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Gene

Plant Genetics   Research Article

Genetic differentiation in Aspidosperma polyneuron (Apocynaceae) over a short geographic distance as assessed by AFLP markers

Authors: J.O. Damasceno, E.A. Ruas, L.A. Rodrigues, C.F. Ruas, E. Bianchini, J.A. Pimenta3 and P.M. Ruas

Studies on intraspecific variation can contribute to the development of conservation strategies by identifying units of conservation for threatened species. Aspidosperma polyneuron is a tropical tree of seasonal semideciduous forests that is currently endangered and protected because it has been heavily logged for lumber, alth.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1126
DOI:
10.4238/vol10-2gmr1126
Plant Genetics   Research Article

Homology-based cloning and expression analysis of Rf genes encoding PPR-containing proteins in tobacco

Authors: A.M. Ding, F.X. Li, Y.Q. Chen,, P. Zong, X. Qu, D.P. Gong, G.S. Liu and Y.H. Sun

As a model plant, mechanisms of the cytoplasmic male sterility/restoration of fertility (CMS/Rf) system in tobacco are seldom studied. Using Rf gene sequences from other Solanaceae plants and the draft genome of Nicotiana benthamiana, degenerate primers were designed to amplify the cDNA pool of N. tomentosiformis. In total, si.. Read More»

Genet. Mol. Res. 13(1):
2014.March.31.11
DOI:
10.4238/2014.March.31.11
Animal Genetics   Research Article

Genetic and morphological diversity of Moenkhausia oligolepis (Characiformes: Characidae) populations in the tributaries of the Araguaia River, Brazil: implications for taxonomy and conservation

Authors: T.J. Domingos, L.N. Moraes, R.M. Moresco, V.P. Margarido and P.C. Venere

Molecular genetic assessments that consider ecological information, in addition to endogamy levels, genetic diversity, and the genetic differentiation among species and populations, are particularly important for the conservation of biological diversity. Prime candidates for conservation genetic review are those subject to hum.. Read More»

Genet. Mol. Res. 13(3):
2014.September.29.11
DOI:
10.4238/2014.September.29.11
Plant Genetics   Research Article

Development of universal primers for isolating fragments of the LEAFY gene

Authors: L.X. Yu and B. Yan

LEAFY orthologs are found throughout land plants. Degenerate primers were designed for amplifying exon 3 region fragments of the LEAFY gene. Sixteen taxa from different plants were sampled, all of which were successfully isolated, which indicated that this set of primers is universally applicable for all land plants. With the use of this method, there may.. Read More»

Genet. Mol. Res. 12(2):
2013.June.6.1
DOI:
10.4238/2013.June.6.1
Human Genetics   Research Article

Identification of novel DYNC2H1 mutations associated with short rib-polydactyly syndrome type III using next-generation panel sequencing

Authors: L.S. Chen, S.J. Shi, P.S. Zou, M. Ma, X.H. Chen and D.H. Cao

Short rib-polydactyly syndrome type III (SRPS3) is a perinatal lethal skeletal disorder with polydactyly and multisystem organ abnormalities. While ultrasound of the fetus can detect skeletal abnormalities characteristic of SRPS3, the syndrome is often difficult to diagnose before birth. As SRPS3 is an autosomal recessive diso.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028134
DOI:
10.4238/gmr.15028134
Plant Genetics   Research Article

Genetic diversity in wild sweet cherries (Prunus avium) in Turkey revealed by SSR markers

Authors: S. Ercisli, G. Agar, N. Yildirim, B. Duralija, A. Vokurka and H. Karlidag

Wild sweet cherry (Prunus avium) trees are abundant in the northern part of Turkey, including the Coruh Valley. We analyzed 18 wild sweet cherry genotypes collected from diverse environments in the upper Coruh Valley in Turkey to determine genetic variation, using 10 SSR primers. These SSR primers generated 46 alleles; the num.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1196
DOI:
10.4238/vol10-2gmr1196
Human Genetics   Research Article

Matrix metalloproteinase-9 gene polymorphism in hepatocellular carcinoma patients with hepatitis B and C viruses

Authors: A. El Samanoudy, R. Monir, A. Badawy, L. Ibrahim, K. Farag, S. El Baz, D. Alenizi and A. Alenezy

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide. In Egypt, the incidence of HCC has doubled over the last decade. Matrix metalloproteinase-9 (MMP-9) plays a key role in cancer invasion and metastasis by degrading the extracellular matrix and basement membrane barriers. A cytosine (C)/thymidine (T) .. Read More»

Genet. Mol. Res. 13(3):
2014.September.29.15
DOI:
10.4238/2014.September.29.15
Animal Genetics   Research Article

Breeding value accuracy estimates for growth traits using random regression and multi-trait models in Nelore cattle

Authors: A.A. Boligon, F. Baldi, M.E.Z. Mercadante2, R.B. Lobo, R.J. Pereira and L.G. Albuquerque

We quantified the potential increase in accuracy of expected breeding value for weights of Nelore cattle, from birth to mature age, using multi-trait and random regression models on Legendre polynomials and B-spline functions. A total of 87,712 weight records from 8144 females were used, recorded every three months from birth .. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1087
DOI:
10.4238/vol10-2gmr1087
Animal Genetics   Research Article

Phylogenetic study and barcoding of the blood cockle, Tegillarca granosa, found on the west coast of peninsular Malaysia using the COI gene

Authors: S.Y. Chee, M.N. Devakie, M.N. Siti Azizah

Blood cockles are among the most economically important brackish water invertebrates found in Malaysia. However, our knowledge of blood cockle phylogeny and systematics is rudimentary, especially for the species Tegillarca granosa. It is unclear, for instance, whether the cockles occurring on the west coast of peninsular Malay.. Read More»

Genet. Mol. Res. 10(2):
Human Genetics   Research Article

Analyzing the association between XRCC1 c.1804C>A genetic variant and lung cancer susceptibility in the Chinese population

Authors: J.J. Jin, H.Q. Wang, H.P. Kuang, B.B. Kang, Y.H. Liu and J. Wang

Lung cancer is the most common cancer occurring worldwide. The human X-ray repair complementing group 1 (XRCC1) gene is one of the most important candidate genes that influence the susceptibility to lung cancer. The objective of this study was to analyze the potential association between the c.1804C>A genetic variant of XRC.. Read More»

Genet. Mol. Res. 15(2):
gmr.15024661
DOI:
10.4238/gmr.15024661