Gene
Genetic variability in accessions of the acerola germplasm bank of Universidade Federal Rural de Pernambuco, Brazil
Authors: R.M. Moraes Filho1, L.S.S. Martins2, R.S. Musser3, A.V.V. Montarroyos3 and E.F. Silva2
Brazil is the world’s largest producer of acerola, Malpighia emarginata (Malpighiaceae); the Northeast is responsible for 60% of the national production. The culture of acerola in Brazil has great genetic variability; plantings have high phenotypic diversity and are not very productive, often originating from propagation by seed. We evaluated the ge.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.8
- DOI:
- 10.4238/2013.October.29.8
In vitro effects of Ala16Val manganese superoxide dismutase gene polymorphism on human white blood cells exposed to methylmercury
Authors: T.D. Algarve1, F. Barbisan2, E.E. Ribeiro3, M.M.M.F. Duarte4, M.F. M�¢nica-Cattani1, C.P. Mostardeiro2, A.F. Lenz1 and I.B.M. da Cruz1,2,4
Environmental contamination by methylmercury (MeHg) is an enormous public health problem in world regions such as Amazonia. MeHg toxic effects seem to be influenced by environmental and genetic factors. However, few studies have evaluated the genetic influences of MeHg toxicity in humans. Therefore, the aim of this study was to evaluate the genetic influe.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.7
- DOI:
- 10.4238/2013.October.29.7
Genetic composition of a Brazilian population: the footprint of the Gold Cycle
Authors: E.M. Queiroz1, A.M. Santos2, I.M. Castro2, G.L.L. Machado-Coelho3, A.P.C. C�¢ndido4, T.M. Leite5, R.W. Pereira5 and R.N. Freitas1
Ancestry-informative markers (AIMs) are powerful tools for inferring the genetic composition of admixed populations. In this study, we determined the genetic ancestry of the Ouro Preto (Brazil) population and evaluated the association between ancestry and self-reported skin color. The genetic ancestry of 189 children and adolescents was estimated by genot.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.6
- DOI:
- 10.4238/2013.October.29.6
Evaluation of genetic diversity in Pampus argenteus using SSR markers
Authors: Y. Qin, G. Shi and Y. Sun
In order to evaluate the germplasm resources of Pampus argenteus silver pomfret, the genetic diversity and population structure of 132 silver pomfret samples collected from the three regions (the East China Sea, the Yellow Sea and the Bohai Sea) were examined using 13 polymorphic microsatellite loci. Results indicated a high level of genetic diversity. Th.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.10
- DOI:
- 10.4238/2013.November.22.10
Polymorphism of SREBP1 is associated with beef fatty acid composition in Simmental bulls
Authors: L. Xu*, L.P. Zhang*, Z.R. Yuan, L.P. Guo, M. Zhu, X. Gao, H.J. Gao, J.Y. Li and S.Z. Xu
The sterol regulatory element binding factor 1 gene (SREBP1) plays an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. The objective of this study was to investigate the effect of genetic polymorphisms of SREBP1 on the fatty acid composition of muscle and carcass traits in Simmental bulls and Snow Dragon black ca.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.7
- DOI:
- 10.4238/2013.November.22.7
In-depth pedigree analysis in a large Brazilian Nellore herd
Authors: F.V. Brito1, M. Sargolzaei2,3, J. Braccini Neto1, J.A. Cobuci1, C.M. Pimentel1, J. Barcellos1 and F.S. Schenkel2
A large herd of Nellore cattle was evaluated using in-depth pedigree analyses. Taking into account the incomplete pedigree due to the use of multiple young sires for mating, the average inbreeding coefficient was calculated as 1.73% for the last generation, which was higher than the regular inbreeding coefficient (0.25%). The effective population size was.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.2
- DOI:
- 10.4238/2013.November.22.2
Phylogenetic analysis of substrate-binding subunits in an osmoprotectant system
Authors: T.J.D. Coutinho, N.F. Rodrigues and S.T. Farias
Substrate-binding subunits are important components of the solute importation system, known as the osmoprotectant system, which consists of a membrane protein belonging to the ABC superfamily... Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.1
- DOI:
- 10.4238/2013.November.22.1
Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts
Authors: Y. Hu, X.-X. Tang and H.-Y. He
The aim of this study was to observe the dynamic expression of osteopontin, type I collagen, and osteocalcin genes during the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts and confirm whether BMSCs can differentiate and mature into osteoblasts. A healthy, 2-month-old Altay tailed sheep was obtained, and 10 mL bone marrow was .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.4
- DOI:
- 10.4238/2013.December.11.4
Infertility caused by male partners with genetic defects in Sichuan Province of China
Authors: Q. Quan, T.J. Li, X.P. Ding, J. Wei, L.X. Li and L. Fu
The purpose of this study was to detect chromosomal aberrations and azoospermia factor (AZF) microdeletions in male patients with reproductive problems and to summarize related clinical features to provide reliable information for evaluating prenatal and preimplantation diagnoses. A large cohort of 5083 men with various phenotypes of male infertility was .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.2
- DOI:
- 10.4238/2013.December.11.2
Random regression models using Legendre orthogonal polynomials to evaluate the milk production of Alpine goats
Authors: F.G. Silva, R.A. Torres, L.F. Brito, R.F. Euclydes, A.L.P. Melo,N.O. Souza1, J.I. Ribeiro Jr. and M.T. Rodrigues
The objective of this study was to identify the best random regression model using Legendre orthogonal polynomials to evaluate Alpine goats genetically and to estimate the parameters for test day milk yield. On the test day, we analyzed 20,710 records of milk yield of 667 goats from the Goat Sector of the Universidade Federal de Viçosa. The evaluat.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.1
- DOI:
- 10.4238/2013.December.11.1