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Animal Genetics   Research Article

Prediction model of a joint analysis of beef growth and carcass quality traits

Authors: H.R. Mirzaei, A.P. Verbyla and W.S. Pitchford

A joint growth-carcass analysis was conducted to develop equations for predicting carcass quality traits associated with variation in growth path of crossbred cattle. During a four-year period (1994-1997) of the Australian “Southern Crossbreeding Project”, mature Hereford cows (r = 581) were mated to 97 sires of Je.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1109
DOI:
10.4238/vol10-1gmr1109
Microbial Genetics   Research Article

Determination of genetic variation among chickpea genotypes and their F1 crosses with RAPD markers

Authors: K. Mahmood, W. Nazeer, M. Naeem, S. Freed, M.A. Khan, G. Abbas, M. Iqbal, A.R. Kulachi, S.A. Sajid, M.A. Sadiq and M. Saleem

The intensity of genetic diversity amongst chickpea genotypes and their crosses is unknown. The current study investigated the genetic diversity of chickpea genotypes and their F1 crosses by using random amplified polymorphic DNA (RAPD) markers. We assessed the variation among 6 chickpea genotypes and 15 F1 crosses with the RAPD markers. The 6 parents and.. Read More»

Genet. Mol. Res. 12(2):
2013.April.10.1
DOI:
10.4238/2013.April.10.1
Human Genetics   Research Article

Influence of adenosine on preservation of porcine pancreas in islet transplantation

Authors: W.Q. Song, D.Z. Fu, Y. Cheng and Y.F. Liu

Ischemia time during transplantation has greatly restricted the quality and utilization of grafts. To improve the quality of islet transplantation, adenosine was added into the University of Wisconsin (UW) pancreas perfusate to assess its effect on islet yield and function in porcine pancreas. Ten pancreata from donation after cardiac death pigs were obta.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.17
DOI:
10.4238/2015.December.23.17
Medical Genetics   Research Article

Study of the methylation patterns of the EGFR gene promoter in non-small cell lung cancer

Authors: Z.Y. Pan, Z.S. Jiang and H.Q. Ouyang

We investigated the methylation state of the epidermal growth factor receptor (EGFR) gene promoter in non-small cell lung cancer (NSCLC) and analyzed its effect on tumor biology. We enrolled 120 patients with NSCLC who had been confirmed by pathologic diagnosis and had been operated on. The methylation states of the EGFR gene promoter were detected and an.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.14
DOI:
10.4238/2015.August.19.14
Human Genetics   Research Article

Association between the XRCC1 Arg399Gln polymorphism and risk of cervical carcinoma: a meta-analysis

Authors: D.Y. Liu, H.C. Liang and X.M. Xiao

Numerous studies have evaluated the association between Arg399Gln polymorphism of DNA repair gene XRCC1 and cervical carcinoma risk. However, the specific association is still controversial. To assess the relationship between XRCC1 Arg399Gln polymorphism and cervical carcinoma, we conducted a comprehensive meta-analysis of 10 case-control studies with 205.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.15
DOI:
10.4238/2015.August.19.15
Medical Genetics   Research Article

Analysis of the expression of HMGB-1, CXCL16, miRNA-30a, and TGF-�²1 in primary nephritic syndrome patients and its significance

Authors: W.J. Wang, X.Q. Qu, X.M. Yu, W. Lv and H.Y. Yu

We investigated the expression levels of high-mobility group box protein 1 (HMGB-1), CXC chemokine ligand 16 (CXCL16), microRNA (miRNA)-30a and transforming growth factor b1 (TGF-b1) in primary nephritic syndrome (PNS) patients and the clinical significance of this expression. A total of 56 patients with PNS were included in the PNS group, while 50 health.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.17
DOI:
10.4238/2015.August.19.17
Animal Genetics   Research Article

Application of the ERK signaling pathway inhibitor PD98059 in long-term in vivo experiments

Authors: X.Y. Chen, H.Z. Cai, X.Y. Wang, Q.Y. Chen, H. Yang, Y.J. Chen and Y.P. Tang

The aim of this study was to explore methods by which the ERK signaling pathway inhibitor PD98059 (PD) could be used in long-term in vivo experiments. Forty healthy New Zealand rabbits were randomly divided into blank control, model control, PD low-dose, PD high-dose, PD blank, dimethyl sulfoxide (DMSO) control, DMSO blank, and positive control groups. Th.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.20
DOI:
10.4238/2015.December.23.20
Medical Genetics   Research Article

Vascular endothelial growth factor gene is associated with hypertensive cerebellar hemorrhage and rehabilitative treatment

Authors: Q.S. He, L.F. Yang, W.B. Wang, B. Yuan, L.Y. Zhang and X.J. Guo

Early rehabilitative therapy is important for patients with hypertensive cerebral hemorrhage to improve long-term function of the extremities. Vascular endothelial growth factor (VEGF) is closely associated with the pathogenesis of hypertension. To identify the markers contributing to the genetic susceptibility to hypertensive cerebellar hemorrhage (HCH) .. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.18
DOI:
10.4238/2015.August.19.18
Microbial Genetics   Research Article

De novo assembly, functional annotation, and marker development of Asian pear (Pyrus pyrifolia) fruit transcriptome through massively parallel sequencing

Authors: J.F. Li, Z. Gao, Y.S. Lou, M. Luo, S.R. Song, W.P. Xu, S.P. Wang and C.X. Zhang

This study investigated the Asian pear transcriptome using the RNA-Seq normalized fruit cDNA library to create a transcriptomic resource for unigene and marker discovery. Following the removal of lowquality reads, 127,085,054 trimmed reads were assembled de novo to yield 37,649 non-redundant unigenes with an average length of 599 bp. Alternative splicing .. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.22
DOI:
10.4238/2015.December.23.22
Plant Genetics   Research Article

Genetic variability in agronomic traits of a germplasm collection of hulless barley

Authors: X.Q. Zeng

Germplasm collections represent an important genetic source for crop improvements. In this study, 220 accessions of hulless barley were collected worldwide and their genetic diversity was investigated. Sixteen agronomic traits, including yield and yield components, grain morphology, leaf size, plant height, and lodging resistance, were assessed under fiel.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.23
DOI:
10.4238/2015.December.23.23