Effect of lipoic acid combined with paclitaxel on breast cancer cells
Authors: B.J. Li, X.Y. Hao, G.H. Ren and Y. Gong
Breast cancer is the most common gynecologic tumor globally that threatens women’s health. Lipoic acid is a type of antioxidant that can alleviate oxidative stress damage. Studies showed that lipoic acid could inhibit the proliferation of tumor cells in cervical cancer and colon cancer. This paper intends to explore the combined effect of lipoic aci.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.18
- DOI:
- 10.4238/2015.December.22.18
Chromosome stickiness impairs meiosis and influences reproductive success in Panicum maximum (Poaceae) hybrid plants
Authors: C. Pessim,M.S. Pagliarini,N. Silva and L. Jank
Chromosome stickiness has been studied in several species of higher plants and is characterized by sticky clumps of chromatin resulting in sterility. Chromosome stickiness was recorded in Panicum maximum hybrid plants that were cultivated in the field. In the meiocytes affected, chromosomes clumped into amorphous masses that did not orient themselves on t.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.2
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.2
Morphophysiological changes in Malpighian tubule cells during Myrmeleon uniformis development (Neuroptera, Myrmeleontidae)
Authors: C.A. Pacheco and T.L. Silva
The land arthropod secretory system is formed by structures called Malpighian tubules. These tubules are extremely important in insects because they maintain osmoregulation. They are located in the body cavity and are either free or inserted in the rectum wall, forming an arrangement known as the cryptonephridial system. The Malpighian tubules may have mo.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.27.1
- DOI:
- 10.4238/2013.June.27.1
Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study
Authors: T. Hasi, L. Hao, L. Yang and X.L. Su
Mongolians are known as heavy drinkers, and they have a high incidence of essential hypertension, which may be an associated pathology. We examined a possible association of essential hypertension and polymorphism of the aldehyde dehydrogenase 2 (ALDH2) gene in Mongolians from Inner Mongolia. Single nucleotide polymorphism rs6.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1056
- DOI:
- 10.4238/vol10-1gmr1056
Anatomy and genetic diversity of two populations of Schinus terebinthifolius (Anacardiaceae) from the Tibagi River basin in Paran�¡, Brazil
Authors: E.A. Ruas, C.F. Ruas, P.S. Medri, C. Medri, M.E. Medri, E. Bianchini, J.A. Pimenta, L.A. Rodrigues and P.M. Ruas
Knowledge of the effects of flooding on plant survival is relevant for the efficiency of management and conservation programs. Schinus terebinthifolius is a tree of economic and ecological importance that is common in northeast Brazil. Flooding tolerance and genetic variation were investigated in two riparian populations of S... Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1028
- DOI:
- 10.4238/vol10-1gmr1028
Clinical application of high-sensitivity cardiac troponin T test in acute myocardial infarction diagnosis
Authors: J.A. Wang, Y. Qin, J. Lv, Y.F. Tian and Y.J. Dong
The aim of this study was to investigate the clinical application of a high-sensitivity cardiac troponin T (hs-cTnT) test in the diagnosis of acute myocardial infarction (AMI). Serum levels of hs-cTnT and cardiac troponin I (cTnI) were detected in 240 AMI patients and 200 healthy donors and used to plot receiver operating characteristic (ROC) curves. A cl.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.21
- DOI:
- 10.4238/2015.December.22.21
Acute toxic effects of sonodynamic therapy on hypertrophic scar fibroblasts of rabbit ears
Authors: W. Li,J.F. Fei1,Q. Yang,B.L. Li,C. Lin,Q. Yue and Q.G. Meng
The objective of this study was to observe the acute cytotoxic effects of hematoporphyrin monomethyl ether sonodynamic therapy (HMME-SDT) on hypertrophic scar fibroblasts of rabbit ears. We first assessed the effects of different irradiation times and HMME concentrations on the survival of hypertrophic scar fibroblasts using the 3-(4,5-dimethylthiazol-2-y.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.3
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.3
Efficacy of percutaneous radiofrequency ablation for the treatment of hepatocellular carcinoma
Authors: R.N. Zheng, Z.J. You, S.H. Lin, J. Jia, Y.M. Cai, C. Liu, S. Han and S.M. Wang
In this study, we sought to evaluate the efficacy of transcatheter arterial chemoembolization (TACE) plus radiofrequency ablation (RFA; experimental group) versus RFA treatment (control group) in patients receiving palliative treatment for hepatocellular carcinoma. To summarize the available evidence, we used the Review Manager 5.1 software to perform a m.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.24
- DOI:
- 10.4238/2015.December.22.24
A simplified universal genomic DNA extraction protocol suitable for PCR
Authors: T.Y. Wang, L. Wang, J.H. Zhang and W.H. Dong
Conventional genomic DNA extraction protocols need expensive and hazardous reagents for decontamination of phenolic compounds from the extracts and are only suited for certain types of tissue. We developed a simple, time-saving and cost-efficient method for genomic DNA extraction from various types of organisms, using relative.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1055
- DOI:
- 10.4238/vol10-1gmr1055
Multiple-trait genomic evaluation for milk yield and milk quality traits using genomic and phenotypic data in buffalo in Brazil
Authors: R.R. Aspilcueta-Borquis, F.R. Araujo Neto, D.J.A. Santos, N.A. Hurtado-Lugo, J.A.V. Silva and H. Tonhati
The objective of this study was to compare the multi-trait model using pedigree information and a model using genomic information in addition to pedigree information. We used data from 5896 lactations of 2021 buffalo cows, of which 384 were genotyped using the Illumina Infinium® bovine HD BeadChip, considering seven traits related to milk yield (MY305.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.27
- DOI:
- 10.4238/2015.December.22.27