Effect of glycerol on GHR and IGF-1 gene expression in breast muscle and on growth of Japanese meat quails
Authors: S.C.C. Silva, E. Gasparino, D.M. Voltolini, A.V. Pires, F. Tanamati, A.L.S. Garcia and D.P. de Oliveira
We evaluated messenger RNA (mRNA) expression of the growth-hormone (GHR) and insulin-like growth factor (IGF-1) genes in 28-day-old Japanese meat quails fed diets containing 0, 8, or 12% dietary glycerol in substitution of corn. Total RNA was extracted from the breast muscle and the DNA was amplified with specific primers using real-time PCR. Feed convers.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.3
- DOI:
- 10.4238/2013.September.23.3
Time-series microarray data simulation modeled with a case-control label
Authors: Y.J. Liu and J.Y. Zhang
With advances in molecular biology, microarray data have become an important resource in the exploration of complex human diseases. Although gene chip technology continues to grow, there are still many barriers to overcome, such as high costs, small sample sizes, complex procedures, poor repeatability, and the dependence on da.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027287
- DOI:
- 10.4238/gmr.15027287
Molecular cloning and gene expression analysis of cystatin C-like proteins in spinyhead croaker Collichthys lucidus
Authors: W. Song, K.J. Jiang, F.Y. Zhang, M. Zhao and L.B. Ma
Cystatins are natural tight-binding reversible inhibitors of cysteine proteases. In this study, a cDNA library was constructed from Collichthys lucidus using the SMART technique. A complete cDNA sequence with high identity to the conserved sequence of the cystatin C gene was cloned from the library using EST analysis and rapid.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017417
- DOI:
- 10.4238/gmr.15017417
Expression and clinical significance of Kelch-like epichlorohydrin-associated protein 1 in breast cancer
Authors: L. Zhang, W.P. Yang, L.Y. Wu, X. Zhu and C.Y. Wei
Our objective was to explore the expression and clinical significance of Kelch-like epichlorohydrin-associated protein 1 (Keap1) in breast cancer tissue. Eighty-one breast cancer patients having undergone surgical treatment in our hospital between March 2002 and December 2008 were enrolled in this study. Normal tissue adjacent.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027294
- DOI:
- 10.4238/gmr.15027294
Fine mapping and characterization of a novel dwarf and narrow-leaf mutant dnl1 in rice
Authors: X.J. Wei, S.Q. Tang, G.N. Shao, M.L. Chen, Y.C. Hu and P.S. Hu
Plant height is one of the most important agronomic traits of rice (Oryza sativa). Dwarf mutants are ideal materials for research on the mechanisms of regulation of rice plant height. We examined a new dwarf and narrow-leaf mutant dnl1. Phenotypic analysis showed that the dnl1 mutant has a thinner culm and more tillers, but the number of grains per panicl.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.2
- DOI:
- 10.4238/2013.September.23.2
A microRNA-152 that targets the phosphatase and tensin homolog to inhibit low oxygen induced-apoptosis in human brain microvascular endothelial cells
Authors: Y.H. Cao, D.G. Li, B. Xu1 M.Q. Wang, N. Zhen, L.X. Man,Y.Y. Zhang1 and M. Chi
Brain damage caused by perinatal asphyxia is dangerous for neonatal infants, but the mechanism by which it occurs remains elusive. In this study, microRNA-152 (miR-152) expression was induced by low oxygen levels in rat models of hypoxia brain damage, as well as in human brain microvascular endothelial cells (HBMECs) cultured .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027371
- DOI:
- 10.4238/gmr.15027371
Increased expression of the lncRNA BANCR and its prognostic significance in human osteosarcoma
Authors: Z.Q. Peng, R.B. Lu, D.M. Xiao and Z.M. Xiao
Long noncoding RNAs (lncRNAs) play important roles in the formation and progression of many types of human malignancies. The aim of our study was to investigate the expression and biological functions of the lncRNA BRAF-activated noncoding RNA (BANCR) in human osteosarcoma. BANCR expression was quantified by real-time PCR in h.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017480
- DOI:
- 10.4238/gmr.15017480
Expression of a GDP-L-galactose phosphorylase-like gene in a Chinese wild Vitis species induces responses to Erysiphe necator and defense signaling molecules
Authors: H.M. Hou, H.E. Li, M. Gao, H. Wang, C. Jiao and X.P. Wang
Using rapid amplification of cDNA ends, a full-length cDNA sequence of a GDP-L-galactose phosphorylase-like gene was isolated from leaves infected by Erysiphe necator in the Chinese wild (Vitis pseudoreticulata) clone, ‘Baihe-35-1’, an E. necator-resistant genotype. The full-length cDNA, designated as VpVTC, comprised 1943 bp and putatively en.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.1
- DOI:
- 10.4238/2013.September.23.1
Polymorphisms of rs1799983 (G>T) and rs1800780 (A>G) of the eNOS gene associated with susceptibility to essential hypertension in the Chinese Hui ethnic population
Authors: B. Yang, J.R. Xu, X.M. Liu, Y. Yang, X.F. Na, M. Li and Y.J. Wang
We investigated a possible association of polymorphism of the eNOS gene and essential hypertension in the Chinese Hui population; polymorphisms of rs2070744 (T>C), rs1799983 (G>T), rs1800780 (A>G), and rs3918181 (A>G) loci of the eNOS gene were examined. We found that the genotypic frequencies at rs1799983 and rs1800780 loci differed significa.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.26.2
- DOI:
- 10.4238/2013.March.26.2
Glucocorticoid receptor expression in the tonsils of children with obstructive sleep apnea hypopnea syndrome
Authors: X. Chen and J.R. Li
The expression of glucocorticoid receptor-α and -β (GR-α and GR-β) in the tonsil tissues of children with and without obstructive sleep apnea hypopnea syndrome (OSAHS) was evaluated. A total of 30 children with OSAHS who underwent tonsillectomy in the Navy General Hospital from June 2012 to June 2014 were.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017361
- DOI:
- 10.4238/gmr.15017361