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Human Genetics   Research Article

New record and cytogenetic analysis of Psammolestes tertius Lent & Jurberg, 1965 (Hemiptera, Reduviidae, Triatominae) from Bahia State, Brazil

Authors: J. Oliveira, K.C.C. Alevi, E.O.L. Fonseca, O.M.F. Souza,C.G.S. Santos, M.T.V. Azeredo-Oliveira and J.A. da Rosa

This paper reports on the first occurrence of Psammolestes tertius in the Chapada Diamantina region, located in the city of Seabra, Bahia State, in northeastern Brazil. Following an active search, 24 P. tertius specimens were collected from Phacellodomus rufifrons (rufous-fronted thornbird) nests. The insects did not present a.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028004
DOI:
10.4238/gmr.15028004
Human Genetics   Research Article

Molecular markers located on the DGAT1, CAST, and LEPR genes and their associations with milk production and fertility traits in Holstein cattle

Authors: R. Hill, A. Canal, K. Bondioli, R. Morell and M.D. Garcia

The objective of the present study was to investigate single nucleotide polymorphisms (SNPs) located in three candidate genes previously reported to have effects on fertility and milk production traits in a population of 123 Holstein cows. The milk production traits evaluated included lifetime averages of milk yield, protein c.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017794
DOI:
10.4238/gmr.15017794
Cytogenomics   Research Article

Polymorphisms of the angiotensin II type 1 receptor gene affect antihypertensive response to angiotensin receptor blockers in hypertensive Chinese

Authors: H.T. Gong, X.L. Ma, B.X. Chen, X.Y. Xu, Q. Li, C.X. Guo and F.H. Du

The renin-angiotensin-aldosterone system plays a key role in regulating blood pressure by maintaining vascular tone and the water/sodium balance. Many antihypertensive drugs target the renin-angiotensin-aldosterone system, but the effect differs considerably among hypertensive patients. We investigated whether genetic variants of the angiotensin II type 1.. Read More»

Genet. Mol. Res. 12(2):
2013.June.21.2
DOI:
10.4238/2013.June.21.2
Human Genetics   Research Article

APOA5 polymorphisms associated with lipid metabolism in Brazilian children and adolescents

Authors: E. De Fran�§a, D.S.B.S. Silva, T.F.C. Silva, C.L. Dornelles, J.G. Alves and C.S. Alho

Single nucleotide polymorphisms in the APOA5 gene have been studied for their association with metabolic syndrome. Thus, elucidating the effect of the mechanism involved in APOA5 gene polymorphisms on lipid metabolism is of great importance. In this study we aimed to determine the allelic and genotypic frequencies of -1131T>C, Ser19Trp, and intergenic .. Read More»

Genet. Mol. Res. 15(1):
gmr.15017809
DOI:
10.4238/gmr.15017809
Microbial Genetics   Research Article

Mitochondrial transfer RNA mutations and hypertension

Authors: S.L. Yin, C. Lan, H. Pei, and Z.Q. Zhu

Mutations in mitochondrial DNA have been found to be associated with hypertension. Of these, mitochondrial transfer RNA (mt-tRNA) is a hot spot for these pathogenic mutations. It is generally believed that these mutations may result in the failure of mt-tRNA metabolism, thereby worsening mitochondrial dysfunction and resulting in hypertension. mt-tRNA is .. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.42
DOI:
10.4238/2015.December.21.42
Human Genetics   Research Article

A new strategy for identification of currant (Ribes nigrum L.) cultivars using RAPD markers

Authors: J. Huo, G. Yang, Y. Zhang and F. Li

We developed a new approach using RAPD fingerprints to distinguish 37 currant cultivars from northeastern China based on optimization of RAPD by choosing 11 nucleotide primers and strict screening PCR annealing temperature. We found that the manual cultivar identification diagram (MCID) approach clearly developed fingerprints from 8 different primers that.. Read More»

Genet. Mol. Res. 12(2):
2013.June.21.1
DOI:
10.4238/2013.June.21.1
Medical Genetics   Research Article

A computational method to predict carbonylation sites in yeast proteins

Authors: H.Q. Lv,, J. Liu, J.Q. Han, J.G. Zheng and R.L. Liu

Several post-translational modifications (PTM) have been discussed in literature. Among a variety of oxidative stress-induced PTM, protein carbonylation is considered a biomarker of oxidative stress. Only certain proteins can be carbonylated because only four amino acid residues, namely lysine (K), arginine (R), threonine (T) .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028006
DOI:
10.4238/gmr.15028006
Plant Genetics   Research Article

Selection for wide adaptability and high phenotypic stability of Brazilian soybean genotypes

Authors: V.M. Oliveira, O.T. Hamawaki, A.O. Nogueira, L.B. Sousa, F.M. Santos and R.L. Hamawaki

Advances in genetic enhancement techniques have led to an increase in soybean production. Thus, soybean is currently one the most economically important cultured species worldwide. The objectives of the present study were to study the interaction of soybean genotypes per environment in terms of grain productivity and to evaluate their phenotypic adaptabil.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017843
DOI:
10.4238/gmr.15017843
Animal Genetics   Research Article

Genetic diversity of the honeybee Apis cerana in Yunnan, China, based on mitochondrial DNA

Authors: L. Yin and T. Ji

DNA sequence diversity in the tRNAleu-COII portion of the mitochondrial genome was investigated in samples of Apis cerana from Yunnan, China. A fragment of about 480 bp in tRNAleu-COII, including a noncoding area and part of COII, was sequenced. The noncoding area was 97-98 bp; 8 haplotypes were found, among which 5 had been reported previously, while 3 w.. Read More»

Genet. Mol. Res. 12(2):
2013.June.20.1
DOI:
10.4238/2013.June.20.1
Human Genetics   Research Article

Increased survivin expression and its association with clinical parameters of congenital choledochal cysts

Authors: Z.G. Wu, G.X. Li, B. Wang, Z.M. Chen and Q. Feng

The aim of the current study was to investigate survivin expression in congenital choledochal cysts (CCCs), and its associations with clinical parameters of CCCs. In total, 121 children with CCCs were included in this study as the case group, and their cysts were staged according to the Todani classification system. Additional.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028032
DOI:
10.4238/gmr.15028032