An efficient algorithm for computing fixed length attractors based on bounded model checking in synchronous Boolean networks with biochemical applications
Authors: X.Y. Li,G.W. Yang,D.S. Zheng,W.S. Guo and W.N.N. Hung
Genetic regulatory networks are the key to understanding biochemical systems. One condition of the genetic regulatory network under different living environments can be modeled as a synchronous Boolean network. The attractors of these Boolean networks will help biologists to identify determinant and stable factors. Existing methods identify attractors bas.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.5
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.5
Age-dependent expression of the BPI gene in Sutai piglets
Authors: J. Zhu, C. Zi, Z.C. Wu, L. Liu, X.R. Zheng, X.M. Su, G.Q. Zhu, X.G. Huang, S.L. Wu and W.B. Bao
We compared and analyzed expression of the BPI gene of Sutai piglets ranging from newborn to post-weaning days 8, 18, 30, and 35 by the real-time PCR method, in order to determine if it is involved in protection against disease caused by ETEC F18. There was a significant difference between 18- and 35-day expression in the jejunum. There were also signific.. Read More»
- Genet. Mol. Res. 12(2):
- 2012.April.12.1
- DOI:
- 10.4238/2012.April.12.1
Relationships between transient elastography values and liver fibrosis in chronic liver disease patients with normal or mildly abnormal aminotransferase levels
Authors: Y.P. Zhang, Q. Zhao, Y.Z. Tao, X.R. Niu and L. Rui
This study aimed to evaluate relationships between transient elastography values and liver fibrosis in chronic liver disease patients with normal or mildly abnormal aminotransferase levels. Fifty-six patients were enrolled in the study. Transient elastography and liver biopsy were performed on the same day, and the fibrosis was staged based on the Scheuer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.4
- DOI:
- 10.4238/2015.December.23.4
Mitochondrial DNA diversity of feral pigs from Karukinka Natural Park, Tierra del Fuego Island, Chile
Authors: P. Aravena,O. Skewes and N. Gouin
Control or eradication of exotic species is one of the greatest challenges facing biodiversity and ecosystem conservation. Domestic pigs (Sus scrofa domestica) were released and became feral in the southern region of Chilean Tierra del Fuego Island in the 1900s. Currently, they inhabit part of Karukinka Natural Park, an area of global conservation concern.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.6
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.6
Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer
Authors: D.K. Sun, L. Wang, J.M. Wang and P. Zhang
Dickkopf-1 (DKK-1) is a secreted protein that inhibits Wnt signaling. However, the clinical significance and prognostic value of serum DKK-1 levels have not been previously investigated in bladder cancer in Chinese patients. Blood samples were taken from 94 consecutive patients diagnosed with bladder cancer and 60 healthy control subjects. Serum DKK-1 exp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.5
- DOI:
- 10.4238/2015.December.23.5
Complete mitochondrial genome of the Southern catfish (Silurus meridionalis Chen) and Chinese catfish (S. asotus Linnaeus): Structure, phylogeny, and intraspecific variation
Authors: Q.R. Wang, C. Xu, C.R. Xu and R.J. Wang
The complete mitochondrial genome of the Southern catfish (Silurus meridionalis) and the Chinese catfish (S. asotus), was determined using the long and accurate polymerase chain reaction (LA-PCR) method. The mitochondrial DNA nucleotide sequences of S. meridionalis and S. asotus were compared with those of 47 other catfish species in the same order. The t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.7
- DOI:
- 10.4238/2015.December.23.7
Genetic expression and functional characterization of the RUNX2 gene in human adult bone marrow mesenchymal stem cells
Authors: J.Y. Zhang and L.C. Li
Past studies have revealed the critical role of runt-related transcription factor 2 (RUNX2) in the proliferation and differentiation of mesenchymal stem cells (MSCs). This study therefore aimed to investigate the expression profile of the RUNX2 gene in human bone marrow MSCs and its biological characteristics. Bone marrow MSCs were separated from 12 patie.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.8
- DOI:
- 10.4238/2015.December.23.8
Influence of cyclophilin D protein expression level on endothelial cell oxidative damage resistance
Authors: J.Z. Peng,L. Xue,J. Chen,B.S. Chen and Y.Q. Yang
We examined the influence of cyclophilin-D (CypD) protein expression level on endothelial cell oxidative damage resistance. A model of CypD protein expression or high expression in endothelial cells was established through gene silencing or cloning. The comparable groups were normal endothelial cells cultured in phosphate-buffered solution in liquid handl.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.7
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.7
Cloning of superoxide dismutase from post-harvest Hami melon and quantitative expression analysis before and after disease
Authors: C.H. Shan, F.X. Tang, W. Chen and W.R. Ma
Primers were designed according to the Cu/Zn-SOD gene sequences of cloned Cucurbits plants (cucumbers and watermelons) available in NCBI. Total RNA from Hami melon pulp was used as a template. Following RT-PCR amplification, a 403-bp fragment of the Hami melon Cu/Zn-SOD gene was obtained. According to alignment in BLAST and phylogenetic tree analysis, the.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.10
- DOI:
- 10.4238/2015.December.23.10
Genetic diversity and structure in natural populations of Maytenus truncata Reiss, 1861, a medicinal plant vulnerable to extractivism in Bahia State, Brazil
Authors: R.R. Simplicio, A.M. Waldschmidt, M.B. Amorim, B.S. Almeida and D.G. Pereira
Maytenus truncata (Celastraceae) is a plant species widely used in the treatment of ulcers and tumors. Despite the intensive harvest of native specimens in the State of Bahia, northeastern Brazil, there is no information about the genetic variability or structure of this species. Therefore, the goal of this study was to estimate the genetic diversity and .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.11
- DOI:
- 10.4238/2015.December.23.11