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Gene

Plant Genetics   Short communication

Isolation of microsatellite loci for Rhodiola alsia (Crassulaceae), an important ethno-medicinal herb endemic to the Qinghai-Tibetan plateau

Authors: F.Q. Zhang, S.Y. Lei, Q.B. Gao, G. Khan, R. Xing, H.L. Yang and S.L. Chen

Rhodiola alsia, which has been used widely in traditional Chinese medicine for a considerable time, grows on moist habitats at high altitude near the snow line. Microsatellite loci were developed for R. alsia to investigate its population genetics. In total, 17 polymorphic microsatellites were developed based on ESTs from the Illumina HiSeqTM 2000 platfor.. Read More»

Genet. Mol. Res. 14(2):
2015.May.18.18
DOI:
10.4238/2015.May.18.18
Plant Genetics   Research Article

Genome-wide identification and expression analysis of the CPP-like gene family in soybean

Authors: L. Zhang, H.K. Zhao, Y.M. Wang, C.P. Yuan, Y.Y. Zhang, H.Y. Li, X.F. Yan, Q.Y. Li and Y.S. Dong

Cysteine-rich polycomb-like protein (CPP-like) genes are a group of transcription factors with highly conserved cysteine-rich domains and are widely distributed in animals and plants, but do not present in yeast. Previous studies have shown that members of this family play important roles in the development of reproductive tissue and in the control of cel.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.4
DOI:
10.4238/2015.February.13.4
Human Genetics   Research Article

Lack of association between the aryl hydrocarbon receptor rs2066853 polymorphism and breast cancer: A meta-analysis on Ahr polymorphism and breast cancer

Authors: Y. Li, H.Z. Qin, Q. Song, X.D. Wu and J.H. Zhu

Published data regarding the association between aryl hydrocarbon receptor (Ahr) rs2066853 polymorphism and the risk of breast cancer shows conflicting results. We performed a meta-analysis on 2999 patients and 3050 controls from three related case-control studies to estimate the association between Ahr rs2066853 polymorphism and the risk of breast cancer.. Read More»

Genet. Mol. Res. 14(4):
2015
DOI:
10.4238/2015
Human Genetics   Research Article

Estrogen receptor alpha gene PvuII polymorphism and risk of fracture in postmenopausal women: a meta-analysis

Authors: W. Deng, J.C. Han, L. Chen and W.L. Qi

Numerous studies have evaluated the association between estrogen receptor alpha (ESR1) gene PvuII polymorphism and fracture risk in postmenopausal women. However, the results have been inconsistent. We performed a meta-analysis to examine the association between the ESR1 gene PvuII polymorphism and fracture risk in postmenopausal women. Studies published fro.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.8
DOI:
10.4238/2015.February.13.8
Animal Genetics   Research Article

Molecular cloning and evolutionary analysis of captive forest musk deer bitter taste receptor gene T2R16

Authors: G.J. Zhao, N. Wu, D.Y. Li, D.J. Zeng, Q. Chen, L. Lu, X.L. Feng, C.L. Zhang, C.L. Zheng and H. Jie

Sensing bitter tastes is crucial for most animals because it can prevent them from ingesting harmful food. This process is mainly mediated by the bitter taste receptors (T2R) that are largely expressed in the taste buds. Previous studies have identified some T2R gene repertoires. Marked variation in repertoire size has been noted among species. However, r.. Read More»

Genet. Mol. Res. 14(4):
2015
DOI:
10.4238/2015
Plant Genetics   Research Article

Agrobacterium-mediated transformation of tomato (Solanum lycopersicum L.) using the expansin 10 (CsEXP10) gene

Authors: Y.D. Sun, W.R. Luo, S.Y. Sun and L. Ni

The cucumber expansin 10 (CsEXP10) gene was previously cloned from young cucumber fruits but its role has not been defined. To determine the role of this gene in plant growth and development, a CsEXP10 gene transformation system was established. The open reading frame of the gene was inserted behind the CaMV35S promoter of vector pCAMBIA1301, and the cons.. Read More»

Genet. Mol. Res. 14(4):
2015
DOI:
10.4238/2015
Bioinformatics   Research Article

Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers

Authors: Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers

Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucle.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.2
DOI:
10.4238/2015.May.22.2
Medical Genetics   Research Article

Association between C1GALT1 variants and genetic susceptibility to IgA nephropathy in Uygur

Authors: W.L. Li and C. Lu

Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation. Analyses of serum IgA1 from IgAN patients revealed abnormal galactosylation of the O-linked carbohydrate moieties of IgA that may resu.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.3
DOI:
10.4238/2015.May.22.3
Plant Genetics   Research Article

Molecular phylogenetics of the white-lipped peccary (Tayassu pecari) did not confirm morphological subspecies in northwestern South America

Authors: M. Ruiz-Garc�­a, M. Pinedo-Castro, K. Luengas-Villamil, C. VergaraJ.A. Rodriguez and J.M. Shostell

We sequenced the mitochondrial DNA (mtDNA) control region of 59 peccaries (44 white-lipped peccaries, Tayassu pecari, and 15 collared peccaries, Pecari tajacu). We also genotyped 3 DNA microsatellites from 78 white-lipped peccaries representing the 4 putative morphological subspecies (i.e., spiradens, aequatoris, pecari, and albirostris) present in northw.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.6
DOI:
10.4238/2015.May.22.6
Medical Genetics   Research Article

Relationship between DNA repair gene XPD751 single-nucleotide polymorphisms and prognosis of colorectal cancer

Authors: Y. Dong, J.W. Liu, Y.J. Gao, T. Zhou and Y.M. Chen

We examined the relationships between singlenucleotide polymorphisms (SNPs) in the DNA repair gene XPD751 and the efficacy and time to disease progression (TTP) in colorectal cancer patients after platinum-based chemotherapy. Ninety-eight patients diagnosed with advanced colorectal cancer were subjected to oxaliplatin and 5-fluorouracil combination therap.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.8
DOI:
10.4238/2015.May.22.8