Gene
Estimates of genetic parameters for total milk yield over multiple ages in Brazilian Murrah buffaloes using different models
Authors: R.C. Sesana, F. Baldi, R.R.A. Borquis, A.B. Bignardi, N.A. Hurtado-Lugo, L. El Faro, L.G. Albuquerque and H. Tonhati
The objective of this study was to estimate variance components and genetic parameters for accumulated 305-day milk yield (MY305) over multiple ages, from 24 to 120 months of age, applying random regression (RRM), repeatability (REP) and multi-trait (MT) models. A total of 4472 lactation records from 1882 buffaloes of the Murr.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.7
- DOI:
- 10.4238/2014.April.14.7
Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations
Authors: L.S. Wang, Y. Jiao, Y. Huang, X.Y. Liu, G. Gibson, B. Bennett,K.M. Hamre, D.W. Li, H.Y. Zhao, J. Gelernter, H.R. Kranzler,L.A. Farrer, L. Lu, Y.J. Wang, W.K. Gu
In prior work, congenic strains carrying the DBA/2Igb (D2) region of chromosome 2 (Chr2) for alcohol preference were bred onto a C57BL/6Ibg (B6) background and as predicted were found to reduce voluntary consumption. Subsequently, interval-specific congenic recombinant strains (ISCRS) were generated and also tested. These ISCR.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.9
- DOI:
- 10.4238/2013.November.26.9
Association of the estrogen receptor-�² gene RsaI and AluI polymorphisms with human idiopathic thin endometrium
Authors: A.W. Le, Z.H. Wang, R. Yuan, L.L. Shan, T.H. Xiao, R. Zhuo, Y. Shen
The aim of this study was to investigate the potential correlation between polymorphisms of the estrogen receptor (ER)-β gene (RsaI and AluI) and ethnic Han Chinese human idiopathic thin endometrium. A total of 120 patients with idiopathic thin endometrium and 120 sterility patients with normal endometrium thickness (cont.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.7
- DOI:
- 10.4238/2013.November.26.7
Spermatogenesis in Triatoma melanocephala (Hemiptera: Triatominae)
Authors: K.C.C. Alevi1, P.P. Mendon�§a1, N.P. Pereira1, J.A. Rosa2 and M.T.V. Azeredo-Oliveira1
Triatoma melanocephala is a rare species of Hemiptera. It belonged to the Brasiliensis subcomplex and presents morphological characteristics very close to those of Triatoma vitticeps. We investigated spermatogenesis of T. melanocephala and compared it with that of T. vitticeps in order to determine whether these organisms have similar cytogenetic characte.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.5
- DOI:
- 10.4238/2013.October.24.5
Correlation of SPECT imaging, biochemical parameters and mutation with systolic dysfunction
Authors: D. Alenizi, N.A. Kizilbash, O. Gill, A. Abukanna, S. Malik, A. Badawy
We investigated systolic dysfunction by the use of biochemical laboratory tests and perfusion single-photon emission computed tomography imaging in 32 Pakistani subjects exhibiting symptoms of this disorder. To investigate underlying genetic causes, such as familial hypercholesterolemia, DNA samples from these subjects were sc.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.6
- DOI:
- 10.4238/2013.November.26.6
Expression profile analysis reveals putative prostate cancer-related microRNAs
Authors: H. Song1*, Y. Liu2*, J. Pan3 and S.T. Zhao1
Annotation of prostate cancer (PC) genomes provides a foundation for discoveries that can improve the understanding and treatment of the disease. Therefore, in the present study, we used the Student t-test to identify differentially expressed PC-related mRNAs and microRNAs (miRNAs). Then, we performed interrelated mapping of miRNA target genes between abn.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.4
- DOI:
- 10.4238/2013.October.24.4
Novel association analysis between HLA-DQB1 polymorphisms and rectal cancer based on a cross-validation design
Authors: F.Z. Tong, W.J. Yu, H. Liu
A new study design based on cross-validation of the age at the onset of rectal cancer and the differences between the frequency distributions of relevant genes in 2 groups was developed for identification of disease-related HLA. Patients with rectal cancer were recruited and their age at the time of the first surgery was recor.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.5
- DOI:
- 10.4238/2013.November.26.5
Genetic diversity of locally adapted sheep from Pantanal region of Mato Grosso do Sul
Authors: B.A. Crispim1, A.B. Grisolia1, L.O. Seno2, A.A. Egito3, F.M. Vargas Junior2 and M.R. Souza2
Sheep of the Pantaneiro breed and seven other breeds, raised in the State of Mato Grosso do Sul, Brazil, were genotyped using eight microsatellite loci. The aim of the present study was to determine the genetic variability, phylogenetic relationship, and patterns of gene introgression and miscegenation among the animals surveyed, to obtain information abo.. Read More»
- Genet. Mol. Res. 12(4):
Mendelian inheritance, genetic linkage, and genotypic disequilibrium at nine microsatellite loci of Cariniana legalis (Mart.) O. Kuntze
Authors: E.V. Tambarussi1, R. Vencovsky1, M.L.M. Freitas2 and A.M. Sebbenn3
Cariniana legalis is one of the largest tropical trees with a wide distribution in the Brazilian Atlantic rainforest. We investigated the Mendelian inheritance, genetic linkage, and genotypic disequilibrium at seven microsatellite loci specifically isolated for C. legalis, and at two previously developed heterologous microsatellite loci. Forty to 100 open.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.11.6
- DOI:
- 10.4238/2013.November.11.6
Changes of gene expression profiles across different phases of vascular calcification in rats
Authors: Z.M. Jiang, X.J. Wu, Y. Liu, X.H. Du, S.J. Shen, L.Y. Xu,W.X. Sun
This study investigated the alteration of gene expression profiles in order to gain a deeper understanding into the molecular mechanism involved in different processes of vascular calcification (VC). Sprague Dawley (SD) rats were injected with 300,000 μg/kg vitamin D3 and gavaged with 25 mg/kg nicotine for 8 or 16 weeks to .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.4
- DOI:
- 10.4238/2013.November.26.4