on the evidence currently available from the literature to make a more precise estimation of this relationship. We conducted searches of the published.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.11
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.11
Population genetic analysis and trichothecene profiling of Fusarium graminearum from wheat in Uruguay
Authors: D. Pan1, A. Mionetto1, N. Calero1, M.M. Reynoso2, A. Torres2 and L. Bettucci1
Fusarium graminearum sensu stricto (F. graminearum s.s.) is the major causal agent of Fusarium head blight of wheat worldwide, and contaminates grains with trichothecene mycotoxins that cause serious threats to food safety and animal health. An important aspect of managing this pathogen and reducing mycotoxin contamination of wheat is knowledge regarding .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017270
- DOI:
- 10.4238/gmr.15017270
Association of interleukin-8 gene polymorphisms in HIV patients with opportunistic infections in Limpopo Province, South Africa
Authors: G.A. Dzhivhuho1, T.C. Nangammbi2 and A. Samie3
Opportunistic infections (OIs) are common among human immunodeficiency virus (HIV) patients; however, genetic susceptibility to these infections has not been studied. Recent studies have shown that interleukin-8 (IL-8) A/T genotype carriers are more susceptible to a variety of diseases. In this study, we showed the effects of IL-8 gene polymorphisms on OI.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017466
- DOI:
- 10.4238/gmr.15017466
Chromosome heteromorphisms are more frequent in couples with recurrent abortions
Authors: H. Akbas H. �°si D. Oral A. Turky�±lmaz S. Kalkanl�±-Ta�� S. Simsek M. Balkan M.N. Sakar M. Fidanboy M.N. Alp T. Budak
Chromosomal heteromorphism is considered a variant of a normal karyotype, but it is more frequent in couples with repeated miscarriages. We investigated chromosomal heteromorphism in couples with repeated miscarriages in comparison with a control group. A total of 455 couples who applied to our genetic diagnosis laboratory in Diyarbakir, Turkey, were evaluat.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.1
- DOI:
- 10.4238/2012.November.12.1
E2F, HSF2, and miR-26 in thyroid carcinoma: bioinformatic analysis of RNA-sequencing data
Authors: J.C. Lu and Y.P. Zhang
In this study, we examined the molecular mechanism of thyroid carcinoma (THCA) using bioinformatics. RNA-sequencing data of THCA (N = 498) and normal thyroid tissue (N = 59) were downloaded from The Cancer Genome Atlas. Next, gene expression levels were calculated using the TCC package and differentially expressed genes (DEGs) were identified using the ed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017576
- DOI:
- 10.4238/gmr.15017576
Analysis of imprinted messenger RNA expression in deceased transgenic cloned goats
Authors: R.X. Jia, Z.R. Zhou, G.M. Zhang, L.Z. Wang, Y.X. Fan, Y.J. Wan, Y.L. Zhang,Z.Y. Wang and F. Wang
Genomic imprinting is an important epigenetic mechanism that has vital effects on fetal growth and development. We observed the differences in four tissues (heart, spleen, liver, and kidney) from dead transgenic cloned goats using hematoxylin and eosin (H&E) staining. Eight imprinted genes in the tissues of dead transgenic cloned and normal goats were.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017455
- DOI:
- 10.4238/gmr.15017455
Microsporogenesis in inbred line of popcorn (Zea mays L.)
Authors: Ricci GCL, Silva N, Pagliarini MS and Scapim CA
Endogamy places genes for several characteristics in homozygosis, which include those related to meiosis causing abnormalities that may impair gamete viability. An original population (S0) of popcorn (CMS-43) produced by Embrapa Maize and Sorghum was self-pollinated for seven years, generating inbred lines (S1 to S7). Conventi.. Read More»
- Genet. Mol. Res. 6(4):
Development and characterization of microsatellite loci in Megalonibea fusca
Authors: Z.B. Li, Q.H. Li, Y.F. Ning, J.B. Shangguan, G. Dai, L.N. Chen, Y.Y. Cao and X.J. Chen
Megalonibea fusca is a commercially important large edible fish. In this study, the first set of 10 polymorphic microsatellite loci for M. fusca was developed and characterized. The number of alleles per locus ranged from two to five, with the observed and expected heterozygosities ranging from 0.0667 to 0.7667, and from 0.0644 to 0.5828, respectively. Mo.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.22
- DOI:
- 10.4238/2015.May.4.22
Expression profiles of phosphatidylinositol phosphate kinase genes during normal human in vitro erythropoiesis
Authors: T.R. Zaccariotto C. Lanaro D.M. Albuquerque M.N.N. Santos M.A.C. Bezerra F.G.P. Cunha I. Lorand-Metze A.S. Araujo F.F. Costa M.F. Sonati
Phosphatidylinositol phosphate kinases (PIPKs) are enzymes that participate in diverse intracellular signaling pathways. They are classified into 3 functionally distinct subfamilies - PIPKI (a, b, g), PIPKII (a, b, g), and PIPKIII - located in various subcellular compartments. Recently, the PIPKIIa and b-globin genes were found to be overexpressed in reticul.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.3
- DOI:
- 10.4238/2012.November.12.3