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Gene

Human Genetics   Research Article

Red Sindhi cattle in Brazil: population structure and distribution

Authors: J.C.C. Panetto, M.V.G.B. Silva, R.M.H. Leite, M.A. Machado,F.A.T. Bruneli, D.R.L. Reis, M.G.C.D. Peixoto, R.S. Verneque

The Red Sindhi cattle breed was imported to Brazil in small numbers. Nowadays, the herds of this breed are distributed in the Northeast, Southeast and Midwest regions of the country. In this study, DNA samples of animals originating from 15 herds in the Northeast and Southeast regions have been analyzed to obtain the ancestry .. Read More»

Genet. Mol. Res. 16(1):
gmr16019501
DOI:
10.4238/gmr16019501
Human Genetics   Research Article

A clinical study of bone mesenchymal stem cells for the treatment of hepatic fibrosis induced by hepatolenticular degeneration

Authors: D. Zhang

The efficacy of bone marrow mesenchymal stem cell (BMSC) on liver fibrosis in animal has been proven, but a few studies have been made in human body and few such researches in China. This study was designed to investigate the effect of BMSC treatment on hepatic fibrosis induced by hepatolenticular degeneration and the influenc.. Read More»

Genet. Mol. Res. 16(1):
gmr16019352
DOI:
10.4238/gmr16019352
Plant Genetics   Research Article

Comparative analyses of genetic/epigenetic diversities and structures in a wild barley species (Hordeum brevisubulatum) using MSAP, SSAP and AFLP

Authors: X.H. Shan Y.D. Li X.M. Liu Y. Wu M.Z. Zhang W.L. Guo B. Liu Y.P. Yuan

We analyzed genetic diversity and population genetic structure of four artificial populations of wild barley (Hordeum brevisubulatum); 96 plants collected from the Songnen Prairie in northeastern China were analyzed using amplified fragment length polymorphism (AFLP), specific-sequence amplified polymorphism (SSAP) and methylation-sensitive amplified polymor.. Read More»

Genet. Mol. Res. 11(3):
2012.August.17.2
DOI:
10.4238/2012.August.17.2
Human Genetics   Research Article

Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine �²-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes

Authors: F.M. Amaral, A.L. Miranda-Vilela, G.S. Lordelo, I.F. Ribeiro, M.B. Daldegan and C.K. Grisolia

High plasma homocysteine (Hcy) âÂ?Â?âÂ?Â?levels may be responsible for vaso-occlusive episodes and may have acquired and/or genetic causes. This cross-sectional study aimed to investigate the role of methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C) and cystathionine-β-synthase (CBS; T833C/844ins68, G919A) poly.. Read More»

Genet. Mol. Res. 16(1):
gmr16019374
DOI:
10.4238/gmr16019374
Plant Genetics   Research Article

Molecular marker-based genetic diversity analysis of scantly studied Brazilian accessions of a medicinal plant, Morinda citrifolia L. (noni)

Authors: P.N. Bordallo, A.M.R. Monteiro, J.A. Sousa and F.A.S. Arag�£o

Morinda citrifolia L., commonly known as noni, has been used for the treatment of various diseases for over two centuries. It was introduced and widely disseminated in Brazil because of its high market value and ease of adaptation to the soil and climatic conditions of the country. The aim of this study was to estimate the gen.. Read More»

Genet. Mol. Res. 16(1):
gmr16019531
DOI:
10.4238/gmr16019531
Plant Genetics   Research Article

Identification of Magnolia wufengensis (Magnoliaceae) cultivars using phenotypic traits, SSR and SRAP markers: insights into breeding and conservation

Authors: L. Wang, A.H. Xiao, L.Y. Ma, F.J. Chen, Z.Y. Sang and J. Duan

A combination of phenotypic characterization and molecular markers may provide reliable information on new plant varieties and elucidate the conservation status of rare species. Five newly developed Magnolia wufengensis cultivars, an endangered plant species endemic to Hubei Province, China, possess more distinctive phenotypes.. Read More»

Genet. Mol. Res. 16(1):
gmr16019473
DOI:
10.4238/gmr16019473
Plant Genetics   Research Article

Inter- and intra-specific genetic diversity of Iranian yarrow species Achillea santolina and Achillea tenuifolia based on ISSR and RAPD markers

Authors: M. Ebrahimi M. Farajpour M. Rahimmalek

Cultivation and preservation of yarrow has recently attracted wide attention due to its beneficial properties; however, genetic variation of Achillea species is still relatively unknown. We used RAPD and ISSR markers to assess genetic diversity in 16 accessions of yarrow belonging to two species native to Iran. Seven ISSR and nine RAPD primers generated 1.. Read More»

Genet. Mol. Res. 11(3):
2012.August.27.1
DOI:
10.4238/2012.August.27.1
Plant Genetics   Research Article

Molecular characterization of wheat germplasm using microsatellite markers

Authors: S. Ijaz and I.A. Khan

We investigated the genetic diversity of 63 wheat genotypes, composed of 48 accessions and 15 varieties, using 56 polymorphic simple sequence repeat primers. One hundred and eighty-six loci were found, with a mean of 131.26 alleles per locus. Cluster analysis based on microsatellite allelic diversity discrimi­nated the accessions and varieties into di.. Read More»

Genet. Mol. Res. 8(3):
Animal Genetics   Research Article

Population genetic analysis and conservation strategies for redtail shrimp Fenneropenaeus penicillatus using ten microsatellite markers

Authors: Y.Y. Cao, J.B. Shangguan, Z.B. Li

Fenneropenaeus penicillatus, which is on the Red List of Endangered Species for China, is an important shrimp species. However, there is not enough genetic information on F. penicillatus for conservation and management purposes. Ten microsatellite markers were used to analyze the genetic diversity, genetic differentiation, and.. Read More»

Genet. Mol. Res. 16(1):
gmr16019068
DOI:
10.4238/gmr16019068
Human Genetics   Research Article

Frequency of the S65C mutation in the hemochromatosis gene in Brazil

Authors: V.C. Oliveira1,2, F.A. Caxito1, K.B. Gomes3 , A.M. Castro1,V.C. Pardini1 and A.C.S. Ferreira1,2

Development of hereditary hemochromatosis is asso­ciated with the C282Y, H63D or S65C mutations in the hemochro­matosis gene. Though there is extensive knowledge about the former two, there is little information on the mechanism of action and the allelic frequency of the S65C mutation. We examined the prevalence of the S65C mutation of the hemochr.. Read More»

Genet. Mol. Res. 8(3):
vol8-3gmr562
DOI:
10.4238/vol8-3gmr562