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Human Genetics   Research Article

Comparative quantitative trait locus mapping of maize flowering-related traits in an F2:3 and recombinant inbred line population

Authors: Y.H. Liu, Q. Yi, X.B. Hou, X.G. Zhang, J.J. Zhang, H.M. Liu,Y.F. Hu and Y.B. Huang

Flowering-related traits in maize are affected by complex factors and are important for the improvement of cropping systems in the maize zone. Quantitative trait loci (QTLs) detected using different materials and methods usually vary. In the present study, 266 maize (Zea mays) F2:3 families and 301 recombinant inbred lines (RI.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028465
DOI:
10.4238/gmr.15028465
Microbial Genetics   Research Article

Cloning and stress response analysis of the PeDREB2A and PeDREB1A genes in moso bamboo (Phyllostachys edulis)

Authors: H.L. Wu, L. Li, Z.C. Cheng, W. Ge, J. Gao and X.P. Li

Moso bamboo is a large woody bamboo with the highest ecological, economic, and cultural value among all bamboos in Asia. However, environmental stress influences its growth and development and limits its geographic distribution. Therefore, improving its resistance to environmental stress is extremely important. Dehydration responsive element binding (DREB.. Read More»

Genet. Mol. Res. 14(3):
2015.August.28.4
DOI:
10.4238/2015.August.28.4
Human Genetics   Research Article

Detection of protein and DNA damage induced by elevated carbon dioxide and ozone in Triticum aestivum L. using biomarker and comet assay

Authors: E. Abdelhaliem and A.A. Al-Huqail

This study was designed to compare the genetic effects of elevated carbon dioxide (CO2) and ozone (O3), alone or in combination, under irrigated and non-irrigated conditions on proteins and DNA of wheat (Triticum aestivum L.). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), isozymes, random amplified poly.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028736
DOI:
10.4238/gmr.15028736
Human Genetics   Research Article

A clinical study evaluating dendritic and cytokine-induced killer cells combined with concurrent radiochemotherapy for stage IIIB non-small cell lung cancer

Authors: X.P. Zhu, Y.H. Xu, J. Zhou and X.F. Pan

To compare the efficacy of dendritic and cytokine-induced killer cells (DC-CIK) therapy combined with concurrent radiochemotherapy on stage IIIB non-small cell lung cancer. Sixty-three patients with stage IIIB non-small cell lung cancer were randomly divided into the study and control groups. The study group, comprising 30 patients, was treated with DC-CI.. Read More»

Genet. Mol. Res. 14(3):
Plant Genetics   Research Article

Soybean Stem Fly, Melanagromyza sojae (Diptera: Agromyzidae), in the New World: detection of high genetic diversity from soybean fields in Brazil

Authors: J.A. Arnemann, W.T. Tay, T.K. Walsh H. Brier, K. Gordon,F. Hickmann, G. Ugalde and J.V.C. Guedes

Soybean Stem Fly (SSF), Melanagromyza sojae (Zehntner), belongs to the family Agromyzidae and is highly polyphagous, attacking many plant species of the family Fabaceae, including soybean and other beans. SSF is regarded as one of the most important pests in soybean fields of Asia (e.g., China, India), North East Africa (e.g.,.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028610
DOI:
10.4238/gmr.15028610
Human Genetics   Research Article

Roles of microRNA-221/222 in type 2 diabetic patients with post-menopausal breast cancer

Authors: M.Y. Li, S.R. Pan and A.Y. Qiu

The aim of the research was to examine the expression level of microRNA221/222 (miR-221/222) in the serum of patients with type 2 diabetes mellitus (T2DM) who are also diagnosed with post-menopausal breast cancer. We aimed to evaluate the differences in microRNA expression in patients with T2DM alone, patients with post-menopa.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027259
DOI:
10.4238/gmr.15027259
Human Genetics   Research Article

Expression of toll-like receptors in hepatic cirrhosis and hepatocellular carcinoma

Authors: L. Sun, J.J. Dai1, W.F. Hu and J. Wang

Toll-like receptors (TLRs) can specifically identify pathogen-associated molecular patterns (PAMPs) by recognizing structural patterns in diverse microbial molecules, and can provide an effective defense against multiple microbial infectious. A variety of TLRs can be expressed on the surface of liver parenchymal as well as nonparenchymal cells. Kupffer ce.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027419
DOI:
10.4238/gmr.15027419
Human Genetics   Research Article

Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer

Authors: X. Wang and Z.H. Huang

The current study aimed at evaluating the association between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length.. Read More»

Genet. Mol. Res. 14(3):
2015.August.28.7
DOI:
10.4238/2015.August.28.7
Human Genetics   Research Article

Inhibitory effect of microRNA-27b on interleukin 17 (IL-17)-induced monocyte chemoattractant protein-1 (MCP1) expression

Authors: K.D. Huang, Y. Shen, X. Wei, F.Q. Zhang, Y.Y. Liu and L. Ma

We investigated the effect of microRNA-27b (miR-27b), a gene expression regulatory factor, on the expression of monocyte chemoattractant protein-1 (MCP1) stimulated by interleukin 17 (IL-17). After IL-17 had been added to H9C2 cardiomyocytes, an miR-27b mimic was transfected into the H9C2 cells. The mRNA expression levels of m.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027784
DOI:
10.4238/gmr.15027784
Human Genetics   Research Article

Correlation between methylation of the E-Cadherin gene and malignancy of prostate cancer

Authors: S.Q. Zhang, G.Q. Zhang and L. Zhang

Prostate cancer is a common malignant tumor in males with an unclear pathogenic mechanism. As one epigenetic regulation mechanism, DNA methylation of the whole genome and specific gene(s) plays critical roles in pathogenesis, progression, diagnosis, and treatment of prostate cancer. The E-Cadherin gene is involved in cell meta.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028046
DOI:
10.4238/gmr.15028046