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Medical Genetics   Research Article

Homocysteine induces blood vessel global hypomethylation mediated by LOX-1

Authors: X.L. Yang, J. Tian, Y. Liang, C.J. Ma, A.N. Yang, J. Wang, S.C. Ma, Y. Cheng, X. Hua and Y.D. Jiang

Homocysteine (Hcy) is an independent risk factor of atherosclerosis through its involvement with the methionine cycle. In this study, we aimed to determine the blood vessel global methylation rate in Hcy-induced atherosclerosis in apolipoprotein-E-deficient (ApoE-/-) mice, and to explore the possible mechanism of this change i.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.2
DOI:
http://dx.doi.org/10.4238/2014.May.16.2
Animal Genetics   Research Article

Isolation and characterization of polymorphic microsatellite loci in the swimming crab Portunus trituberculatus (Portunidae) L.P.

Authors: L.P. Ren, Y. Qin, X.C. Li, Y.N. Sun, R.X. Wang

The Swimming crab Portunus trituberculatus (Portunidae) is an important economically food species. To provide molecular markers for P. trituberculatus, we isolated and characterized polymorphic microsatellite markers. We developed a 5'-anchored genomic library of P. trituberculatus DNA, and derived 45 positive clones. We desig.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.19
DOI:
10.4238/2013.November.22.19
Plant Genetics   Research Article

Genome-wide identification and phylogenetic analysis of the SBP-box gene family in melons

Authors: Y. Ma, J.W. Guo, R. Bade, Z.H. Men and A. Hasi

The SBP-box gene family is specific to plants and encodes a class of zinc finger-containing transcription factors with a broad range of functions. Although SBP-box genes have been identified in numerous plants, including green algae, moss, silver birch, snapdragon, Arabidopsis, rice, and maize, there is little information concerning SBP-box genes, or the .. Read More»

Genet. Mol. Res. 13(4):
Animal Genetics   Research Article

Inter-retrotransposon-amplified polymorphism markers for germplasm characterization in Manihot esculenta (Euphorbiaceae)

Authors: A.M. Oliveira-Silva, G.F. Silva, M.C. Dias, C.R. Clement and N.R. Sousa

Manioc, Manihot esculenta, is economically important in many tropical and subtropical countries. The genetic variability of the species has not been fully explored, and new information may help expand its use. Molecular markers based on retrotransposons have good potential for analysis of genetic diversity given their abundanc.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.3
DOI:
http://dx.doi.org/10.4238/2014.May.16.3
Plant Genetics   Research Article

Development and characterization of novel expressed sequence tag-derived simple sequence repeat markers in Hevea brasiliensis (rubber tree)

Authors: Z.W. An, Y.C. Li, Q.L. Zhai, L.L. Xie, Y.H. Zhao, H.S. Huang

Cultivated clones of Hevea brasiliensis have a narrow genetic base. In order to broaden the genetic base, it is first necessary to investigate the genetic diversity of wild populations. Expressed sequence tag-simple sequence repeat (EST-SSR) markers were developed to investigate the genetic diversity of Hevea populations. Four.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.18
DOI:
10.4238/2013.November.22.18
Microbial Genetics   Research Article

Complete mitochondrial genomes of the Bright Sunbeam Curetis bulis and the Small Copper Lycaena phlaeas (Lepidoptera: Lycaenidae) and their phylogenetic implications

Authors: L.L. Zhang1, J.S. Hao1,2, D.Y. Huang1, X.Y. Sun2, J.J. Hao1, C.M. Peng1 and Q. Yang2

In this study, the complete mitochondrial genomes of Curetis bulis and Lycaena phlaeas were determined and analyzed. The circular genomes are 15,162 bp long for C. bulis and 15,280 bp long for L. phlaeas, with a total A+T content of 82.6 and 83.1%, respectively. Both mitogenomes contain 37 genes, and their gene orders are similar to those of other lepidop.. Read More»

Genet. Mol. Res. 12(4):
2013.October.10.9
DOI:
10.4238/2013.October.10.9
Plant Genetics   Research Article

Evaluation of castor bean genotypes sown in winter and summer at a low altitude

Authors: G.E.M. Lopes, H.D. Vieira and F.L. Partelli

Current demands for the genetic breeding of castor bean include the adaptation of genotypes to low altitudes to expand the potential areas of cultivation. This study was conducted to evaluate the response of different genotypes of castor bean that were sown in winter and summer at a low altitude. The study was conducted in northwestern Rio de Janeiro Stat.. Read More»

Genet. Mol. Res. 13(4):
Animal Genetics   Research Article

Influence of animals obtained using embryo transfer on the genetic evaluation of growth in Simmental beef cattle with random regression models

Authors: R.R. Mota, P.S. Lopes, L.F.A. Marques, L.P. Silva,M. Concei�§�£o Pessoa, R. Almeida Torres, M.D.V. Resende

Weight records of Simmental beef cattle were used in a genetic evaluation of growth with and without embryo transfer (ET). A random regression model in which ET individuals were excluded (RRM1) contained 29,510 records from 10,659 animals, while another model that did not exclude these animals (RRM2) contained 62,895 records f.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.17
DOI:
10.4238/2013.November.22.17
Plant Genetics   Research Article

Characterization of Anatolian traditional quince cultivars, based on microsatellite markers

Authors: C. Y�¼ksel, F. Mutaf, �°. Demirta��, G. ��zt�¼rk, M. Pekta��, A. Erg�¼l

We conducted simple sequence repeat (SSR) analyses of 15 traditional quince (Cydonia oblonga) cultivars from Anatolian gene sources for molecular characterization and investigation of genetic relationships. Three pear and two apple cultivars were used as references for SSR locus data analysis and to determine allele profiles b.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.16
DOI:
10.4238/2013.November.22.16
Human Genetics   Research Article

Syndromic and non-syndromic forms of retinitis pigmentosa: a comprehensive Italian clinical and molecular study reveals new mutations

Authors: C.O. Pierrottet, M. Zuntini, M. Digiuni, I. Bazzanella, P. Ferri, R. Paderni, L.M. Rossetti, S. Cecchin, N. Orzalesi and M. Bertelli

Mutations in more than 60 different genes have been associated with non-syndromic and syndromic retinitis pigmentosa (RP), a heterogeneous group of inherited retinal dystrophies. To increase the understanding of the molecular epidemiology of the disease in Italy, we analyzed 56 patients with syndromic and non-syndromic forms of RP attending the Retinitis .. Read More»

Genet. Mol. Res. 13(4):