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Animal Genetics   Research Article

Identification of COL6A1 as a differentially expressed gene in human astrocytomas

Authors: A. Fujita, J.R. Sato, F. Festa, L.R. Gomes, S.M. Oba-Shinjo,S.K.N. Marie, C.E. Ferreira and M.C. Sogayar

Diffuse infiltrating gliomas are the most common tumors of the central nervous system. Gliomas are classified by the WHO according to their histopathological and clinical characteristics into four classes: grade I (pilocytic astrocytoma), grade II (diffuse astrocytoma), grade III (anaplastic astrocytoma), and grade IV (gliobla.. Read More»

Genet. Mol. Res. 7(2):
vol7-2gmr432
DOI:
10.4238/vol7-2gmr432
Microbial Genetics   Research Article

Polymorphic microsatellite loci in the rapid racerunner Eremias velox (Squamata: Lacertidae)

Authors: H. Li, Z.-S. Zhou, J. Guo and L.H. Lin

We isolated and characterizated 12 polymorphic microsatellite loci in the rapid racerunner Eremias velox (Squamata: Lacertidae). The loci were screened in 37 E. velox individuals. The number of alleles ranged from 6 to 16. The observed heterozygosity ranged from 0.432 to 0.919, and the expected heterozygosity ranged from 0.685 to 0.902. These microsatelli.. Read More»

Genet. Mol. Res. 11(4):
2012.October.9.5
DOI:
10.4238/2012.October.9.5
Medical Genetics   Research Article

Population genetic structure and its implication in the conservation of Schizopygopsis pylzovi in Yellow River as inferred from mitochondrial DNA sequence analysis

Authors: 11

To assess the genetic diversity, structure, and population dynamics of Schizopygopsis pylzovi, we examined the changes in mitochondrial DNA sequences (the mtDNA control region and the Cyt b gene; 1835 bp) in 304 individuals from nine populations. The samples were segregated into 112 haplotypes, with high haplotype diversity an.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038480
DOI:
10.4238/gmr.15038480
Plant Genetics   Research Article

Genetic diversity of Metrodorea nigra (Rutaceae) from a small forest remnant in Brazil assessed with microsatellite markers

Authors: M.C. Guidugli, R. Ferreira-Ramos, A.C.B. de Sousa, F.W. Cidade, T.G. Marconi, M.A. Mestriner, M. Groppo and A.L. Alzate-Marin

Metrodorea nigra (Rutaceae) is an endemic Brazilian tree of great ecological importance, frequently found in the submontane regions of ombrophilous dense and semideciduous forests. This tree is useful for reforesting degraded areas and the wood can be employed in construction. We developed 12 microsatellite markers from a geno.. Read More»

Genet. Mol. Res. 11(1):
http://dx.doi.org/2012.January.9.2
DOI:
http://dx.doi.org/10.4238/2012.January.9.2
Animal Genetics   Research Article

Cytogenetic studies in Brazilian marine Sciaenidae and Sparidae fishes (Perciformes)

Authors: I.V. Accioly and W.F. Molina

Fishes from the families Sciaenidae and Sparidae, the former comprising coastal species associated with shallow waters on the continental shelf and the latter composed of typically marine species, are of significant economic value. Karyotypic data are available for about 20% of the total number of species in these groups. In t.. Read More»

Genet. Mol. Res. 7(2):
vol7-2gmr427
DOI:
10.4238/vol7-2gmr427
Microbial Genetics   Research Article

Molecular characterization and upregulation of cytosolic manganese superoxide dismutase by imidazole derivative KK-42 in Macrobrachium nipponense

Authors: W.F. Wang, L.M. Mu, X.S. Wu, H. Yang and Q.J. Ning

Imidazole derivative KK-42 is a well-known regulator of insect growth. KK-42 pretreatment has been shown to promote the survival of Macrobrachium nipponense infected with Aeromonas hydrophila, possibly via activation of superoxide dismutase (SOD). In this study, the cytMnSOD gene was cloned from the hepatopancreas of M. nippon.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038484
DOI:
10.4238/gmr.15038484
Human Genetics   Research Article

Human papillomavirus viral load in cervical intraepithelial neoplasia as a prognostic factor in a Mexican population

Authors: A.E. Bencomo-?lvarez, I. Limones-Perches, A.E. Su?¡rez-Rinc?³n, L.J. Ram?­rez-Jirano, E. Borrayo-Carbajal, J. S?¡nchez-Corona and H. Montoya-Fuentes

Persistent infection with human papillomavirus (HPV) has been recognized as the main etiological factor of morbimortality in cervical cancer. Several factors have been associated with the development of cervical disease, but viral load has recently been proposed as an indicator of cervical neoplasia. Therefore, a single measur.. Read More»

Genet. Mol. Res. 11(4):
2012.October.4.2
DOI:
10.4238/2012.October.4.2
Medical Genetics   Research Article

Characterization and evolution of the mitochondrial DNA control region in Ranidae and their phylogenetic relationship

Authors: Z.H. Huang and F.Y. Tu

The control region is considered to be one of the most variable parts of animal mitochondrial DNA (mtDNA). We compared the mtDNA control region from 37 species representing 14 genera and 4 subfamilies of Ranidae, to analyze the evolution of the control region and to determine their phylogenetic relationship. All the Ranidae sp.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038491
DOI:
10.4238/gmr.15038491
Human Genetics   Case Reports

Overwhelming postsplenectomy infection

Authors: C.-F. Sheng, B.-Y. Liu, H.-M. Zhang and X. Zheng

This report aims to deepen the understanding of the pathogenesis, diagnosis, clinical characteristics, and treatment of overwhelming postsplenectomy infection (OPSI). A patient treated at Taihe Hospital for tuberculous OPSI is described, and relevant literature is reviewed. Broad-spectrum antibiotics, suppression of the systemic inflammatory reaction, and.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.30
DOI:
http://dx.doi.org/10.4238/2015.March.30.30
Human Genetics   Research Article

Combined analysis of the MspI and XbaI polymorphisms in intron 22 of the factor VIII gene for detection of hemophilia A in a Korean population.

Authors: S.H. Park, N. Chung, M.R. Lee, S.K. Yoo and Y.M. Choi

To determine the usefulness of MspI/int22h-1 (intron 22 homologous region-1) polymorphism of the factor VIII gene for molecular genetic diagnosis of hemophilia A in the Korean population, MspI/intron 22 and XbaI/intron 22 polymorphisms were analyzed in 101 unrelated Korean families with severe hemophilia A. The expected hetero.. Read More»

Genet. Mol. Res. 11(1):
http://dx.doi.org/2012.January.9.1
DOI:
http://dx.doi.org/10.4238/2012.January.9.1