Gene
Recent progress in identification and characterization of loci associated with sex-linked congenital cataract
Authors: D.D. Zhang, J.Z. Du, J. Topolewski and X.M. Wang
Congenital cataract is a common cause of blindness in children; however, its pathogenesis remains unclear. Genetic factors have been shown to play an important role in the pathogenesis of congenital cataract. The current genetic models of congenital cataract include autosomal dominant, autosomal recessive, and sex-linked inheritance. Sex-linked congenital.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038600
- DOI:
- 10.4238/gmr.15038600
Cloning, characterization, expression, and feeding response of thyrotropin receptor in largemouth bass (Micropterus salmoides)
Authors: Y.L. Gao, W. Song, L.L. Jiang, M.X. Mao, C.L. Wang, C.T. Ge and G.Y. Qian
Thyrotropin receptor (TSHR) is a G-protein-coupled receptor that regulates the synthesis, storage, and secretion of thyroid hormones in the thyroid tissue. The aims of the present study were to characterize the full-length TSHR cDNA in largemouth bass (Micropterus salmoides), and to determine the TSHR gene transcription levels in different tissues. In add.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038658
- DOI:
- 10.4238/gmr.15038658
Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis, published in Genet. Mol. Res. 14 (4):13076-13083 (2015)
Authors: Y. Ji and L.Y. Jin
Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis” by Jin et al. (2015) with great interest. The authors searched the literature for data sources to analyze the relationship between interlerukin-6-174G/C and ischemic stroke. Their meticulousness in study selection and.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038939
- DOI:
- 10.4238/gmr.15038939
Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits
Authors: Y.C. Wang, R.R. Jiang, X.T. Kang, Z.J. Li, R.L. Han, J. Geng,J.X. Fu, J.F. Wang and J.P. Wu
ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 gene. Two single nucleotide polymorphisms (SNPs) (rs3157592.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.25.5
- DOI:
- http://dx.doi.org/10.4238/2015.September.25.5
Evaluation of microsatellite loci from libraries derived from the wild diploid �Calcutta 4� and �Ouro� banana cultivars
Authors: P.R.O. Silva, O.N.J. Jesus, S. Creste, A. Figueira, E.P. Amorim and C.F. Ferreira
Microsatellite markers have been widely used in the quantification of genetic variability and for genetic breeding in Musa spp. The objective of the present study was to evaluate the discriminatory power of microsatellite markers derived from ‘Calcutta 4’ and ‘Ouro’ genomic libraries, and to analyze the genetic variability among 30.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.25.9
- DOI:
- http://dx.doi.org/10.4238/2015.September.25.9
Allogeneic hematopoietic stem cell transplantation in children with aplastic anemia
Authors: H.-M. Xue, H.-G. Xu, K. Huang, H.-X. Guo, Y. Li, D.-H. Zhou, S.-L. Huang, J.-P. Fang and C. Chen
The aim of this study was to prospectively investigate the efficacy and safety of fully matched allogeneic hematopoietic stem cell transplants in children with severe aplastic anemia in China. A total of twenty patients with severe aplastic anemia were enrolled in our study. Thirteen cases underwent transplantation with fully human leukocyte antigen (HLA).. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.15
- DOI:
- 10.4238/2015.May.18.15
Confined housing system increased abdominal and subcutaneous fat deposition and gene expressions of carbohydrate response element-binding protein and sterol regulatory element-binding protein 1 in chicken
Authors: Q. Li, X.L. Zhao, E.R. Gilbert, Y.P. Liu, Y. Wang, M.H. Qiu and Q. Zhu
Free-range production system is increasingly being used in poultry breeding and feed production in many countries. The objective of the current experiment was to evaluate the effects of different raising systems on fat-related traits and mRNA levels of liver lipogenesis genes in Erlang Mountainous chicken. Each of 10 birds (91 day old) from caged, indoor-.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.24
- DOI:
- 10.4238/2015.February.6.24
Effect of recombinant human endostatin on the expression of c-Myc and bFGF in mouse gastric cancer cells
Authors: Z.Y. Guo, G.D. Yao, L.P. Fu, Z.G. Fu and B. Hou
The aim of this study was to observe the effects of recombinant human endostatin on the proliferation and apoptosis of mouse gastric cancer cells, and explore some possible mechanisms of recombinant human endostatin inhibition of cancer. A murine gastric cancer xenograft model was established. A total of 20 mice were divided into two groups (control and e.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.17
- DOI:
- 10.4238/2015.May.18.17
Interleukin-10 gene promoter polymorphism and risk of liver cirrhosis
Authors: Y. Liu, M.C. Yu, A.Q. Zhang, Y.B. Wang, K. Jiang and J.H. Dong
We conducted a hospital-based case-control study to assess the association between IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082 A/G polymorphisms and the risk of liver cirrhosis in a Chinese population. This 1:1-matched case-control study included 192 patients from the Chinese PLA General Hospital. Genotypes of IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.1
- DOI:
- 10.4238/2015.February.13.1
Natural variation of rice blast resistance gene Pi-d2
Authors: J.B. Li, Y.D. Sun, H. Liu, Y.Y. Wang, Y.L. Jia and M.H. Xu
Studying natural variation in rice resistance genes of cultivated and wild rice relatives can predict resistance stability to rice blast fungus. In the present study, the protein coding regions of the rice R gene Pi-d2 in 35 rice accessions, including Oryza sativa L. subsp. indica Kato (Aus), indica (IND), temperate japonica (TEJ), tropical japonica (TRJ), a.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.2
- DOI:
- 10.4238/2015.February.13.2