Relationship between abnormal NOS expression and the pathogenesis of cerebral aneurysm
Authors: W.S. Liu,H.J. Geng,C.D. Wang,A.J. Li,P.C. Cao,D.K. Wang and G. Li
We sought to investigate the relationship between abnormal expression of nitric oxide synthase (NOS) and pathogenesis of cerebral aneurysm. Brain tissues were collected from 36 patients with cerebral aneurysm confirmed by computer tomography with angiography or neurosurgical therapy. The control group consisted of 25 patients of similar age who had no vas.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.9
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.9
Genetic relationships among wild pomegranate (Punica granatum genotypes from Coruh Valley in Turkey
Authors: S. Ercisli, J. Gadze, G. Agar, N. Yildirim and Y. Hizarci
The pomegranate has been used traditionally in Coruh Valley in Turkey for a long time; fruits are harvested from wild, semi-domesticated and cultivated trees. In the valley, it occurs in general along with olive trees. We sampled 23 wild-grown pomegranate genotypes sampled from different parts of Coruh Valley and compared them.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1155
- DOI:
- 10.4238/vol10-1gmr1155
Prediction model of a joint analysis of beef growth and carcass quality traits
Authors: H.R. Mirzaei, A.P. Verbyla and W.S. Pitchford
A joint growth-carcass analysis was conducted to develop equations for predicting carcass quality traits associated with variation in growth path of crossbred cattle. During a four-year period (1994-1997) of the Australian “Southern Crossbreeding Project”, mature Hereford cows (r = 581) were mated to 97 sires of Je.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1109
- DOI:
- 10.4238/vol10-1gmr1109
Determination of genetic variation among chickpea genotypes and their F1 crosses with RAPD markers
Authors: K. Mahmood, W. Nazeer, M. Naeem, S. Freed, M.A. Khan, G. Abbas, M. Iqbal, A.R. Kulachi, S.A. Sajid, M.A. Sadiq and M. Saleem
The intensity of genetic diversity amongst chickpea genotypes and their crosses is unknown. The current study investigated the genetic diversity of chickpea genotypes and their F1 crosses by using random amplified polymorphic DNA (RAPD) markers. We assessed the variation among 6 chickpea genotypes and 15 F1 crosses with the RAPD markers. The 6 parents and.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.10.1
- DOI:
- 10.4238/2013.April.10.1
Influence of adenosine on preservation of porcine pancreas in islet transplantation
Authors: W.Q. Song, D.Z. Fu, Y. Cheng and Y.F. Liu
Ischemia time during transplantation has greatly restricted the quality and utilization of grafts. To improve the quality of islet transplantation, adenosine was added into the University of Wisconsin (UW) pancreas perfusate to assess its effect on islet yield and function in porcine pancreas. Ten pancreata from donation after cardiac death pigs were obta.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.17
- DOI:
- 10.4238/2015.December.23.17
Study of the methylation patterns of the EGFR gene promoter in non-small cell lung cancer
Authors: Z.Y. Pan, Z.S. Jiang and H.Q. Ouyang
We investigated the methylation state of the epidermal growth factor receptor (EGFR) gene promoter in non-small cell lung cancer (NSCLC) and analyzed its effect on tumor biology. We enrolled 120 patients with NSCLC who had been confirmed by pathologic diagnosis and had been operated on. The methylation states of the EGFR gene promoter were detected and an.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.14
- DOI:
- 10.4238/2015.August.19.14
Association between the XRCC1 Arg399Gln polymorphism and risk of cervical carcinoma: a meta-analysis
Authors: D.Y. Liu, H.C. Liang and X.M. Xiao
Numerous studies have evaluated the association between Arg399Gln polymorphism of DNA repair gene XRCC1 and cervical carcinoma risk. However, the specific association is still controversial. To assess the relationship between XRCC1 Arg399Gln polymorphism and cervical carcinoma, we conducted a comprehensive meta-analysis of 10 case-control studies with 205.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.15
- DOI:
- 10.4238/2015.August.19.15
Analysis of the expression of HMGB-1, CXCL16, miRNA-30a, and TGF-�²1 in primary nephritic syndrome patients and its significance
Authors: W.J. Wang, X.Q. Qu, X.M. Yu, W. Lv and H.Y. Yu
We investigated the expression levels of high-mobility group box protein 1 (HMGB-1), CXC chemokine ligand 16 (CXCL16), microRNA (miRNA)-30a and transforming growth factor b1 (TGF-b1) in primary nephritic syndrome (PNS) patients and the clinical significance of this expression. A total of 56 patients with PNS were included in the PNS group, while 50 health.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.17
- DOI:
- 10.4238/2015.August.19.17
Application of the ERK signaling pathway inhibitor PD98059 in long-term in vivo experiments
Authors: X.Y. Chen, H.Z. Cai, X.Y. Wang, Q.Y. Chen, H. Yang, Y.J. Chen and Y.P. Tang
The aim of this study was to explore methods by which the ERK signaling pathway inhibitor PD98059 (PD) could be used in long-term in vivo experiments. Forty healthy New Zealand rabbits were randomly divided into blank control, model control, PD low-dose, PD high-dose, PD blank, dimethyl sulfoxide (DMSO) control, DMSO blank, and positive control groups. Th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.20
- DOI:
- 10.4238/2015.December.23.20
Vascular endothelial growth factor gene is associated with hypertensive cerebellar hemorrhage and rehabilitative treatment
Authors: Q.S. He, L.F. Yang, W.B. Wang, B. Yuan, L.Y. Zhang and X.J. Guo
Early rehabilitative therapy is important for patients with hypertensive cerebral hemorrhage to improve long-term function of the extremities. Vascular endothelial growth factor (VEGF) is closely associated with the pathogenesis of hypertension. To identify the markers contributing to the genetic susceptibility to hypertensive cerebellar hemorrhage (HCH) .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.18
- DOI:
- 10.4238/2015.August.19.18