Gene
Genetic polymorphisms of paraoxonase1 192 and glutathione peroxidase1 197 enzymes in familial Mediterranean fever
Authors: F. ��ktem, H. An�±l, R. S�¼tc�¼ and A.E. Kuybulu
Familial Mediterranean fever (FMF) is an autosomal recessive disorder and is the most frequent of the periodic febrile inflammatory syndromes. The pathogenesis of the disease is not completely understood, even though the FMF gene has been identified. Oxidative stress and inflammation may play a role in the pathogenesis of FMF... Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.7
- DOI:
- 10.4238/2014.April.29.7
Isolation and characterization of microsatellite DNA loci for wild Brassica juncea (Brassicaceae)
Authors: Y. Li1, X.Q. Sun2, Q.Q. Yan2, J.L. Guo2, S. Qiang1, X.L. Song1 and M.M. Li2
Wild Brassica juncea is a widespread weed in China with increasingly great impact on the yield of many crops. This study aimed to develop microsatellite markers for assessing the genetic diversity and population genetic structure of B. juncea, and to provide basic information for biological and chemical control of the weed. The compound microsatellite mar.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.8.1
- DOI:
- 10.4238/2013.November.8.1
Genetic relationship among Labisia pumila (Myrsinaceae) species based on ISSR-PCR
Authors: E. Karimi, H.Z.E. Jaafar, M.A. Aziz, S. Taheri and R. AzadiGonbad
The genus Labisia (Myrsinaceae) is a popular medicinal plant in Malaysia. We examined the genetic relationship among three varieties of L. pumila var. pumila, L. pumila var. alata, L. pumila var. lanceolata and Labisia paucifolia using an ISSR assay. Fifty-eight primers were tested, among which 18 gave reliable polymorphic ban.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.8
- DOI:
- 10.4238/2014.April.29.8
Association of xeroderma pigmentosum group D (Asp312Asn, Lys751Gln) and cytidine deaminase (Lys27Gln, Ala70Thr) polymorphisms with outcome in Chinese non-small cell lung cancer patients treated with cisplatin-gemcitabine
Authors: M. Zhou, Y.J. Ding, Y. Feng, Q.R. Zhang, Y. Xiang and H.Y. Wan
Xeroderma pigmentosum group D (XPD) plays a key role in the repair of DNA and platinum resistance lesions. Cytidine deaminase (CDA) genes determine the velocity of gemcitabine catalysis. This study aimed to investigate the relationship between XPD and CDA genotypes and outcome in non-small lung cancer (NSCLC) patients. We used.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.9
- DOI:
- 10.4238/2014.April.29.9
Sequence variation in the Toxoplasma gondii eIF4A gene among strains from different hosts and geographical locations
Authors: J. Chen, S.F. Fang, D.H. Zhou, Z.Y. Li, G.H. Liu and X.Q. Zhu
Toxoplasma gondii is an opportunistic protozoan parasite that infects a wide range of animals, including humans. The T. gondii eukaryotic translation initiation factor 4A (eIF4A) protein is expressed in the tachyzoite, but its expression is markedly downregulated in the bradyzoite, and it is therefore considered to be associat.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.29.14
- DOI:
- http://dx.doi.org/10.4238/2014.April.29.14
Study of candidate genes for dyslexia in Brazilian individuals
Authors: M.C.C.M. Svidnicki1, C.A. Salgado2, R.F. Lima2, S.M. Ciasca2, R. Secolin3, M.C.A. Pomilio4, P.A. Junqueira4, M.S. Pinto4, M.M. Pereira4 and E.L. Sartorato1
Dyslexia or reading disability (RD) is the most common childhood learning disorder and a significantly heritable trait. Many recent studies have investigated the genetic basis of dyslexia, and several candidate genes have been proposed. Among these, DCDC2 and KIAA0319 have emerged as the strongest candidate genes for dyslexia; however studies have not pro.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.7.10
- DOI:
- 10.4238/2013.November.7.10
A novel nonsense mutation in the sedlin gene (SEDL) causes severe spondyloepiphyseal dysplasia tarda in a five-generation Chinese pedigree
Authors: X.Y. Xia, J. Yu, W.W. Li, N. Li, Q.Y. Wu , X. Zhou, Y.X. Cui and X.J. Li
Spondyloepiphyseal dysplasia tarda (SEDT) is an X-linked recessive osteochondrodysplasia characterized by disproportionately short stature and degenerative joint disease. The objective of this study was to describe a novel nonsense mutation in the sedlin gene (SEDL) causing severe SEDT in a large Chinese pedigree. The clinical.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.29.15
- DOI:
- http://dx.doi.org/10.4238/2014.April.29.15
Genetic diversity of local Yunnan chicken breeds and their relationships with Red Junglefowl
Authors: J.L. Huo, G.S. Wu, T. Chen, H.L. Huo, F. Yuan, L.X. Liu, C.R. Ge and Y.W. Miao
Yunnan is situated in the Southwest China and encompasses regions having high biodiversity, including habitats for several ancestral species of domestic animals such as chicken. Domestic chickens in Yunnan were kept by peoples of varied ethnic and economic backgrounds living in highly varied geographic environments. To identif.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.29.16
- DOI:
- http://dx.doi.org/10.4238/2014.April.29.16
Identification of marker genes in diabetic wounds by DNA microarray study
Authors: T. Ni1, N. Wang1, Z.G. Mao1 and M. Yao1,2
This study aimed to identify marker genes in diabetic wounds using a dataset based on a DNA microarray of dermal lymphatic endothelial cells, and our results provide a basic understanding of diabetic wounds through further study of these differentially expressed genes (DEGs). From the Gene Expression Omnibus database, we downloaded a gene expression micro.. Read More»
- Genet. Mol. Res. 12(4):
- DOI http://dx.doi.org/2013.November.7.9
- DOI:
- DOI http://dx.doi.org/10.4238/2013.November.7.9
Cross-amplification of nonspecific microsatellites markers: a useful tool to study endangered/vulnerable species of southern Andes deer
Authors: J.C. MarÃ?Ân, P. Orozco-terWengel, K. Romero, J.P. VÃ?¡squez, V. Varas and J.A. Vianna
Thirty-nine microsatellite loci that are highly conserved in red deer, sika deer, reindeer, Soay sheep, and other artiodactyls were tested in two vulnerable and endangered Neotropical deer (pudu: Pudu puda and huemul: Hippocamelus bisulcus) with the aim of producing a standardized set of markers that can be used successfully i.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.25.4
- DOI:
- 10.4238/2014.April.25.4