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Gene

Bioinformatics   Research Article

An efficient algorithm for finding attractors in synchronous Boolean networks with biochemical applications

Authors: D. Zheng, G. Yang, X. Li, Z. Wang and W.N.N. Hung

Self-organized systems, genetic regulatory systems and other living systems can be modeled as synchronous Boolean networks with stable states, which are also called state-cycle attractors (SCAs). This paper summarizes three classes of SCAs and presents a new efficient binary decision diagram based algorithm to find all SCAs of synchronous Boolean networks.. Read More»

Genet. Mol. Res. 12(4):
2013.October.18.4
DOI:
10.4238/2013.October.18.4
Plant Genetics   Research Article

Genome-wide analysis of the homeodomain-leucine zipper (HD-ZIP) gene family in peach (Prunus persica)

Authors: C.H. Zhang, R.J. Ma, Z.J. Shen, X. Sun, N.K. Korir and M.L. Yu

In this study, 33 homeodomain-leucine zipper (HD-ZIP) genes were identified in peach using the HD-ZIP amino acid sequences of Arabidopsis thaliana as a probe. Based on the phylogenetic analysis and the individual gene or protein characteristics, the HD-ZIP gene family in peach can be classified into 4 subfamilies, HD-ZIP I, II.. Read More»

Genet. Mol. Res. 13(2):
2014.April.8.8
DOI:
10.4238/2014.April.8.8
Plant Genetics   Research Article

Cytogenetic and molecular identification of a wheat-Leymus mollis alien multiple substitution line from octoploid Tritileymus x Triticum durum

Authors: Y.H. Pang, J.X. Zhao, W.L. Du, Y.L. Li, J. Wang, L.M. Wang, J. Wu, X.N. Cheng, Q.H. Yang and X.H. Chen

Leymus mollis (Trin.) Pilger (NsNsXmXm, 2n = 28), a wild relative of common wheat, possesses many traits that are potentially valuable for wheat improvement. In order to exploit and utilize the useful genes of L. mollis, we developed a multiple alien substitution line, 10DM50, from the progenies of octoploid Tritileymus M842-1.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.23.1
DOI:
http://dx.doi.org/10.4238/2014.May.23.1
Human Genetics   Research Article

Prognostic implication of molecular aberrations in cytogenetically normal acute myeloid leukemia patients receiving allogeneic hematopoietic stem cell transplantation

Authors: Y.C. Liu1,2,3*, H.H. Hsiao1,2*, P.M. Lin4, W.C. Yang1,3, C.S. Chang1,2, T.C. Liu1,3, J.F. Hsu1, M.Y. Yang5 and S.F. Lin1,2

Different molecular aberrations can be discriminated into certain prognostic subgroups in cytogenetically normal acute myeloid leukemia (CN-AML) patients but their impact on allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains controversial and studies from Asian populations are lacking. Forty-two adult non-M3 AML patients receiving allo.. Read More»

Genet. Mol. Res. 12(4):
2013.November.11.3
DOI:
10.4238/2013.November.11.3
Medical Genetics   Research Article

Analysis of differentially expressed genes in malignant biliary strictures

Authors: D.C. Qi, B. Wu, S.L. Tao, J. Zhou, H.X. Qian and D. Wang

Microarray data were collected from bile duct samples from subjects with malignant biliary strictures by endoscopic retrograde cholangiopancreatography to screen for key genes associated with this disease. A predicted interaction network was constructed for these genes to interpret their functions. The gene expression dataset .. Read More»

Genet. Mol. Res. 13(2):
2014.April.8.10
DOI:
10.4238/2014.April.8.10
Medical Genetics   Research Article

Electrophoresis and spectrometric analyses of adaptation-related proteins in thermally stressed Chromobacterium violaceum

Authors: I.B. Cordeiro1, D.P. Castro7, P.P.O. Nogueira7, P.C.S. Angelo6, P.A. Nogueira7, J.F.C. Gon�§alves8, A.M.R.F. Pereira9, J.S. Garcia2,3, G.H.M.F. Souza2,4, M.A.Z. Arruda5, M.N. Eberlin2, S. Astolfi-Filho1, E.V. Andrade1 and J.L. L�³pez-Lozano10

Chromobacterium violaceum is a Gram-negative proteobacteria found in water and soil; it is widely distributed in tropical and subtropical regions, such as the Amazon rainforest. We examined protein expression changes that occur in C. violaceum at different growth temperatures using electrophoresis and mass spectrometry. The total number of spots detected .. Read More»

Genet. Mol. Res. 12(4):
2013.October.29.1
DOI:
10.4238/2013.October.29.1
Human Genetics   Research Article

Population variability of Bemisia tabaci (Genn.) in different hosts

Authors: G.E. do Valle, A.L. Louren�§�£o, M.I. Zucchi, J.B. Pinheiro and A.G. de Abreu

The silverleaf whitefly, Bemisia tabaci (Genn.) (Hemiptera: Aleyrodidae), is a cryptic species complex that contains some of the most damaging pests in tropical and subtropical regions. Recent studies have indicated that this complex is composed of at least 24 distinct and morphologically indistinguishable species that mainly differ in their ability to tr.. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.4
DOI:
10.4238/2013.October.17.4
Plant Genetics   Research Article

Reduced genetic diversity in endemic Brazilian Lymania spp (Bromeliaceae) populations and implications for conservation

Authors: V.C.C. Pampon�©t1, T.F. Alves2, R.A. Martinez3, R.X. Corr�ªa1,2 and F.A. Gaiotto1,2

We analyzed the genetic diversity of populations of two sympatric species of Lymania (Bromeliaceae), both endemic to the Atlantic rainforest of southern Bahia (Brazil). Lymania azurea has a restricted occurrence, while Lymania smithii has a wider distribution. Our aim was to provide genetic data to contribute to the design of more efficient conservation s.. Read More»

Genet. Mol. Res. 12(4):
2013.October.10.1
DOI:
10.4238/2013.October.10.1
Bioinformatics   Research Article

Variability analysis of �Persian� acid lime tree selections using agronomic and molecular markers

Authors: M.G. Santos, O.S. Passos, W.S. Soares Filho, E.A. Girardi, A.S. Gesteira and C.F. Ferreira

‘Persian’ acid lime (PAL) is the most important triploid commercial citrus crop planted in the world. Little is known about the genetic variability of the selections used in Brazil. Therefore, 25 genotypes originating from the PAL, and three control species, Citrus sunki, C. limon, and C. aurantiifolia, were assessed using inter-simple sequenc.. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.3
DOI:
10.4238/2013.October.17.3
Medical Genetics   Research Article

Effects of metallothionein-3 and metallothionein-1E gene transfection on proliferation, cell cycle, and apoptosis of esophageal cancer cells

Authors: Z.Q. Tian, Y.Z. Xu, Y.F. Zhang, G.F. Ma, M. He and G.-Y. Wang

Metallothionein (MT)-3 has cell growth inhibitory activity, and is the only currently known MT subtype with unique physiological functions. The expression levels of MT-1E, a subtype of MT-1, were positively correlated with the degree of esophageal cancer malignancy. The present study aimed to investigate the effects of MT-3 and MT-1E gene transfection on .. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.2
DOI:
10.4238/2013.October.17.2