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Gene

Microbial Genetics   Research Article

Biogeographic pattern of genetic diversity detected by RAPD and ISSR analysis in Gypsophila (Caryophyllaceae) species from Turkey

Authors: M. Korkmaz and N.Y. Dogan

Gypsophila L. is the 3rd-largest genus of Caryophyllaceae in Turkey, a country that includes 60 taxa belonging to 56 species of the 126 recognized in the genus. A total of 35 taxa are endemic to Turkey, with an approximately 60% endemism ratio. In this study, the genetic diversity of 14 Gypsophila species from Turkey was analyzed using random amplificatio.. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.6
DOI:
10.4238/2015.August.3.6
Microbial Genetics   Research Article

Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb

Authors: Y.Q. Jiang, Y.X. Zhu, X.L. Chen, X. Xu, F. Li, H.J. Fu, C.Y. Shen, Y.Y. Lu, Q.J. Zhuang, G. Xu, Y.Y. Cai, Y. Zhang, S.S. Liu, M.Y. Zhu and S.H. Li

We performed a 1-year cluster-randomized field trial to assess the effect of standardized management of chronic obstructivepulmonary disease (COPD) on lung function and quality of life (QOL) measures in patients in China. We used the Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment guidelines and assessed indexes including pulmonary.. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.9
DOI:
10.4238/2015.August.3.9
Microbial Genetics   Research Article

Pdxl and its role in activating Ngn3 and Pax6 to induce differentiation of iPSCs into islet �² cells

Authors: Y. Qin, L. Xiao, X.B. Zhan and H.X. Zhou

The pancreatic and duodenal homeobox factor 1 (Pdx1) protein is the most pivotal transcription factor in the development of islet β cells. This study investigated the role of Pdx1 and its mechanism in differentiating induced pluripotent stem cells (iPSCs) into islet β cells. iPSCs derived from human skin fibroblasts were cultured in vitro and di.. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.12
DOI:
10.4238/2015.August.3.12
Plant Genetics   Research Article

Prediction of industrial tomato hybrids from agronomic traits and ISSR molecular markers

Authors: A.S.T. Figueiredo, J.T.V. Resende, M.V. Faria, P.R. Da-Silva, B.S. Fagundes and R.G.F. Morales

Heterosis is a highly relevant phenomenon in plant breeding. This condition is usually established in hybrids derived from crosses of highly divergent parents. The success of a breeder in obtaining heterosis is directly related to the correct identification of genetically contrasting parents. Currently, the diallel cross is th.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027981
DOI:
10.4238/gmr.15027981
Medical Genetics   Research Article

T174M polymorphism in the angiotensinogen gene and risk of myocardial infarction: ameta-analysis

Authors: P.Y. Hu,Y.W. Wang,X.H. Pang and H.W. Wang

Numerous studies have evaluated the association between the T174M polymorphism in the angiotensinogen (AGT) gene and myocardial infarction (MI) risk. However, the specific association remains controversial because of small sample sizes and varied study designs among different studies. We performed a meta-analysis to assess this correlation. A comprehensiv.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.5
DOI:
http://dx.doi.org/10.4238/2015.April.22.5
Microbial Genetics   Research Article

Characterization of microsatellite markers and their correlations with growth traits in Mandarin fish (Siniperca chuatsi)

Authors: T.L. Yi, L. Fang, X.F. Liang, L.F. Sun, J. Li, X.N. Luo, W.J. Guo, Y.Q. Dou and J. Sun

Mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection for genetic improvement of this species, 100 microsatellite markers identifi ed in previous studies were characterized in the 25 largest and 25 smallest individuals. Twenty polymorphic loci were used to.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.1
DOI:
10.4238/2015.August.7.1
Human Genetics   Research Article

Development and characterization of microsatellite markers for Ulmus chenmoui (Ulmaceae), an endangered tree endemic to eastern China

Authors: Q.F. Geng, J. He, J. Yang, E. Shi, D.B. Wang, W.X. Xu,N. Jeelani Z.S. Wang and H. Liu

Ulmus chenmoui (Ulmaceae) is an endangered tree found on Langya Mountain, eastern China. To better understand the population genetics of U. chenmoui and conserve the species, we developed microsatellite markers. Using a suppression-polymerase chain reaction technique, 74 compound microsatellite primer pairs were designed. Twel.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027985
DOI:
10.4238/gmr.15027985
Microbial Genetics   Research Article

Analysis of genetic diversity identified by amplified fragment length polymorphism marker in hybrid wheat

Authors: M. Ejaz, Z. Qidi, Z. Gaisheng, N. Na, Z. Huiyan and W. Qunzhu

Amplified fragment length polymorphism markers were used to assess genetic diversity in 10 male sterile wheat crop lines (hetero-cytoplasm with the same nucleus) in relation to a restorer wheat line. These male sterile lines were evaluated using 64 amplified fragment length polymorphism primer combinations, and 13 primers produced polymorphic bands, gener.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.2
DOI:
10.4238/2015.August.7.2
Human Genetics   Research Article

Diallelic analysis to obtain cowpea (Vigna unguiculata L. Walp.) populations tolerant to water deficit

Authors: E.V. Rodrigues, K.J. Damasceno-Silva, M.M. Rocha and E.A. Bastos

The purpose of this study was to identify parents and obtain segregating populations of cowpea (Vigna unguiculata L. Walp.) with the potential for tolerance to water deficit. A full diallel was performed with six cowpea genotypes, and two experiments were conducted in Teresina, PI, Brazil in 2011 to evaluate 30 F2 populations .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027996
DOI:
10.4238/gmr.15027996
Microbial Genetics   Research Article

Sex identification based on AMEL gene PCR amplification from blue sheep (Pseudois nayaur) fecal DNA samples

Authors: X. Liu, Y.Y. Yang, X.M. Wang, Z.S. Liu, Z.H. Wang and Y.Z. Ding

The use of noninvasive genetic sampling to identify the sex of wild animals is an extremely valuable and important tool in molecular ecology and wildlife conservation. Sex determination using the amelogenin gene has been conducted in many species because only a single pair of primers is required to amplify both X- and Y-linked alleles. However, this metho.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.13
DOI:
10.4238/2015.August.7.13