Investigation of genes in chronic and acute morphine-treated mice using microarray datasets
Authors: L. Ding, J.L. Zhang, S.H. Yu and L.F. Sheng
Morphine is a psychoactive medication that is used as a standard analgesic treatment to relieve pain in clinics. Many patients rely on chronic or acute treatment of morphine to treat pain. However, morphine is a narcotic and has a reverse effect when inappropriately used. Therefore, it is necessary to study chronic and acute morphine treatment to improve .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.3
- DOI:
- 10.4238/2015.August.28.3
Protein-protein interaction between ezrin and p65 in human breast cancer cells
Authors: R. Tang, F.X. Li, W.F. Shao, Q.S. Wen, X.R. Yu and J.B. Xiong
Our study aimed to investigate the co-localization and protein-protein interactions between ezrin and p65 in human breast cancer cells. Liquid chromatography-mass spectrometry (LCMS) was used to uncover novel protein interactions with ezrin in MDA-MB-231 cells. Endogenous co-immunoprecipitation was used to validate protein-pro.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028334
- DOI:
- 10.4238/gmr.15028334
Comparative quantitative trait locus mapping of maize flowering-related traits in an F2:3 and recombinant inbred line population
Authors: Y.H. Liu, Q. Yi, X.B. Hou, X.G. Zhang, J.J. Zhang, H.M. Liu,Y.F. Hu and Y.B. Huang
Flowering-related traits in maize are affected by complex factors and are important for the improvement of cropping systems in the maize zone. Quantitative trait loci (QTLs) detected using different materials and methods usually vary. In the present study, 266 maize (Zea mays) F2:3 families and 301 recombinant inbred lines (RI.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028465
- DOI:
- 10.4238/gmr.15028465
Cloning and stress response analysis of the PeDREB2A and PeDREB1A genes in moso bamboo (Phyllostachys edulis)
Authors: H.L. Wu, L. Li, Z.C. Cheng, W. Ge, J. Gao and X.P. Li
Moso bamboo is a large woody bamboo with the highest ecological, economic, and cultural value among all bamboos in Asia. However, environmental stress influences its growth and development and limits its geographic distribution. Therefore, improving its resistance to environmental stress is extremely important. Dehydration responsive element binding (DREB.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.4
- DOI:
- 10.4238/2015.August.28.4
Detection of protein and DNA damage induced by elevated carbon dioxide and ozone in Triticum aestivum L. using biomarker and comet assay
Authors: E. Abdelhaliem and A.A. Al-Huqail
This study was designed to compare the genetic effects of elevated carbon dioxide (CO2) and ozone (O3), alone or in combination, under irrigated and non-irrigated conditions on proteins and DNA of wheat (Triticum aestivum L.). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), isozymes, random amplified poly.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028736
- DOI:
- 10.4238/gmr.15028736
A clinical study evaluating dendritic and cytokine-induced killer cells combined with concurrent radiochemotherapy for stage IIIB non-small cell lung cancer
Authors: X.P. Zhu, Y.H. Xu, J. Zhou and X.F. Pan
To compare the efficacy of dendritic and cytokine-induced killer cells (DC-CIK) therapy combined with concurrent radiochemotherapy on stage IIIB non-small cell lung cancer. Sixty-three patients with stage IIIB non-small cell lung cancer were randomly divided into the study and control groups. The study group, comprising 30 patients, was treated with DC-CI.. Read More»
- Genet. Mol. Res. 14(3):
Soybean Stem Fly, Melanagromyza sojae (Diptera: Agromyzidae), in the New World: detection of high genetic diversity from soybean fields in Brazil
Authors: J.A. Arnemann, W.T. Tay, T.K. Walsh H. Brier, K. Gordon,F. Hickmann, G. Ugalde and J.V.C. Guedes
Soybean Stem Fly (SSF), Melanagromyza sojae (Zehntner), belongs to the family Agromyzidae and is highly polyphagous, attacking many plant species of the family Fabaceae, including soybean and other beans. SSF is regarded as one of the most important pests in soybean fields of Asia (e.g., China, India), North East Africa (e.g.,.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028610
- DOI:
- 10.4238/gmr.15028610
Roles of microRNA-221/222 in type 2 diabetic patients with post-menopausal breast cancer
Authors: M.Y. Li, S.R. Pan and A.Y. Qiu
The aim of the research was to examine the expression level of microRNA221/222 (miR-221/222) in the serum of patients with type 2 diabetes mellitus (T2DM) who are also diagnosed with post-menopausal breast cancer. We aimed to evaluate the differences in microRNA expression in patients with T2DM alone, patients with post-menopa.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027259
- DOI:
- 10.4238/gmr.15027259
Expression of toll-like receptors in hepatic cirrhosis and hepatocellular carcinoma
Authors: L. Sun, J.J. Dai1, W.F. Hu and J. Wang
Toll-like receptors (TLRs) can specifically identify pathogen-associated molecular patterns (PAMPs) by recognizing structural patterns in diverse microbial molecules, and can provide an effective defense against multiple microbial infectious. A variety of TLRs can be expressed on the surface of liver parenchymal as well as nonparenchymal cells. Kupffer ce.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027419
- DOI:
- 10.4238/gmr.15027419
Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer
Authors: X. Wang and Z.H. Huang
The current study aimed at evaluating the association between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.7
- DOI:
- 10.4238/2015.August.28.7