Meta-analysis demonstrates lack of an association of microsomal epoxide hydrolase 1 polymorphisms with esophageal cancer risk
Authors: J.J. Hu1*, Z.T. Wang 2* and B. Li1
Epoxide hydrolases metabolize exogenous chemicals, including carcinogens such as polycyclic aromatic hydrocarbons. The relationship between microsomal epoxide hydrolase 1 (EPHX1) polymorphisms and esophageal cancer risk has been investigated in various ethnic populations, but the results have been contradictory. We investigated the association of EPHX1 Ty.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.2
- DOI:
- 10.4238/2013.October.15.2
Genetic divergence among accessions of melon from traditional agriculture of the Brazilian Northeast
Authors: F.A.S. Arag�£o, J. Torres Filho, G.H.S. Nunes, M.A. Queir�³z, P.N. Bordallo, G.S.C. Buso, M.A. Ferreira, Z.P. Costa and F. Bezerra Neto
The genetic divergence of 38 melon accessions from traditional agriculture of the Brazilian Northeast and three commercial hybrids were evaluated using fruit descriptors and microsatellite markers. The melon germplasm belongs to the botanic varieties cantalupensis (19), momordica (7), conomon (4), and inodorus (3), and to eight genotypes that were identif.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.6.3
- DOI:
- 10.4238/2013.December.6.3
Incorporation of genetic marker information in beef cattle breeding programs
Authors: F.M. Rezende
The availability of molecular marker information has turned out to be an opportunity to improve animal breeding programs, by the inclusion of those effects in the estimation of breeding values. Along this perspective, the aims of present research were to compare genetic evaluation models that assume or not marker effects in the estimation of breeding valu.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.30.1
- DOI:
- 10.4238/2013.October.30.1
Relationship between renal injury and the antagonistic roles of angiotensin-converting enzyme (ACE) and ACE2
Authors: C. Ma, H. Xin, X.-Y. Jiang, Y.-X. Wang and Y.-S. Zhang
Angiotensin-converting enzyme 2 (ACE2), a newly discovered carboxypeptidase in the renin-angiotensin system (RAS), antagonizes ACE activity and plays an active role during tissue injury. Yet the mechanism of its action is not well known. Using a streptozotocin (STZ)-induced renal injury rat model, we investigated the relations.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.5
- DOI:
- 10.4238/2014.April.3.5
Oct4 and Sox2 overexpression improves the proliferation and differentiation of bone mesenchymal stem cells in Xiaomeishan porcine
Authors: Y.X. Fan, C.H. Gu, Y.L. Zhang, B.S. Zhong, L.Z. Wang, Z.R. Zhou,Z.Y. Wang, R.X. Jia, F. Wang
Mesenchymal stem cells derived from bone marrow (BMSCs) are a population of self-renewing multipotent cells that are capable of differentiating into various cellular lineages, and are widely employed in tissue engineering and cell therapy. Recently, clinical research involving BMSCs has become increasingly popular. In order to.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.5
- DOI:
- 10.4238/2013.December.2.5
Genetic diversity analysis of oriental river prawn, Macrobrachium nipponense, in Yellow River using microsatellite marker
Authors: H. Qiao1, D. Lv2, S.F. Jiang1, S.M. Sun1, Y.S. Gong1, Y.W. Xiong1, S.B. Jin1 and H.T. Fu1
To assess the genetic status of this species, the genetic diversity of wild Macrobrachium nipponense from seven geographic locations in the Yellow River basin were investigated using 20 polymorphic microsatellite DNA loci. The genetic diversity between populations was indicated by the mean number of alleles per locus and mean observed heterozygosity (H) a.. Read More»
- Genet. Mol. Res. 12(4):
Association between STAT3 gene polymorphisms and ulcerative colitis susceptibility: a case-control study in the Chinese Han population
Authors: L. Wang, Z-T. Wang, H-X. Zhang, J. Liu, S-Y. Lu, R. Fan, J. Zhou, L. Xia, Y-W. Sun, J. Zhong, and Y-Z. Yuan
Ulcerative colitis (UC) is a chronic inflammation of the large intestine. The aim of this study was to investigate the association of two polymorphisms in STAT3 with the risk of UC development in the Chinese Han population. This is a hospital-based case-control study involving 56 UC patients and 274 controls. Genotyping was pe.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.6
- DOI:
- 10.4238/2014.April.3.6
Development and characterization of polymorphic microsatellite markers for Chinese raccoon dog (Nyctereutes procyonoides procyonoides)
Authors: S.Q. Yan, Y.M. Li, C.Y. Bai, X.M. Ding, W.J. Li, J.N. Hou,Z.H. Zhao and J.H. Sun
Chinese raccoon dog (Nyctereutes procyonoides procyonoides) is one of the most important fur-bearing animal species. Information about the genetic background of farmed Chinese raccoon dogs is limited. In this study, 17 polymorphic microsatellite markers were isolated and identified from an (AC)n-microsatellite-enriched library of Chinese raccoon dogs. The.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.6.2
- DOI:
- 10.4238/2013.December.6.2
Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients
Authors: L. Han1,2, X.J. Xu1,2, X.H. Liang1,2 and J. Ma1,2
We investigated the relationships between paraoxonase genetic polymorphisms and essential hypertension in carotid artery atherosclerotic patients. The study included 353 Han participants and 240 Uighur participants from Xinjiang; they were further divided into two groups: essential hypertension with carotid artery atherosclerosis (CAAD group) and essentia.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.30.2
- DOI:
- 10.4238/2013.October.30.2
Diversity of endophytic bacteria in Caragana microphylla grown in the desert grassland of the Ningxia Hui Autonomous Region of China
Authors: J.X. Dai, X.M. Liu and Y.J. Wang1
The diversity of endophytic bacteria in the sand-fixation plant Caragana microphylla was investigated by amplified rDNA restriction analysis and by sequence and phylogenetic comparisons of the 16S rRNA genes. A total of 24, 19, and 17 operational taxonomic units were identified from 16S rDNA libraries of the plant roots, stems.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.7
- DOI:
- 10.4238/2014.April.3.7