Electrophoresis and spectrometric analyses of adaptation-related proteins in thermally stressed Chromobacterium violaceum
Authors: I.B. Cordeiro1, D.P. Castro7, P.P.O. Nogueira7, P.C.S. Angelo6, P.A. Nogueira7, J.F.C. Gon?§alves8, A.M.R.F. Pereira9, J.S. Garcia2,3, G.H.M.F. Souza2,4, M.A.Z. Arruda5, M.N. Eberlin2, S. Astolfi-Filho1, E.V. Andrade1 and J.L. L?³pez-Lozano10
Chromobacterium violaceum is a Gram-negative proteobacteria found in water and soil; it is widely distributed in tropical and subtropical regions, such as the Amazon rainforest. We examined protein expression changes that occur in C. violaceum at different growth temperatures using electrophoresis and mass spectrometry. The total number of spots detected .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.1
- DOI:
- 10.4238/2013.October.29.1
Effects of cisplatin and panobinostat on human mesothelial (Met-5A) and malignant pleural mesothelioma (MSTO-211H) cells
Authors: K.E. Gultekin1, M.K. Yurdakonar1, E. Yaman1, U.S. Yuce1, A. Yilmaz2, E. Alp3, A. Celik4, S.M. Demiroz4 and H.I. Onen2
New therapeutic approaches are still needed for effective malignant pleural mesothelioma treatment. The use of classical chemotherapy agents in combination with newly developed molecules may shed light on new therapeutic approaches. We aimed to determine the efficacy of panobinostat, alone and in combination with cisplatin, on cell survival and mRNA expre.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.11.2
- DOI:
- 10.4238/2013.November.11.2
Cytotoxic effects of essential oils from three Lippia gracilis Schauer genotypes on HeLa, B16, and MCF-7 cells and normal human fibroblasts
Authors: J.O. Melo, A.L. Fachin, W.F. Rizo, H.C.R. Jesus, M.F. Arrigoni-Blank, P.B. Alves, M.A. Marins, S.C. Fran?§a and A.F. Blank
This study aimed to evaluate the chemical composition of the essential oils from three genotypes of Lippia gracilis Schauer (Verbenaceae) and investigate the cytotoxic activities of these oils. Essential oils were extracted from the leaves using a Clevenger-type apparatus, and chemical analysis was performed using a gas chroma.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.8.12
- DOI:
- 10.4238/2014.April.8.12
â??Extended Fitnessâ? hypothesis: a link between individual and group selection
Authors: S.J. de Souza
What are the targets of natural selection remains a controversial issue in Biology. Here I propose the “Extended Fitness” hypothesis, in which extended phenotypes emerge as a link between individual and group selection. The basic premise of the extended fitness hypothesis is that extended phenotypes can be used by members of the same group sin.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.17.5
- DOI:
- 10.4238/2013.October.17.5
Mapping of quantitative trait loci for the bolting trait in Brassica rapa under vernalizing conditions
Authors: Y.G. Wang, L. Zhang, X.H. Ji, J.F. Yan, Y.T. Liu, X.X. Lv and H. Feng
Premature bolting can occur occasionally during spring cultivation of heading Chinese cabbage in East Asia when the plants encounter low temperatures (vernalization), leading to economic loss. Breeding bolting-resistant cultivars is the best choice for solving this problem. We looked for QTLs responsible for varietal differenc.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.3
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.3
Effect of atorvastatin on vascular endothelial function in moderately nicotine-dependent smokers
Authors: X.Z. Cao, Z.R. Luo, H.M. Zhang and J.Q. Cai
We investigated the effect of atorvastatin on vascular endothelial function in moderately nicotine-dependent smokers. One hundred and sixty moderately nicotine-dependent smokers were randomly divided into the atorvastatin group (N = 80) and the control group (N = 80). Total cholesterol (TC), triglyceride, high-density lipoprot.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.8.13
- DOI:
- 10.4238/2014.April.8.13
Population variability of Bemisia tabaci (Genn.) in different hosts
Authors: G.E. do Valle, A.L. Louren?§?£o, M.I. Zucchi, J.B. Pinheiro and A.G. de Abreu
The silverleaf whitefly, Bemisia tabaci (Genn.) (Hemiptera: Aleyrodidae), is a cryptic species complex that contains some of the most damaging pests in tropical and subtropical regions. Recent studies have indicated that this complex is composed of at least 24 distinct and morphologically indistinguishable species that mainly differ in their ability to tr.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.17.4
- DOI:
- 10.4238/2013.October.17.4
Ginkgo biloba extract postconditioning reduces myocardial ischemia reperfusion injury
Authors: K. Ran, D.-L. Yang, Y.-T. Chang, K.-M. Duan, Y.-W. Ou, H.-P. Wang and Z.-J. Li
We examined the protective effects of Ginkgo biloba extract (EGb761) postconditioning on myocardial ischemia reperfusion injury in rabbits. Four groups of 8 white rabbits were allocated to: pseudo surgery group: the left coronary was lined without blocking for 160 min after thoracotomy; ischemia and reperfusion group (IR): the.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.8.14
- DOI:
- 10.4238/2014.April.8.14
Expression of RUNX3 gene in pancreatic adenocarcinoma and its clinical significance
Authors: L.-N. Xue, F.H. Bai2, X.-Y. Wang1, M. Lin1, Y. Tan1,2, X.-Y. Yao1 and K.-Q. Xu
We investigated the clinical significance of RUNX3 gene expression in human pancreatic carcinoma. Five samples of pancreatic tissues and 30 samples of pancreatic cancer tissues and paracancerous tissues were collected. RUNX3 expression was detected by real-time PCR and immunohistochemistry. The relationships between clinicopat.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.4
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.4
Reduced genetic diversity in endemic Brazilian Lymania spp (Bromeliaceae) populations and implications for conservation
Authors: V.C.C. Pampon?©t1, T.F. Alves2, R.A. Martinez3, R.X. Corr?ªa1,2 and F.A. Gaiotto1,2
We analyzed the genetic diversity of populations of two sympatric species of Lymania (Bromeliaceae), both endemic to the Atlantic rainforest of southern Bahia (Brazil). Lymania azurea has a restricted occurrence, while Lymania smithii has a wider distribution. Our aim was to provide genetic data to contribute to the design of more efficient conservation s.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.1
- DOI:
- 10.4238/2013.October.10.1