Gene
Inheritance of resistance to Pepper yellow mosaic virus in Capsicum baccatum var. pendulum
Authors: C.S. Bento, R. Rodrigues, L.S.A. Gon�§alves, H.S. Oliveira, M.H. Santos, M.C. Pontes and C.P. Sudr�©
We investigated inheritance of resistance to Pepper yellow mosaic virus (PepYMV) in Capsicum baccatum var. pendulum accessions UENF 1616 (susceptible) crossed with UENF 1732 (resistant). Plants from generations P1, P2, F1, F2, BC1:1, and BC1:2 were inoculated and the symptoms were evaluated for 25 days. Subsequently, an area under the disease progress cur.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.10.3
- DOI:
- 10.4238/2013.April.10.3
Isolation and analysis of �±-expansin genes in the tree Anthocephalus chinensis (Rubiaceae)
Authors: K.X. Ouyang, M.Q. Liu, R.Q. Pian, S.S. Liu and X.Y. Chen
Expansins are cell wall-associated proteins that induce wall extension and relax stress by disrupting noncovalent bonds between cellulose microfibrils and cross-linking glycan chains, thereby promoting wall creep. Anthocephalus chinensis is a very fast-growing economically important tree found mainly in South Asia. Sixteen cDNAs, designated AcEXPA1 to AcE.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.10.2
- DOI:
- 10.4238/2013.April.10.2
Sequence analysis of the regulatory region of the TNF-RII gene in Polish Holstein-Friesian cows
Authors: A. Stachura, E. Kaczmarczyk and B. BojarojÃ?Â?-Nosowicz
Tumor necrosis factor receptor type II (TNF-RII) is a surface glycoprotein that can form a complex with TNF-α and participate in the body’s immune response. Functions of TNF-RII are impaired in the pathogenesis of viral diseases. We analyzed sequences in the regulatory region of the TNF-RII gene in cattle. An attempt was also made to identify .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.19
- DOI:
- 10.4238/2013.April.2.19
Association between the rs4753426 polymorphism in MTNR1B with fasting plasma glucose level and pancreatic �²-cell function in gestational diabetes mellitus
Authors: Y. Zhan, C. Li, Q. Gao, J. Chen, S. Yu and S.G. Liu
We investigated the association between rs4753426 single nucleotide polymorphisms in the melatonin receptor 1B (MTNR1B) gene and the risk of developing gestational diabetes mellitus (GDM). A total of 516 gravidas (186 with GDM and 330 non-diabetic controls) were enrolled in the study. Genotype and allele frequencies of rs4753426 in the MTNR1B gene were de.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.3.1
- DOI:
- 10.4238/2015.August.3.1
Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China
Authors: H. Sun, Z.Q. Yang, S.Y. Liu, L. Yu, K. Huang, K.Q. Lin, J.Y. Chu and X.Q. Huang
Hypertension affects one-fifth of the world population. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that correlated with hypertension in large samples. However, the genetic mutations leading to hypertension might differ among various populations, as they have different origins and are subjected to .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.3.2
- DOI:
- 10.4238/2015.August.3.2
Prediction of core cancer genes using a hybrid of feature selection and machine learning methods
Authors: Y.X. Liu, N.N. Zhang, Y. He and L.J. Lun
Machine learning techniques are of great importance in the analysis of microarray expression data, and provide a systematic and promising way to predict core cancer genes. In this study, a hybrid strategy was introduced based on machine learning techniques to select a small set of informative genes, which will lead to improving classification accuracy. Fi.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.3.10
- DOI:
- 10.4238/2015.August.3.10
Attenuated mRNA expression of lipid metabolism genes in primary hepatocytes following lipopolysaccharide treatment in dairy cows
Authors: Y.Y. Wang, H.P. Li, X.J. Wang,Q.D. Jiang,J. Geng,L.F. Wang,Y.J. Guo,W.F. Lu,H.S. Zhu and G.Y. Yang
The influence of ruminal acidosis on ruminal microbiology and metabolite production has received considerable attention, but little is known regarding the systemic manifestations that arise from ruminal acidosis. Lipopolysaccharide (LPS) is released in the gastrointestinal tract upon ingestion of high-grain or high-fat diets, and it has been implicated in.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.21
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.21
Vascular endothelial growth factor +405G/C and -2578C/A polymorphisms and breast cancer risk: a meta-analysis
Authors: Y. Zhang, Y.F. Yu, J.Z. Wang and H. Jia
This study aimed to analyze the association between the 405G/C and -2578C/A polymorphisms of the vascular endothelial growth factor (VEGF) gene and breast cancer risk by meta-analysis. A systematic computerized search of PubMed, Google Scholar, and Web of Science databases was performed to identify relevant publications. After rigorous searching and scree.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.3.14
- DOI:
- 10.4238/2015.August.3.14
Adeno-associated virus-mediated BMP-7 and SOX9 in vitro co-transfection of human degenerative intervertebral disc cells
Authors: X.F. Ren, Z.Z. Diao,Y.M. Xi,Z.H. Qi,S. Ren,Y.J. Liu,D.L. Yang,X. Zhang and S.L. Yuan
Bone morphogenetic protein-7 (BMP-7) and SOX9 are important transcription factors in chondrogenesis. In this study, we examined the biological function of the adeno-associated virus (AAV)-mediated BMP-7 and SOX9 double gene in vitro co-transfection of nucleus pulposus cells of human degenerative intervertebral disc. Human intervertebral disc nucleus pulpo.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.1
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.1
Effects of siRNA-mediated silencing of Sal-like 4 expression on proliferation and apoptosis of prostate cancer C4-2 cells
Authors: K.F. Liu and Y.X. Shan
The aim of this study was to evaluate the effects of small interfering RNA (siRNA)-inhibited expression of the Sal-like 4 (SALL4) gene on the proliferation, colony formation, and apoptosis of prostate cancer C4-2 cells. C4-2 cells were cultured and divided into a si-SALL4 group, a negative control siRNA group, and a blank cont.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027885
- DOI:
- 10.4238/gmr.15027885