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Gene

Animal Genetics   Research Article

Isolation and characterization of new microsatellite markers in the pen shell Atrina pectinata (Pinnidae)

Authors: X.J. Chen Z.B. Li L. Chen Y.Y. Cao Q.H. Li

The pen shell, Atrina pectinata, is a commercially important bivalve species, widely consumed in the Asian Pacific region. We identified 16 new microsatellite makers for A. pectinata using a modified fast isolation by AFLP of sequences containing repeat protocols; 27 individuals were collected from Xiamen to evaluate the degree of polymorphism. The number of.. Read More»

Genet. Mol. Res. 11(3):
2012.May.22.4
DOI:
10.4238/2012.May.22.4
Plant Genetics   Research Article

Expression of metallothionein type 2 and 3 genes in Prosopis glandulosa leaves treated with copper

Authors: C. Michel-Lopez, O. Zapata-P�©rez, D. Gonz�¡lez-Mendoza,O. Grimaldo-Juarez, C. Cece�±a-Duran, O. Tzintzun-Camacho

For a better understanding of the strategies that are used by Prosopis glandulosa in heavy metal tolerance, the present study evaluated the gene expression of three metallothioneins (MTs; PgMt2-1, PgMt2, and PgMt3) in plants exposed to sub-lethal concentrations of copper. The PgMt2-1, PgMt2, and PgMt3 sequences were homologous.. Read More»

Genet. Mol. Res. 16(1):
gmr16019490
DOI:
10.4238/gmr16019490
Human Genetics   Research Article

Association between the interleukin-1�² C-511T polymorphism and periodontitis: a meta-analysis in the Chinese population

Authors: H.F. Wang, F.Q. He, C.J. Xu, D.M. Li, X.J. Sun, Y.T. Chi and W. Guo

The association between the interleukin-1 beta (IL-1β) C-511T (or rs16944) polymorphism and periodontitis remains inconclusive, even though there have been previous studies on this association. To assess the effects of IL-1β C-511T variants on the risk of development of periodontitis, a meta-analysis was performed in.. Read More»

Genet. Mol. Res. 16(1):
gmr16019315
DOI:
10.4238/gmr16019315
Human Genetics   Research Article

Genetic instability and CpG methylation in the 5'-flanking region of the PAI-1 gene in Chinese patients with gastric cancer

Authors: J. Liu X. Li N. Yu Y.-Q. Yang X. Li Z.-Y. Ye J.-C. Li

We explored a possible correlation of genetic instability and CpG methylation in the 5'-flanking region of the PAI-1 gene with clinicopathologic features of gastric cancer in Chinese patients and looked for molecular markers for diagnosing gastric tumor development. Microsatellite instability and loss of heterozygosity of the PAI-1 gene locus D7S515, D7S471 .. Read More»

Genet. Mol. Res. 11(3):
2012.May.18.11
DOI:
10.4238/2012.May.18.11
Plant Genetics   Research Article

Multivariate statistics applied to the reaction of common bean plants to parasitism by Meloidogyne javanica

Authors: L.N.S. Santos, P.D.S. Cabral, G.A.R. Neves, F.R. Alves, M.B. Teixeira1, F.N. Cunha1 N.F. Silva

The availability of common bean cultivars tolerant to Meloidogyne javanica is limited in Brazil. Thus, the present study aimed to evaluate the reactions of 33 common bean genotypes (23 landrace, 8 commercial, 1 susceptible standard and 1 resistant standard) to M. javanica, employing multivariate statistics to discriminate the .. Read More»

Genet. Mol. Res. 16(1):
gmr16019420
DOI:
10.4238/gmr16019420
Plant Genetics   Research Article

A genomic parasite in the evolution of metazoan development

Authors: H.F. Hoenigsberg* and C. Sanabria

It is a challenge to understand how development emerged as a mechanism to dismantle and dismiss the intromission of foreign parasites in order to consolidate a higher-level multicellular unit of selection where more heritable variations in fitness, required for complex organization, can be procured. Levels in biological hierarchy genes, networks of genes,.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr571
DOI:
10.4238/vol8-3gmr571
Animal Genetics   Research Article

Increased expression of a novel splice variant of the complement component 4 (C4A) gene in mastitis-infected dairy cattle

Authors: Y. Yang J.M. Huang Z.H. Ju Q.L. Li L. Zhou R.L. Li J.B. Li F.X. Shi J.F. Zhong C.F. Wang

The complement system helps in the direct lysis of invading pathogens and modulates phagocytic, humoral and cellular immune responses. Complement 4 is a critical component in complement activity and protection against many bacterial pathogens because it is essential to classical and lectin activation pathways. We used reverse transcription and PCR to investi.. Read More»

Genet. Mol. Res. 11(3):
2012.May.18.12
DOI:
10.4238/2012.May.18.12
Plant Genetics   Research Article

Identification of markers tightly linked to tomato yellow leaf curl disease and root-knot nematode resistance by multiplex PCR

Authors: S.X. Chen J.N. Du L.N. Hao C.Y. Wang Q. Chen Y.X. Chang

Seven different commercial F1 hybrids and two F2 populations were evaluated by multiplex PCR to identify plants that are homozygous or heterozygous for Ty-1 and Mi, which confer resistance to tomato yellow leaf curl disease and root-knot nematode, respectively. The Ty-1 and Mi markers were amplified by PCR and identified by digestion of the amplicons with th.. Read More»

Genet. Mol. Res. 11(3):
2012.July.10.4
DOI:
10.4238/2012.July.10.4
Plant Genetics   Research Article

Genetic characterization of green bean (Phaseolus vulgaris) genotypes from eastern Turkey

Authors: G. Sar�±kam�±��1, F. Ya��ar2, M. Bak�±r3, K. Kazan4 and A. Erg�¼l3

Green bean genotypes collected from eastern Turkey were characterized using simple sequence repeat (SSR) markers and morphological traits. Among 12 SSR markers, 10 produced successful amplifications and revealed DNA polymorphisms that were subsequently used to assess genetic relatedness of the genotypes. Based on the number of alleles generated and the pr.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr605
DOI:
10.4238/vol8-3gmr605
Human Genetics   Research Article

Genetic polymorphisms of EGF 5'-UTR and NAT2 857G/A associated with glioma in a case control study of Malaysian patients

Authors: K.A. Muthusamy L.H. Lian N. Vairavan K.H. Chua V. Wara

Studies of genetic mutations that have been used in predicting glioma prognosis have revealed a complex relationship between clinical and genetic factors. Epidermal growth factor (EGF) and the NAT2 gene play a central role in carcinogenesis. An adenine (A) to guanine (G) single nucleotide polymorphism at position 61 in the 5'-untranslated region (5'-UTR) of .. Read More»

Genet. Mol. Res. 11(3):
2012.June.15.7
DOI:
10.4238/2012.June.15.7