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Plant Genetics   Research Article

Analysis of sequence diversity through internal transcribed spacers and simple sequence repeats to identify Dendrobium species

Authors: Y.T. Liu, R.K. Chen, S.J. Lin, Y.C. Chen, S.W. Chin, F.C. Chen and C.Y. Lee

The Orchidaceae is one of the largest and most diverse families of flowering plants. The Dendrobium genus has high economic potential as ornamental plants and for medicinal purposes. In addition, the species of this genus are able to produce large crops. However, many Dendrobium varieties are very similar in outward appearance.. Read More»

Genet. Mol. Res. 13(2):
2014.April.8.15
DOI:
10.4238/2014.April.8.15
Medical Genetics   Research Article

High-sensitivity cardiac troponin T is a predictor of recurrent acute coronary syndrome in patients with acute myocardial infarction

Authors: S.-C. Sheng, X.-M. Lu, Y. Kang, Y.-P. Du and G.-X. Wang

High-sensitivity cardiac troponin T is a useful tool for diagnosing myocardial ischemia. However, its role in the prognosis of patients with acute myocardial infarction has not been studied. Here, the prognostic value of high-sensitivity cardiac troponin T for patients with acute myocardial infarction was investigated. The con.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.6
DOI:
http://dx.doi.org/10.4238/2014.May.16.6
Medical Genetics   Research Article

Association of -238G/A and -863C/A polymorphisms in the TNF-�± gene with chronic obstructive pulmonary disease based on a meta-analysis

Authors: K. Cui, X.Y. Ge and H.L. Ma

Chronic obstructive pulmonary disease (COPD) is a chronic systemic inflammatory disease; increasing evidence indicates that the TNF-α polymorphism is associated with progression of this disease. Few studies have focused upon association between TNF-α -238G/A or -863C/A polymorphism and COPD risk. Reported associations have been controversial b.. Read More»

Genet. Mol. Res. 12(4):
2013.October.24.10
DOI:
10.4238/2013.October.24.10
Animal Genetics   Research Article

Transient increase in IL-1�², IL-6 and TNF-�± gene expression in rat liver exposed to gold nanoparticles

Authors: H.A. Khan, M.A.K. Abdelhalim, A.S. Alhomida, M.S. Al Ayed

Most studies have used in vitro systems to test inflammatory responses of nanoparticles; these may not reflect the real biological response of body organs. In fact, certain nanoparticles have provoked opposite effects under in vitro and in vivo conditions. Current understanding of the biocompatibility of gold nanoparticles is .. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.12
DOI:
10.4238/2013.November.22.12
Plant Genetics   Research Article

Genetic diversity of the Chinese traditional herb Blumea balsamifera (Asteraceae) based on AFLP markers

Authors: Y.X. Pang, W.Q. Wang, Y.B. Zhang, Y. Yuan, J.B. Yu, M. Zhu and Y.Y. Chen

Blumea balsamifera is a commercially important medicinal herb in China and other parts of Asia. It is used to produce borneol. This plant grows in the wild, but resources have diminished greatly in recent years. We examined the genetic diversity of this species to help develop conservation strategies; 35 plants from five provi.. Read More»

Genet. Mol. Res. 13(2):
2014.April.14.1
DOI:
10.4238/2014.April.14.1
Cytogenomics   Research Article

Genetic contribution of CYP2C9, CYP2C19, and APOE variants in acenocoumarol response

Authors: J.A. Nastasi-Catanese1, J.R. Padilla-Guti�©rrez2, Y. Valle2, F. Ortega-Guti�©rrez3, M.P. Gallegos-Arreola4 and L.E. Figuera5,6

Oral anticoagulants of the coumarin type have an inconveniently narrow therapeutic window, making their use difficult. In Mexico, genetic variables that participate in the heterogeneity of the therapeutic response remain poorly investigated. With the focus on warfarin, extensive pharmacogenomic studies have been performed, including those on the CYP450 fa.. Read More»

Genet. Mol. Res. 12(4):
2013.October.10.7
DOI:
10.4238/2013.October.10.7
Medical Genetics   Research Article

Association of polymorphisms of the xeroderma pigmentosum complementation group F gene with increased glioma risk

Authors: W.K. Zhou, L.Y. Huang, L. Hui, Z.W. Wang, B.Z. Jin, X.L. Zhao, X.Z. Zhang, J.X. Wang, J.C. Wang and R.Z. Wang

We aimed to investigate the role of 4 single nucleotide polymorphisms of the xeroderma pigmentosum complementation group F (XPF) gene (rs3136038, rs1799798, rs1800067, and rs2276466) in glioma, and the roles of gene-gene interactions in the risk of developing this type of cancer. We collected samples from 225 glioma cases and .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.7
DOI:
http://dx.doi.org/10.4238/2014.May.16.7
Medical Genetics   Research Article

Keloid microRNA expression analysis and the influence of miR-199a-5p on the proliferation of keloid fibroblasts

Authors: Z.-Y. Wu, L. Lu, J. Liang, X.-R. Guo, P.H. Zhang and S.-J. Luo

The purpose of this study was to identify microRNAs (miRNAs) involved in keloid formation and determine their influence on the proliferation of keloid fibroblasts (KFs). Eight specimens each of resected keloid tissue and normal skin tissue were collected. miRNAs that are differentially expressed in keloid tissue and normal ski.. Read More»

Genet. Mol. Res. 13(2):
2014.April.14.2
DOI:
10.4238/2014.April.14.2
Medical Genetics   Research Article

Expression of multidrug resistance 1 and multidrug resistance-related protein 1 in C57BL/6 mice treated with benzene

Authors: J.-S. Huang, M.-D. Zhao, J.-M. Shi, J.-H. Zhang, B. Li, W. Fan, Y.-L. Zhou

ATP-binding cassette super family (ABC) proteins are considered key to oncology and pharmacology studies. We examined the effect of benzene on ABC pump protein levels in C57BL/6 mouse bone marrow mononuclear cells. After a 2-week gavage (200 mg/kg, 5 days per week), the number of peripheral leukocytes, lymphocytes and basophil.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.11
DOI:
10.4238/2013.November.22.11
Human Genetics   Research Article

Complete mitochondrial genome sequence of Marmota himalayana (Rodentia: Sciuridae) and phylogenetic analysis within Rodentia

Authors: Q.J. Chao, Y.D. Li, X.X. Geng, L. Zhang, X. Dai, X. Zhang, J. Li and H.J. Zhang

This is the first report of a complete mitochondrial genome sequence from Himalayan marmot (Marmota himalayana, class Marmota). We determined the M. himalayana mitochondrial (mt) genome sequence by using long-PCR methods and a primer-walking sequencing strategy with genus-specific primers. The complete mt genome of M. himalaya.. Read More»

Genet. Mol. Res. 13(2):
2014.April.14.3
DOI:
10.4238/2014.April.14.3