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Bioinformatics   Research Article

Variability analysis of �Persian� acid lime tree selections using agronomic and molecular markers

Authors: M.G. Santos, O.S. Passos, W.S. Soares Filho, E.A. Girardi, A.S. Gesteira and C.F. Ferreira

‘Persian’ acid lime (PAL) is the most important triploid commercial citrus crop planted in the world. Little is known about the genetic variability of the selections used in Brazil. Therefore, 25 genotypes originating from the PAL, and three control species, Citrus sunki, C. limon, and C. aurantiifolia, were assessed using inter-simple sequenc.. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.3
DOI:
10.4238/2013.October.17.3
Medical Genetics   Research Article

Analysis of protein-protein interaction network in chronic obstructive pulmonary disease

Authors: Y.P. Yuan, Y.H. Shi and W.C. Gu

Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality throughout the world. The purpose of our study was to uncover biomarkers and explore its pathogenic mechanisms at the molecular level. The gene expression profiles of COPD samples and normal controls were downloaded from Gene Expression Omnibus. Matlab was used for .. Read More»

Genet. Mol. Res. 13(4):
Plant Genetics   Research Article

Novel method to establish molecular identity using inter-simple sequence repeat markers in cotton (Gossypium hirsutum) cultivars

Authors: Z.-Y. Zhao, M.-X. Zhi, Z.-Y. Zhang, H.-L. Sun, Y.-S. Liu and X.-J. Li

Plant molecular identity (ID) is used to describe molecular characteristics of plants, which should contain all of the necessary information. Using inter-simple sequence repeat (ISSR) primers, molecular ID can be described in a way that reflects the polymerase chain reaction (PCR) conditions, annealing temperature, and the ban.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.23.5
DOI:
http://dx.doi.org/10.4238/2014.May.23.5
Plant Genetics   Research Article

Effects of glucose sensing/signaling on oxidative stress response in glucose repression mutants of Schizosaccharomyces pombe

Authors: B. Palabiyik, F. Jafari Ghods and E. Onay Ucar

The resistant to glucose repression mutants of Schizosaccharomyces pombe (ird5, ird13, and ird14) have a high tolerance to oxidative stress induced by H2O2. In all ird mutants, the increased expression level of the fbp1 gene can be interpreted as a lack of glucose repression in these mutants. To investigate the mechanisms of the oxidative stress response .. Read More»

Genet. Mol. Res. 12(4):
2013.October.25.3
DOI:
10.4238/2013.October.25.3
Medical Genetics   Research Article

Effects of metallothionein-3 and metallothionein-1E gene transfection on proliferation, cell cycle, and apoptosis of esophageal cancer cells

Authors: Z.Q. Tian, Y.Z. Xu, Y.F. Zhang, G.F. Ma, M. He and G.-Y. Wang

Metallothionein (MT)-3 has cell growth inhibitory activity, and is the only currently known MT subtype with unique physiological functions. The expression levels of MT-1E, a subtype of MT-1, were positively correlated with the degree of esophageal cancer malignancy. The present study aimed to investigate the effects of MT-3 and MT-1E gene transfection on .. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.2
DOI:
10.4238/2013.October.17.2
Animal Genetics   Research Article

Characterization and cross-species amplification of microsatellite markers in African Silverbill (Lonchura cantans)

Authors: N.R. Parine1, D. Kumar2, A.A.K. Pathan1, M.S. Elrobh1, W. Khan1,3 and M. Alanazi1

We tested the cross-amplification of eight microsatellites developed for Bengalese finch in African Silverbill (Lonchura cantans). In order to develop resources for conservation genetic studies in the species L. cantans, we tested the amplification success and polymorphism in eight previously developed microsatellite loci, in L. cantans. All eight microsa.. Read More»

Genet. Mol. Res. 12(4):
2013.November.18.12
DOI:
10.4238/2013.November.18.12
Microbial Genetics   Research Article

Analysis of cell cycle shortening and developmental interruption in Dictyostelium discoideum allC RNAi mutants

Authors: D.M. Xue, L.S. Hou, S.R. Zhang and N.X. Chen

Dictyostelium discoideum allC RNAi mutant cells are motile and aggregate together, but do not undergo further morphological development. The relatively quick growth rate of allC RNAi mutants compared to wild-type D. discoideum results in a shortened mutant cell cycle. However, at present, little is known about the mechanism un.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.23.6
DOI:
http://dx.doi.org/10.4238/2014.May.23.6
Animal Genetics   Research Article

Polymorphic microsatellite loci isolated from Cervus unicolor (Cervidae) show inbreeding in a domesticated population of Taiwan Sambar deer

Authors: D.Y. Lin, T.Y. Chiang, C.C. Huang, H.D. Lin, S.J. Tzeng, S.R. Kang, H.M. Sung and M.C. Wu

Primers for eight microsatellites were developed; they successfully amplified DNA from 20 domesticated Formosan Sambar deer (Cervus unicolor swinhoei). All loci were polymorphic, with 10-19 alleles per locus. The average observed heterozygosity across loci and samples was 0.310, ranging from 0 to 0.750 at each locus. All loci .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.23.7
DOI:
http://dx.doi.org/10.4238/2014.May.23.7
Human Genetics   Research Article

Association between primary open angle glaucoma and genetic polymorphisms GSTM1/GSTT1 in patients from Goi�¢nia Central-West Region of Brazil

Authors: C.T.X. Silva, N.B. Costa, K.S.F. Silva, R.E. Silva and K.K.V.O. Moura

In this study, we evaluated the genotype profile of GSTM1 and GSTT1 polymorphisms in patient carriers of primary open-angle glaucoma in the population of Goiânia, GO, Brazil. This case-control study included 100 Brazilian patients with glaucoma and 53 patients without glaucoma. Blood samples were genotyped for polymorphisms in GST genes using polyme.. Read More»

Genet. Mol. Res. 13(4):
Bioinformatics   Research Article

Genetic diversity of spineless Cereus jamacaru accessions using morphological and molecular markers

Authors: F.I.C. Oliveira, P.N. Bordallo, A.C.R. Castro and D. Correia

This is the first study to examine the genetic diversity of mandacaru cactus (Cereus jamacaru P. DC.). Plants of spineless mandacaru are commonly found in gardens and parks of urban areas in northeastern Brazil. In addition to exploring their ornamental potential, morphological, and genetic characterization may contribute to the development of plant mater.. Read More»

Genet. Mol. Res. 12(4):
2013.October.17.1
DOI:
10.4238/2013.October.17.1