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Microbial Genetics   Research Article

Genome-wide identification and expression profiling of the fatty acid desaturase gene family in the silkworm, Bombyx mori

Authors: Q.M. Chen, D.J. Cheng, S.P. Liu, Z.G. Ma, X. Tan and P. Zhao

Fatty acid desaturases exist in all living organisms and play important roles in many different biologic processes, such as fatty acid metabolism, lipid biosynthetic processes, and pheromone biosynthetic processes. Using the available silkworm genome sequence, we identified 14 candidate fatty acid desaturase genes. Eleven gene.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.13.2
DOI:
http://dx.doi.org/10.4238/2014.May.13.2
Animal Genetics   Research Article

Genetic variations in the leptin gene associated with growth and carcass traits in Nellore cattle

Authors: D.B.S. Silva, B.A. Crispim, L.E. Silva, J.A. Oliveira, F. Siqueira, L.O. Seno and A.B. Grisolia

The aim of the study was to detect polymorphisms in the leptin gene and to determine the association of these polymorphisms with growth and carcass traits in Nellore cattle. The single nucleotide polymorphisms (SNPs) -1457 (AJ571671:g.-1457A>G) and A59V (AF536174.1:g. 321C>T), as well as the microsatellite BM1500 (3.9 kb.. Read More»

Genet. Mol. Res. 13(2):
2014.April.16.9
DOI:
10.4238/2014.April.16.9
Animal Genetics   Research Article

Comparative study between Ephedra sinica Stapf and Fructus Schisandrae Chinensis on ET-1 and 6-keto-prostaglandin F1�± in rats with idiopathic pulmonary fibrosis

Authors: H.Q. Zhai, J.R. Hhang, M.C. Gao, Y. Liu, S.F. Zhang, X.H. Wang, F.Y. Meng and Y.P. Wang

The aim of this study was to evaluate differences in the effects of Ephedra sinica Stapf and Fructus Schisandrae Chinensis on angiogenesis in the treatment of bleomycin-induced rat idiopathic pulmonary fibrosis. The rat models were created using bleomycin. The animals were divided into six groups: model, control, Ephedra alone.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.13.3
DOI:
http://dx.doi.org/10.4238/2014.May.13.3
Human Genetics   Research Article

Development and characterization of novel transcriptome-derived microsatellites for genetic analysis of persimmon

Authors: C. Luo, Q.L. Zhang and Z.R. Luo

Oriental persimmon (Diospyros kaki Thunb.) (2n = 6x = 90) is a major commercial and deciduous fruit tree that is believed to have originated in China. However, rare transcriptomic and genomic information on persimmon is available. Using Roche 454 sequencing technology, the transcriptome from RNA of the flowers of D. kaki was a.. Read More»

Genet. Mol. Res. 13(2):
2014.April.16.10
DOI:
10.4238/2014.April.16.10
Plant Genetics   Research Article

Diversity resistance to Puccinia striiformis f. sp Tritici in rye chromosome arm 1RS expressed in wheat

Authors: M.Y. Yang, T.H. Ren, B.J. Yan, Z. Li and Z.L. Ren

The 1BL.1RS wheat-rye translocation contained in the Russian cultivar Aurora has been the most widespread alien translocation in wheat-breeding programs all over the world. However, following the prevalence of new biotypes of the pathogens, disease-resistance genes in this translocation chromosome have been overcome and consequently they have been elimina.. Read More»

Genet. Mol. Res. 13(4):
Plant Genetics   Research Article

Roles of the bZIP gene family in rice

Authors: Z.G. E, Y.P. Zhang, J.H. Zhou and L. Wang

The basic leucine zipper (bZIP) genes encode transcription factors involved in the regulation of various biological processes. Similar to WRKY, basic helix-loop-helix, and several other groups of proteins, the bZIP proteins form a superfamily of transcription factors that mediate plant stress responses. In this review, we pres.. Read More»

Genet. Mol. Res. 13(2):
2014.April.16.11
DOI:
10.4238/2014.April.16.11
Human Genetics   Research Article

Genetic diversity of Saccharum spontaneum from geographical regions of China assessed by simple sequence repeats

Authors: L.N. Fan, H.H. Deng, Q.W. Luo, H.Y. He, Y. Li, Q.N. Wang, Z.X. Huang, J.T. Wu, Q.W. Li, S.M. Liu and Y.W. Qi

Saccharum spontaneum is the most variable wild relative of sugarcane with potential for use in sugarcane improvement programs. In order to help preserve and exploit this species, 152 accessions from eight major geographical regions in China, including Hainan, Guangdong, Guangxi, Yunnan, Sichuan, Guizhou, Fujian, and Jiangxi pr.. Read More»

Genet. Mol. Res. 12(4):
2013.November.26.1
DOI:
10.4238/2013.November.26.1
Medical Genetics   Research Article

Polymorphisms in the XRCC1 gene are associated with treatment response to platinum chemotherapy in advanced non-small cell lung cancer patients based on meta-analysis

Authors: L. Li, C. Wan and F.Q. Wen

X-ray repair cross complementing group 1(XRCC1) polymorphisms have been implicated in interindividual variability of efficacy of platinum chemotherapy for treating non-small cell lung cancer (NSCLC); however, results of different studies have been inconsistent. We conducted a meta-analysis to investigate the association betwee.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.1
DOI:
http://dx.doi.org/10.4238/2014.May.16.1
Medical Genetics   Research Article

Homocysteine induces blood vessel global hypomethylation mediated by LOX-1

Authors: X.L. Yang, J. Tian, Y. Liang, C.J. Ma, A.N. Yang, J. Wang, S.C. Ma, Y. Cheng, X. Hua and Y.D. Jiang

Homocysteine (Hcy) is an independent risk factor of atherosclerosis through its involvement with the methionine cycle. In this study, we aimed to determine the blood vessel global methylation rate in Hcy-induced atherosclerosis in apolipoprotein-E-deficient (ApoE-/-) mice, and to explore the possible mechanism of this change i.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.2
DOI:
http://dx.doi.org/10.4238/2014.May.16.2
Animal Genetics   Research Article

Isolation and characterization of polymorphic microsatellite loci in the swimming crab Portunus trituberculatus (Portunidae) L.P.

Authors: L.P. Ren, Y. Qin, X.C. Li, Y.N. Sun, R.X. Wang

The Swimming crab Portunus trituberculatus (Portunidae) is an important economically food species. To provide molecular markers for P. trituberculatus, we isolated and characterized polymorphic microsatellite markers. We developed a 5'-anchored genomic library of P. trituberculatus DNA, and derived 45 positive clones. We desig.. Read More»

Genet. Mol. Res. 12(4):
2013.November.22.19
DOI:
10.4238/2013.November.22.19