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Cytogenomics   Abstracts

Morphophysiological changes in Malpighian tubule cells during Myrmeleon uniformis development (Neuroptera, Myrmeleontidae)

Authors: C.A. Pacheco and T.L. Silva

The land arthropod secretory system is formed by structures called Malpighian tubules. These tubules are extremely important in insects because they maintain osmoregulation. They are located in the body cavity and are either free or inserted in the rectum wall, forming an arrangement known as the cryptonephridial system. The Malpighian tubules may have mo.. Read More»

Genet. Mol. Res. 12(2):
2013.June.27.1
DOI:
10.4238/2013.June.27.1
Human Genetics   Research Article

Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study

Authors: T. Hasi, L. Hao, L. Yang and X.L. Su

Mongolians are known as heavy drinkers, and they have a high incidence of essential hypertension, which may be an associated pathology. We examined a possible association of essential hypertension and polymorphism of the aldehyde dehydrogenase 2 (ALDH2) gene in Mongolians from Inner Mongolia. Single nucleotide polymorphism rs6.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1056
DOI:
10.4238/vol10-1gmr1056
Human Genetics   Research Article

Anatomy and genetic diversity of two populations of Schinus terebinthifolius (Anacardiaceae) from the Tibagi River basin in Paran�¡, Brazil

Authors: E.A. Ruas, C.F. Ruas, P.S. Medri, C. Medri, M.E. Medri, E. Bianchini, J.A. Pimenta, L.A. Rodrigues and P.M. Ruas

Knowledge of the effects of flooding on plant survival is relevant for the efficiency of management and conservation programs. Schinus terebinthifolius is a tree of economic and ecological importance that is common in northeast Brazil. Flooding tolerance and genetic variation were investigated in two riparian populations of S... Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1028
DOI:
10.4238/vol10-1gmr1028
Human Genetics   Research Article

Clinical application of high-sensitivity cardiac troponin T test in acute myocardial infarction diagnosis

Authors: J.A. Wang, Y. Qin, J. Lv, Y.F. Tian and Y.J. Dong

The aim of this study was to investigate the clinical application of a high-sensitivity cardiac troponin T (hs-cTnT) test in the diagnosis of acute myocardial infarction (AMI). Serum levels of hs-cTnT and cardiac troponin I (cTnI) were detected in 240 AMI patients and 200 healthy donors and used to plot receiver operating characteristic (ROC) curves. A cl.. Read More»

Genet. Mol. Res. 14(4):
2015.December.22.21
DOI:
10.4238/2015.December.22.21
Animal Genetics   Research Article

Acute toxic effects of sonodynamic therapy on hypertrophic scar fibroblasts of rabbit ears

Authors: W. Li,J.F. Fei1,Q. Yang,B.L. Li,C. Lin,Q. Yue and Q.G. Meng

The objective of this study was to observe the acute cytotoxic effects of hematoporphyrin monomethyl ether sonodynamic therapy (HMME-SDT) on hypertrophic scar fibroblasts of rabbit ears. We first assessed the effects of different irradiation times and HMME concentrations on the survival of hypertrophic scar fibroblasts using the 3-(4,5-dimethylthiazol-2-y.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.28.3
DOI:
http://dx.doi.org/10.4238/2015.April.28.3
Human Genetics   Research Article

Efficacy of percutaneous radiofrequency ablation for the treatment of hepatocellular carcinoma

Authors: R.N. Zheng, Z.J. You, S.H. Lin, J. Jia, Y.M. Cai, C. Liu, S. Han and S.M. Wang

In this study, we sought to evaluate the efficacy of transcatheter arterial chemoembolization (TACE) plus radiofrequency ablation (RFA; experimental group) versus RFA treatment (control group) in patients receiving palliative treatment for hepatocellular carcinoma. To summarize the available evidence, we used the Review Manager 5.1 software to perform a m.. Read More»

Genet. Mol. Res. 14(4):
2015.December.22.24
DOI:
10.4238/2015.December.22.24
Bioinformatics   Research Article

A simplified universal genomic DNA extraction protocol suitable for PCR

Authors: T.Y. Wang, L. Wang, J.H. Zhang and W.H. Dong

Conventional genomic DNA extraction protocols need expensive and hazardous reagents for decontamination of phenolic compounds from the extracts and are only suited for certain types of tissue. We developed a simple, time-saving and cost-efficient method for genomic DNA extraction from various types of organisms, using relative.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1055
DOI:
10.4238/vol10-1gmr1055
Animal Genetics   Research Article

Multiple-trait genomic evaluation for milk yield and milk quality traits using genomic and phenotypic data in buffalo in Brazil

Authors: R.R. Aspilcueta-Borquis, F.R. Araujo Neto, D.J.A. Santos, N.A. Hurtado-Lugo, J.A.V. Silva and H. Tonhati

The objective of this study was to compare the multi-trait model using pedigree information and a model using genomic information in addition to pedigree information. We used data from 5896 lactations of 2021 buffalo cows, of which 384 were genotyped using the Illumina Infinium® bovine HD BeadChip, considering seven traits related to milk yield (MY305.. Read More»

Genet. Mol. Res. 14(4):
2015.December.22.27
DOI:
10.4238/2015.December.22.27
Microbial Genetics   Research Article

Effective sample selection for classification of pre-miRNAs

Authors: K. Han

To solve the class imbalance problem in the classification of pre-miRNAs with the ab initio method, we developed a novel sample selection method according to the characteristics of pre-miRNAs. Real/pseudo pre-miRNAs are clustered based on their stem similarity and their distribution in high dimensional sample space, respective.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr1054
DOI:
10.4238/vol10-1gmr1054
Human Genetics   Research Article

Structural modeling and analysis of dengue-mediated inhibition of interferon signaling pathway

Authors: B. Aslam,J. Ahmad,A. Ali,R.Z. Paracha,S.H.K. Tareen,S. Khusro,T. Ahmad,S.A. Muhammad,U. Niazi and V. Azevedo

Dengue virus (DENV) belongs to the family Flaviviridae and can cause major health problems worldwide, including dengue fever and dengue shock syndrome. DENV replicon in human cells inhibits interferon α and β with the help of its non-structural proteins. Non-structural protein 5 (NS5) of DENV is responsible for the proteasome-mediated degradati.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.28.4
DOI:
http://dx.doi.org/10.4238/2015.April.28.4