Gene
Association of AGTR1 gene A1166C polymorphism with the risk of heart failure: a meta-analysis
Authors: J.A. Zhang, J.R. Li and Y.J. Qiao
The aim of this study was to investigate the correlation between the A1166C polymorphism in the angiotensin II type 1 receptor (AT1R) gene and heart failure (HF) risk using metaâÃ?Â?Ã?Â?analysis. The PubMed database was searched, and data were extracted independently by two reviewers. Odds ratios (ORs) with corresponding 95% confidence intervals (CI.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.26
- DOI:
- 10.4238/2015.August.7.26
Study of nucleolar behavior during spermatogenesis in Martarega brasiliensis (Heteroptera, Notonectidae)
Authors: L.L.V. Pereira, K.C.C. Alevi, F.F.F. Moreira, J.F. Barbosa, E.R. Silistino-Souza, F.C. Silva J�ºnior, T.S. Souza-Firmino, C.A. Banho and M.M. Itoyama
Few cytogenetic studies have been undertaken using aquatic heteropterans and the nucleolar behavior of these insects has been described in only four species, Limnogonus aduncus, Brachymetra albinerva, Halobatopsis platensis, and Cylindrostethus palmaris. The nucleolus is a cellular structure related to biosyntheticactivity and it exhibits a peculiar behav.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.7
- DOI:
- 10.4238/2015.August.7.7
Application of DNA barcoding markers to the identification of Hopea species
Authors: Nguyen T.P. Trang, N.M. Duc, N.V. Sinh and L. Triest
Hopea chinensis (synonym: H. hongayensis) (Dipterocarpaceae) is a threatened species found so far in only two locations: Quang Ninh (Vietnam) and Guangxi (China). The species shares many morphological characteristics with H. mollissima and the two species are often confused. To overcome this problem of identification and to investigate the genetic relatio.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.28
- DOI:
- 10.4238/2015.August.7.28
tRNALeu intron (UAA) of Ficus carica L.: genetic diversity and evolutionary patterns
Authors: G. Baraket,A.B. Abdelkrim and A. Salhi-Hannachi
Cytoplasmic chloroplast DNA was explored to establish genetic relationships among Ficus carica cultivars and elucidate the molecular evolution of the species. The results suggest the occurrence of haplotype and nucleotide diversity. Conserved group I intron sequence motifs were detected and showed a common secondary structure, despite the presence of some.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.11
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.11
Characteristic element of matrix attachment region mediates vector attachment and enhances nerve growth factor expression in Chinese hamster ovary cells
Authors: X.Y. Wang, J.H. Zhang, Q.L. Sun, Z.Y. Yao, B.G. Deng, W.Y. Guo,L. Wang, W.H. Dong, F. Wang, C.P. Zhao and T.Y. Wang
Preliminary studies have suggested that a characteristic element of the matrix attachment region (MAR) in human interferon-β mediates the adhesion of vectors to Chinese hamster ovary (CHO) cells. In this study, we investigated if vector adhesion increased nerve growth factor (NGF) expression in CHO cells. The MAR characteristic element sequence of hu.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.29
- DOI:
- 10.4238/2015.August.7.29
Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study
Authors: S. Kulanuwat, J. Santiprabhob, B. Phonrat, C. Limwongse, A. Tungtrongchitr, N. Chongviriyaphan and R. Tungtrongchitr
Genetic variants of the POMC and PCSK1 genes cause severe obesity among patients in the early stages of childhood. This family-based study analyzed the links between single nucleotide polymorphisms (SNPs) in either the POMC or PCSK1 genes and obesity, as well as obesity-related traits among obese Thai children and their families. The variants rs1042571 an.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.23
- DOI:
- 10.4238/2015.August.7.23
Polymorphisms in the SIRT5 gene and their association with body measurement and ultrasound traits in Qinchuan cattle
Authors: L.S. Gui,H.C. Wang,G.Y. Liu and L.S. Zan
Silent information regulator 5 (SIRT5), a member of the Sirtuin family class III nicotinamide adenine dinucleotide-dependent protein deacetylases, plays an important role in metabolic and aging processes in mammals. We identified 4 single-nucleotide polymorphisms (SNPs) (G22010A, G22052A, G22119T, and G22245C) in the 3' untranslated regions of the SIRT5 g.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.13
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.13
Development and cross-species transferability of unigene-derived microsatellite markers in an edible oil woody plant, Camellia oleifera (Theaceae)
Authors: B.G. Jia, Q. Lin, Y.Z. Feng, X.Y. Hu, X.F. Tan, F.G. Shao and L. Zhang
Camellia oleifera is an important edible oil woody plant in China. Lack of useful molecular markers hinders current genetic research on this tree species. Transcriptome sequencing of developing C. oleifera seeds generated 69,798 unigenes. A total of 6949 putative microsatellites were discovered among 6042 SSRcontaining unigenes. Then, 150 simple sequence .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.33
- DOI:
- 10.4238/2015.June.18.33
Associations of single nucleotide polymorphisms in the Pygo2 coding sequence with idiopathic oligospermia and azoospermia
Authors: S.-Q. Ge, J. Grifin, L.-H. Liu, K.I. Aston, L. Simon, T.G. Jenkins, B.R. Emery and D.T. Carrell
Male infertility is often associated with a decreased sperm count. The Pygo2 gene is expressed in the elongating spermatid during chromatin remodeling; thus impairment in PYGO2 function might lead to spermatogenic arrest, sperm count reduction, and subsequent infertility. The aim of this study was to identify mutations in Pygo2 that might lead to idiopath.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.14
- DOI:
- 10.4238/2015.August.7.14
Genetic polymorphisms and haplotype of hormone-related genes are associated with the risk of breast cancer in Chinese women
Authors: Z. Pan, Z. Fu, Q. Song, W. Cao, W. Cheng and X. Xu
Sex hormones play important roles in breast cancer (BC) development. This study investigated associations between BC risk and hormone-related gene variants in Chinese women. In a cohort of 336 patients with histopathologically confirmed BC and 390 age-matched controls, we genotyped seven single nucleotide polymorphisms (SNPs) .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028640
- DOI:
- 10.4238/gmr.15028640