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Human Genetics   Research Article

Isolation, identification, and degradation performance of a PFOA-degrading strain

Authors: L.B. Yi, L.Y. Chai, Y. Xie, Q.J. Peng and Q.Z. Peng

The perfluorooctanoic acid (PFOA)-degrading strain YAB1 was isolated from the soil near a perfluorinated compound production plant through acclimation and enrichment culture, using PFOA as the sole carbon source. This strain was preliminarily identified as Pseudomonas parafulva based on colony morphology, physiological and bio.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028043
DOI:
10.4238/gmr.15028043
Human Genetics   Research Article

Evolution of mustard (Brassica juncea Coss) subspecies in China: evidence from the chalcone synthase gene

Authors: F.B. Chen, H.F. Liu, Q.L. Yao and P. Fang

To explore the phylogenetic relationship, genome donor, and evolutionary history of the polyploid mustard (Brassica juncea) from China, eighty-one sequences of the chalcone synthase gene (Chs) were analyzed in 43 individuals, including 34 B. juncea, 2 B. rapa, 1 B. nigra, 2 B. oleracea, 1 B. napus, 1 B. carinata, and 2 Raphanu.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028045
DOI:
10.4238/gmr.15028045
Plant Genetics   Research Article

Genetic diversity and relationship of chicory (Cichorium intybus L.) using sequence-related amplified polymorphism markers

Authors: X.Y. Liang, X.Q. Zhang, S.Q. Bai, L.K. Huang, X.M. Luo, Y. Ji and L.F. Jiang

Chicory is a crop with economically important roles and is cultivated worldwide. The genetic diversity and relationship of 80 accessions of chicories and endives were evaluated by sequence-related amplified polymorphism (SRAP) markers to provide a theoretical basis for future breeding programs in China. The polymorphic rate wa.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.11
DOI:
10.4238/2014.September.26.11
Human Genetics   Research Article

Network spatio-temporal analysis predicts disease stage-related genes and pathways in renal cell carcinoma

Authors: X.H. Li, C.Z. Yang and J. Wang

The purpose of this study was to screen the key genes and pathways of renal cell carcinoma (RCC) and lay the foundation for its diagnosis and therapy. Microarray data of normal subjects and RCC patients at different stages of disease were used to screen differentially expressed genes (DEGs). Based on the DEGs in the four disea.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028061
DOI:
10.4238/gmr.15028061
Animal Genetics   Research Article

Effects of acrylonitrile on lymphocyte lipid rafts and RAS/RAF/MAPK/ERK signaling pathways

Authors: X.J. Li, B. Li, J.S. Huang, J.M. Shi, P. Wang, W. Fan and Y.L. Zhou

Acrylonitrile (ACN) is a widely used chemical in the production of plastics, resins, nitriles, acrylic fibers, and synthetic rubber. Previous epidemiological investigations and animal studies have confirmed that ACN affects the lymphocytes and spleen. However, the immune toxicity mechanism is unknown. Lipid rafts are cell memb.. Read More»

Genet. Mol. Res. 13(3):
2014.September.26.12
DOI:
10.4238/2014.September.26.12
Plant Genetics   Research Article

Screening and characterization of novel polymorphic microsatellite markers from sea cucumber Holothuria leucospilota

Authors: J.B. Shangguan, Z.B. Li, Y.F. Ning, Y.S. Huang, Y. Yuan, J. Lu, B.B. Li and X.Q. Mao

The sea cucumber Holothuria leucospilota has high medicinal value and rich nutritional edible value, and thus is a commercially important aquatic product in China. Microsatellite loci were developed and screened using a fast isolation protocol and amplified fragment length polymorphism of sequences containing repeats. In this study, 16 novel polymorphic m.. Read More»

Genet. Mol. Res. 14(2):
2015.June.12.9
DOI:
10.4238/2015.June.12.9
Human Genetics   Research Article

Expression of transforming growth factor-�²1 in neonatal rats with hyperoxia-induced bronchopulmonary dysplasia and its relationship with lung development

Authors: B. Yan, W. Zhong, Q.M. He, S.Y. Zhang, J.K. Yu and Y.L. Pan

The aim of this study was to detect the expression of transforming growth factor-ß1 (TGF-ß1) in neonatal rats with hyperoxia-induced bronchopulmonary dysplasia (BPD) and to explore its relationship with lung development. Forty-eight rats (2-3 days old) were randomly divided into a hyperoxia group and a control grou.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028064
DOI:
10.4238/gmr.15028064
Plant Genetics   Research Article

Phenotypic and biochemical profile changes in calendula (Calendula officinalis L.) plants treated with two chemical mutagenesis

Authors: Y.I. El-Nashar and A.A. Asrar

Chemical mutagenesis is an efficient tool used in mutation-breeding programs to improve the vital characters of the floricultural crops. This study aimed to estimate the effects of different concentrations of two chemical mutagens; sodium azide (SA) and diethyl sulfate (DES). The vegetative growth and flowering characteristics.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028071
DOI:
10.4238/gmr.15028071
Human Genetics   Research Article

Comparison of the expression of human equilibrative nucleotide transporter 1 (hENT1) and ribonucleotide reductase subunit M1 (RRM1) genes in seven non-Hodgkin lymphoma cell lines

Authors: H.B. Zhao, X.F. Zhang, F. Shi, M.Z. Zhang and W.L. Xue

We investigated the variability in the expression of human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase subunit M1 (RRM1) in non-Hodgkin lymphoma cell lines. hENT1 and RRM1 mRNA expression levels in natural killer (NK) cells and seven non-Hodgkin lymphoma cell lines (YTS, SNK-6, Jeko-1, ly-1, Raj.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028275
DOI:
10.4238/gmr.15028275
Human Genetics   Research Article

Apelin polymorphism predicts blood pressure response to losartan in older Chinese women with essential hypertension

Authors: J. Jia, C. Men, K.-T. Tang and Y.-Y. Zhan

We determined whether the blood pressure response to losartan in an older Chinese population with essential hypertension was associated with apelin gene polymorphisms. We genotyped the -1860T>C polymorphism of the apelin gene in a case-control study of 222 patients with hypertension and 250 controls. Following 24 weeks of treatment with losartan (50 mg.. Read More»

Genet. Mol. Res. 14(2):
2015.June.12.10
DOI:
10.4238/2015.June.12.10