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Gene

Plant Genetics   Research Article

Genetic control of the number of leaves above the ear in maize

Authors: A.I. Freire, K.O.G. Dias, L.B.V. Oliveira, R.S. Nalin, F.L. Guedes and J.C. Souza

In this study, we examined the genetic control of the number of leaves above the first ear in maize. The F2 generations and the backcrosses were obtained from 2 contrasting lines for this trait. All generations were assessed in a completely randomized block design with 2 replications. The number of leaves above the ear was counted when the plants were in .. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.11
DOI:
10.4238/2015.February.13.11
Human Genetics   Research Article

Type II deiodinase polymorphisms and serum thyroid hormone levels in patients with mild cognitive impairment

Authors: M. Luo, X.H. Zhou, T. Zou, K. Keyim and L.M. Dong

We investigated type II deiodinase (DIO2 ) polymorphisms and serum thyroid hormone levels in subjects with mild cognitive impairment (MCI) in a Uygur population. We studied the DIO2 Thr92Ala (rs225014) and ORFa-Gly3Asp (rs12885300) polymorphisms of 129 unrelated MCI cases and 131 matched controls. All subjects were genotyped using SNaPshot SNP genotyping.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.10
DOI:
10.4238/2015.May.22.10
Human Genetics   Research Article

Relationship between polymorphism of SOCS-3 and dyslipidemia in China Xinjiang Uygur

Authors: X.G. Yao, J. Meng, L. Zhou, N. Lin, J. Hong, M. Heizhati and N.F. Li

We investigated the relationship between the polymorphism of SOCS-3 and dyslipidemia of people from Uygur in Xinjiang, China. This cross-sectional study included 1379 participants in a Hetian Xinjiang Uygur population who were 30-70 years of age and were not from interracial marriages of 3 generations; all subjects were genotyped (909 dyslipidemia subject.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.13
DOI:
10.4238/2015.February.13.13
Plant Genetics   Research Article

Genetic analysis of seed-shattering genes in rice using an F3:4 population derived from an Oryza sativa x Oryza rufipogon cross

Authors: S.-J. Kwon, J. Yu, Y.J. Park, J.-H. Son, N.-S. Kim and J.K. Lee

Seed shattering of wild plant species is thought to be an adaptive trait to facilitate seed dispersal. For rice breeding, seed shatter­ing is an important trait for improving breeding strategies, particularly when developing lines use interspecific hybrids and introgression of genes from wild species. We developed F3:4 recombinant inbred lines from an.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.14
DOI:
10.4238/2015.February.13.14
Microbial Genetics   Research Article

Streptomyces ansochromogenes Tur-10 produces a substance with antifungal bioactivity

Authors: N.M. Vasconcelos, J.M. Fontes, M.R.C.R. Lins, G.R.B. Bernardo,J.M. Ara�ºjo and G.M.S. Lima

The increased incidence of fungal infections and the development of drug resistance have led to the search for microorganisms capable of producing bioactive metabolites with antifungal activity. Among these microorganisms, Streptomyces spp are distinguished mainly owing to their potential to secrete bioactive molecules. The aim of this study was to evalua.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.13
DOI:
10.4238/2015.May.22.13
Medical Genetics   Research Article

Lack of association between a common polymorphism of the endothelial lipasegene and early-onset coronary artery disease in a Chinese Han population

Authors: G.J. Cai, G.P. He, Z.Y. Huang, and C.P. Qi

A growing body of evidence suggests that the 584C/T polymorphism in the endothelial lipase (EL) gene contributes to the process of coronary artery disease (CAD). The present study aimed to reveal the potential relationship between the EL 584C/T gene polymorphism and early-onset CAD, CAD severity, and lipid levels in a Chinese .. Read More»

Genet. Mol. Res. 13(1):
2014.February.20.7
DOI:
10.4238/2014.February.20.7
Animal Genetics   Research Article

Phylogenetic relationships of Malaysian monkeys, Cercopithecidae, based on mitochondrial cytochrome c sequences

Authors: B.M. Md-Zain, M. Mohamad, M.A. Ernie-Muneerah, A. Ampeng, A. Jasmi, M. Lakim and M.C. Mahani

Mitochondrial DNA cytochrome c oxidase II (COII) gene sequences of Malaysian Cercopithecidae were examined to ascertain their phylogenetic relationships. Colobinae were represented by the genera Presbytis, Trachypithecus and Nasalis, while the genus Macaca represented Cercopithecinae. DNA amplification and sequencing of the CO.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr942
DOI:
10.4238/vol9-4gmr942
Animal Genetics   Research Article

Genetic analysis of fleece and post-weaning body weight traits in Makuie sheep

Authors: S. Jafari and A. Hashemi

Estimation of genetic parameters is the most important component of an organized selection program. With respect to economic traits, such as wool and mutton traits, production costs can be reduced through a suitable selection program focused on genetic improvement. This study aimed to evaluate genetic parameters of fleece and .. Read More»

Genet. Mol. Res. 13(1):
2014.February.20.9
DOI:
10.4238/2014.February.20.9
Bioinformatics   Research Article

Effects of Thai black sticky rice extract on oxidative stress and lipid metabolism gene expression in HepG2 cells

Authors: W. Sangkitikomol, T. Tencomnao and A. Rocejanasaroj

Anthocyanins, which are found in some food, including Thai black sticky rice, are reported to have health-promoting properties. Oxidative stress plays a major role in the pathogenesis of many degenerative diseases induced by free radicals, such as cardiovascular disease, stroke and cancer. We evaluated the anthocyanin-rich ext.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr912
DOI:
10.4238/vol9-4gmr912
Medical Genetics   Research Article

Blocking the expression of the hepatitis B virus S gene in hepatocellular carcinoma cell lines with an anti-gene locked nucleic acid in vitro

Authors: Y.-B. Deng, H.-J. Qin, Y.-H. Luo, Z.-R. Liang and J.-J. Zou

The aim of this study was to investigate the effects of inhibition of the hepatitis B virus (HBV) S gene by polypurine region locked nucleic acid on viral replication in cells. We designed and synthesized a locked nucleic acid, phosphorothioate oligonucleotides, unmodified oligonucleotides, and unrelated control sequence for the hepatitis B virus S gene p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.14
DOI:
10.4238/2015.May.22.14