All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Microbial Genetics   Research Article

Expression of GFP can influence aging and climbing ability in Drosophila

Authors: R.M.S. Mawhinney and B.E. Staveley

Green fluorescent protein (GFP) is widely used as a reporter transgene in a variety of organisms. Some of the advantages of using GFP include non-invasive visualization of biological events and/or tissues in live specimens and its benign nature. When GFP is expressed throughout the organism, in neurons and eyes, lifespan and c.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1023
DOI:
10.4238/vol10-1gmr1023
Microbial Genetics   Research Article

An outbreak of Candida parapsilosis fungemia among preterm infants

Authors: W. Guo, H.F. Gu, H.G. Zhang, S.B. Chen, J.Q. Wang, S.X. Geng, L. Li, P. Liu, X. Liu, Y.R. Ji, S.W. Li and L. Yang

In this article, we describe the first outbreak of Candida parapsilosis fungemia in our hospital. We examined a cluster of four nosocomial cases of C. parapsilosis fungemia that occurred in the neonatal intensive care unit (NICU) of the Affiliated Xingtai People’s Hospital of Hebei Medical University over a two-week period. We ascertained patient pa.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.13
DOI:
10.4238/2015.December.23.13
Bioinformatics   Research Article

Identification of long non-coding RNA involved in osteogenic differentiation from mesenchymal stem cells using RNA-Seq data

Authors: W.Q. Song, W.Q. Gu, Y.B. Qian, X. Ma, Y.J. Mao and W.J. Liu

The aim of this study was to identify long non-coding RNA (lncRNA) associated with osteogenic differentiation from mesenchymal stem cells (MSCs) using high-throughput RNA sequencing (RNA-Seq) data. RNA-Seq dataset was obtained from the European Bioinformatics Institute (accession No. PRJEB4496), including two replicates each for immortalized mesenchymal s.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.14
DOI:
10.4238/2015.December.23.14
Animal Genetics   Research Article

Phylogenetic relationships of Malayan gaur with other species of the genus Bos based on cytochrome b gene DNA sequences

Authors: M.K.A. Rosli, S.S. Zakaria, S.M.F. Syed-Shabthar, Z.Z. Zainal, M.N. Shukor, M.C. Mahani, O. Abas-Mazni and B.M. Md-Zain

The Malayan gaur (Bos gaurus hubbacki) is one of the three subspecies of gaurs that can be found in Malaysia. We examined the phylogenetic relationships of this subspecies with other species of the genus Bos (B. javanicus, B. indicus, B. taurus, and B. grunniens). The sequence of a key gene, cytochrome b, was compared among 20.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1002
DOI:
10.4238/vol10-1gmr1002
Human Genetics   Research Article

Effects of CD3McAb and rhIL-2 activated bone marrow on the killing and purging of leukemia cells

Authors: X.C. Wei, D.D. Yang, X.R. Han, Y.A. Zhao, Y.C. Li, L.J. Zhang and J.J. Wang

We investigated the roles of CD3McAb and rhIL-2 activated bone marrow in the killing and purging of leukemia cells. Cytotoxicity of activated bone marrow was detected with MTT assay. CFU-GM level in activated bone marrow and the destruction of leukemia cells were measured using the semi-solid cell culture. Immune activation markers in activated bone marro.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.16
DOI:
10.4238/2015.December.23.16
Animal Genetics   Research Article

Differential structure of the intronic promoter of the Bombyx mori A3 actin gene correlated with silkworm sensitivity/resistance to nucleopolyhedrovirus

Authors: J. Tavares, J.P. Bravo, F. Gimenes, Q.A.L. Neto, A. Fiorini and M.A. Fernandez

Previous reports demonstrated that actin is necessary for nucleocapsid transport and viral gene expression during nucleopolyhedrovirus infection of Bombyx mori. The first intron of B. mori A3 actin contains a cryptic promoter that drives expression of a rare isoform. We detected differences in the size and nucleotide compositi.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr978
DOI:
10.4238/vol10-1gmr978
Human Genetics   Research Article

Study of the relationship between the expression of nerve growth factor and aneurysm formation and prognosis

Authors: C.D. Wang,D.K. Wang,P.C. Cao,Z.W. Wang,Z. Wang and Y.T. Wang

We sought to investigate the effect of nerve growth factor (NGF) expression on the formation and prognosis of cerebral aneurysms. Forty-eight cases were selected following a diagnosis of cerebral aneurysm using computed tomography angiography and surgical confirmation. Thirty-four cases of healthy deaths were also chosen. The tissue was tested for NGF exp.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.28.8
DOI:
http://dx.doi.org/10.4238/2015.April.28.8
Medical Genetics   Research Article

RsaI polymorphism of the ER�² gene in women with endometriosis

Authors: R.C.P.C. Silva, I.R. Costa, B.M Bordin, C.T.X. Silva, S.R. Souza, C.L.R. J�ºnior, A.B. Frare and K.K.V.O. Moura

We examined the frequency of RsaI polymorphism of the ERβ gene in 54 patients diagnosed with endometriosis and 46 controls. Peripheral blood was collected from women undergoing laparoscopy with a confirmed diagnosis of endometriosis. Polymorphisms of the ERβ gene and p53 were assessed by PCR and analyzed on 2% agaros.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr940
DOI:
10.4238/vol10-1gmr940
Human Genetics   Research Article

Relationship between abnormal NOS expression and the pathogenesis of cerebral aneurysm

Authors: W.S. Liu,H.J. Geng,C.D. Wang,A.J. Li,P.C. Cao,D.K. Wang and G. Li

We sought to investigate the relationship between abnormal expression of nitric oxide synthase (NOS) and pathogenesis of cerebral aneurysm. Brain tissues were collected from 36 patients with cerebral aneurysm confirmed by computer tomography with angiography or neurosurgical therapy. The control group consisted of 25 patients of similar age who had no vas.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.28.9
DOI:
http://dx.doi.org/10.4238/2015.April.28.9
Plant Genetics   Research Article

Genetic relationships among wild pomegranate (Punica granatum genotypes from Coruh Valley in Turkey

Authors: S. Ercisli, J. Gadze, G. Agar, N. Yildirim and Y. Hizarci

The pomegranate has been used traditionally in Coruh Valley in Turkey for a long time; fruits are harvested from wild, semi-domesticated and cultivated trees. In the valley, it occurs in general along with olive trees. We sampled 23 wild-grown pomegranate genotypes sampled from different parts of Coruh Valley and compared them.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1155
DOI:
10.4238/vol10-1gmr1155