Ectopic expression of Arabidopsis thaliana Na+(K+)/H+ antiporter gene, AtNHX5, enhances soybean salt tolerance
Authors: X.X. Wu, J. Li, X.D. Wu1, Q. Liu, Z.K. Wang, S.S. Liu, S.N. Li, Y.L. Ma, J. Sun, L. Zhao, H.Y. Li, D.M. Li, W.B. Li and A.Y. Su
Drought and salt stresses are the two major factors influencing the yield and quality of crops worldwide. Na+(K+)/H+ antiporters (NHXs) are ubiquitous membrane proteins that play important roles in maintaining the cellular pH and Na+(K+) homeostasis. The model plant Arabidopsis potentially encodes six NHX genes, namely AtNHX1 .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027483
- DOI:
- 10.4238/gmr.15027483
Relationship between the polymorphisms in KCNQ1 and type 2 diabetes in Chinese Kazakh population
Authors: L.J. Cui, X.Y. Chang, L.Y. Zhu, G. Feng, T. Zhou, C.X. Zhang, K.Y. Chong and K. Sun
Recently genome-wide association studies on East Asian populations reported an association between diabetes and several single nucleotide polymorphisms (SNPs) in a 40-kb linkage disequilibrium block in intron 15 of KCNQ1. However, the association between KCNQ1 variants and type 2 diabetes mellitus (T2DM) in Chinese Kazakh popu.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027503
- DOI:
- 10.4238/gmr.15027503
miRQuest: integration of tools on a Web server for microRNA research
Authors: R.R. Aguiar, L.A. Ambrosio, G. Sep�?ºlveda-Hermosilla, V. Maracaja-Coutinho and A.R. Paschoal
This report describes the miRQuest - a novel middleware available in a Web server that allows the end user to do the miRNA research in a user-friendly way. It is known that there are many prediction tools for microRNA (miRNA) identification that use different programming languages and methods to realize this task. It is diffic.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016861
- DOI:
- 10.4238/gmr.15016861
Effect of ozone on vascular endothelial growth factor (VEGF) and related inflammatory cytokines in rats with diabetic retinopathy
Authors: T.Y. Xie, W. Yan, J. Lou and X.Y. Chen
The aim of this study was to investigate the effect of ozone on inflammatory cytokines in diabetic retinopathy (DR) rats. Male rats (40) weighing 300-360 g were included in this study. Thirty rats were randomly divided into the model and ozone groups after DR was induced by streptozotocin. Ten rats served as the blank group. A.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027558
- DOI:
- 10.4238/gmr.15027558
Protective effect of the polarity of macrophages regulated by IL-37 on atherosclerosis
Authors: J. Huang, F.L. Hou, A.Y. Zhang and Z.L. Li
As an anti-inflammatory cytokine, interleukin-37 (IL-37) provides certain protective effects against inflammatory and autoimmune diseases. Recent reports indicate that IL-37 is expressed in foam cells of atherosclerotic plaques in both the coronary and carotid arteries of humans, suggesting the possible involvement of IL-37 in.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027616
- DOI:
- 10.4238/gmr.15027616
Development and characterization of Rift Valley fever virus-like particles
Authors: Y.T. Li, C.L. Wang, X.X. Zheng, H.L. Wang, Y.K. Zhao, W.W. Gai, H.L. Jin, Y.W. Gao, N. Li, S.T. Yang and X.Z. Xia
Rift Valley fever (RVF) is an acute, febrile zoonotic disease that is caused by the RVF virus (RVFV) and spread by arthropod vectors. RVF is currently prevalent in Africa and the Arabian Peninsula, and causes substantial economic losses. Furthermore, this disease poses a serious threat to animal and human health in regions wor.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017772
- DOI:
- 10.4238/gmr.15017772
Impact of cold ischemia on cytokines after partial liver transplantation in rats
Authors: Q.-A. Qi, Z.-Y. Yang, K.-S. Ma, Q. Lu, S.-G. Wang, X.-W. Li, F. Xia, W. Liu and P. Bie
To study the impact of cold ischemia on tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10) expression after liver transplantation, a stable model of partial liver transplantation in rats was established. The experimental animals were divided into the following groups: a partial hepatectomy control group, a group that received partial liv.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.1
- DOI:
- 10.4238/2013.September.27.1
De novo assembly and characterization of farmed blue fox (Alopex lagopus) global transcriptome using Illumina paired-end sequencing
Authors: P.C. Guo1*, S.Q. Yan1*, S. Si1, C.Y. Bai1, Y. Zhao1, Y. Zhang1, J.Y. Yao2 and Y.M. Li1
The blue fox (Alopex lagopus), a coat-color variant of the Arctic fox, is a domesticated fur-bearing mammal. In the present study, transcriptome data generated from a pool of nine different tissues were obtained with Illumina HiSeq2500 paired-end sequencing technology. After filtering from raw reads, 32,358,290 clean reads wer.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017603
- DOI:
- 10.4238/gmr.15017603
An A/G polymorphism rs3746444 in miR-499 is associated with increased cancer risk: a meta-analysis
Authors: N. Wang, ZQ Tian, Y. Li, R.M. Zhou and G.Y. Wang
An A/G polymorphism (rs3746444) has been identified in the miR-499 gene that can change the conformation of the secondary gene structure and thereby directly affect binding to target mRNAs and the microRNA (miRNA) maturation process, thus altering protein expression and potentially contributing to cancer susceptibility. Numerous studies investigating the .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.14
- DOI:
- 10.4238/2013.September.23.14
Molecular evolution and adaptation of the mitochondrial cytochrome b gene in the subgenus Martes
Authors: B. Li, B. Malyarchuk, X.B. He and M. Derenko
Martes species represent a typical example of rapid evolutionary radiation and a recent speciation event. To identify regions of the genome that experienced adaptive evolution, which might provide clues to their functional importance and may be informative about the features that make each species unique, we sought evidence of molecular adaptation in the .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.13
- DOI:
- 10.4238/2013.September.23.13