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Gene

Animal Genetics   Research Article

Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens

Authors: B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen

Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling splee.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.32
DOI:
10.4238/2015.December.16.32
Plant Genetics   Research Article

Genetic potential of segregating populations of red beans conducted by the bulk method with selection

Authors: J.A.N. Menezes J�ºnior, J.E.S. Carneiro, V.M.P.S. Menezes and P.C.S. Carneiro

This study evaluated the performance and estimated the genetic potential of segregating populations of red bean. Twenty populations of the second cycle of recurrent selection for red bean breeding at Universidade Federal de Viçosa were advanced to the F5 generation in bulk with selection for grain appearance. Population.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027329
DOI:
10.4238/gmr.15027329
Microbial Genetics   Research Article

Analysis of the beta-globin gene in DNA of suspected thalassemic great apes

Authors: J. Vuch, M.S. Siori, M.P. Bigatti, L. Segat, G. De Fabrizio and S. Crovella

DNA was recovered from teeth of 2 great ape skeletons, Pan troglodytes (Ptr) and Pongo pygmaeus (Ppy), belonging to a 19th-century zoological collection. The skeletons presented morphological alterations possibly associated with β-thalassemia: Ptr had deformation of the calvaria and oro-maxillo-facial bones with porotic hyperostosis and extend.. Read More»

Genet. Mol. Res. 12(2):
2013.May.21.4
DOI:
10.4238/2013.May.21.4
Microbial Genetics   Research Article

Association between IL-1RN gene polymorphisms and susceptibility to ankylosing spondylitis: a large Human Genome Epidemiology review and meta-analysis

Authors: G.X. Jin, J.Z. Duan, W.L. Guo, L. Li, S.Q. Cui and H. Wang

We made a Human Genome Epidemiology review and meta-analysis to examine a possible association between interleukin-1 receptor antagonist (IL-1RN) polymorphisms and susceptibility to ankylosing spondylitis (AS). Studies of IL-1RN polymorphisms and susceptibility to AS were found by searching the Pubmed, Cochrane library, Embase, Web of Science, Springerlin.. Read More»

Genet. Mol. Res. 12(2):
2013.May.21.3
DOI:
10.4238/2013.May.21.3
Plant Genetics   Research Article

Expressed sequence tag-simple sequence repeat-based molecular variance in two Salicornia (Amaranthaceae) populations

Authors: Z.L. Xu, Z. Ali, J.X. Yi, X.L. He, D.Y. Zhang, G.H. Yu, A.A. Khan, I.A. Khan and H.X. Ma

Salicornia spp is one of the most salt-tolerant vascular plants and is native to salt marshes and estuaries. We developed expressed sequence tag derived-simple sequence repeat (EST-SSR) markers for estimating genetic diversity and marker-assisted Salicornia breeding. Six polymorphic EST-SSRs of 40 detected 27 alleles, ranging .. Read More»

Genet. Mol. Res. 10(2):
Plant Genetics   Research Article

Genetic diversity of rhg1 and Rhg4 loci in wild soybeans resistant to soybean cyst nematode race 3

Authors: C.P. Yuan, Y.J. Wang, H.K. Zhao, L. Zhang, Y.M. Wang, X.D. Liu, X.F. Zhong and Y.S. Dong

Over-utilization of germplasms that are resistant to the soybean cyst nematode (SCN) in soybean breeding programs can lead to genetic vulnerability in resistant cultivars. Resistant wild soybean (Glycine soja) is considered an invaluable gene source for increasing the genetic diversity of SCN resistance. In this study, we geno.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027386
DOI:
10.4238/gmr.15027386
Human Genetics   Research Article

Association between the XPG gene Asp1104His polymorphism and lung cancer risk

Authors: B. Zhou, X.M. Hu and G.Y. Wu

It has been suggested that the xeroderma pigmentosum complementation group G (XPG) gene Asp1104His polymorphism is linked to susceptibility to lung cancer. However, the results from the published studies are contradictory rather than conclusive. With this meta-analysis, we aimed to achieve a better understanding of the effects.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027395
DOI:
10.4238/gmr.15027395
Microbial Genetics   Research Article

Influence of the XbaI polymorphism in the estrogen receptor-�± gene on human spermatogenic defects

Authors: J. Meng, X. Mu and Y.M. Wang

Polymorphisms of estrogen receptor (ER) genes have been implicated in male infertility, but studies of this association have produced conflicting results. The present study was conducted to examine whether polymorphisms within the ERα and ERβ genes are susceptibility factors for human male idiopathic infertility in Chinese men. We investigated .. Read More»

Genet. Mol. Res. 12(2):
2013.June.11.1
DOI:
10.4238/2013.June.11.1
Human Genetics   Research Article

Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia

Authors: F. Richeti, C. Kochi, M.N. Rocha, C. Santâ��Anna Corr�ªa, R. Lazzarini, R.M. Guazzelli, R.F. Mendon�§a, M.R. Melo and C.A. Longui

Normal testosterone levels are frequently observed in women with androgenetic alopecia (AGA), suggesting the involvement of androgen sensitivity in this condition. Androgen sensitivity is related to androgen receptor (AR) messenger RNA (mRNA) production in hair follicles and is negatively related to the number of CAG repeats present in exon 1 of the AR ge.. Read More»

Genet. Mol. Res. 12(2):
2013.February.28.19
DOI:
10.4238/2013.February.28.19
Plant Genetics   Short communication

Plasticity of Corynebacterium diphtheriae pathogenicity islands revealed by PCR

Authors: S.C. Soares, F.A. Dorella, L.G.C. Pacheco, R. Hirata Jr., A.L. Mattos-Guaraldi, V. Azevedo and A. Miyoshi

Despite the existence of a vaccine against diphtheria, this disease remains endemic and is reemerging in several regions due to many factors, including variations in genes coding for virulence factors. One common feature of virulence factors is their high concentration in pathogenicity islands (PAIs), very unstable regions acq.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1211
DOI:
10.4238/vol10-2gmr1211