IL-8 mRNA expression in the mouse mammary glands during pregnancy and lactation
Authors: H.P. Li, Y.J. Guo, H.S. Zhu, K. Zhong, G.M. Zha, L.F. Wang, Y.L. Wang, W.F. Lu, Y.Y. Wang and G.Y. Yang
Interkeukin-8 (IL-8) is an important inflammatory mediator. It is an angiogenic factor associated with inflammation and carcinogenesis. To date, research on IL-8 has been limited to its role as an indicator of inflammation. There has been no systematic research concerning IL-8 expression levels in the mouse mammary gland durin.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.9.10
- DOI:
- 10.4238/2012.October.9.10
Genetic diversity of central and peripheral populations of Toona ciliata var. pubescens, an endangered tree species endemic to China
Authors: J. Liu, J.M. Jiang and Y.T. Chen
Our objective was to examine the genetic diversity of central and peripheral populations of Toona ciliata var. pubescens, to elucidate whether the central-peripheral hypothesis applies to these populations. We analyzed 392 individuals from nine natural populations using eight pairs of polymorphic SSR primers. The results showe.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.17.10
- DOI:
- http://dx.doi.org/10.4238/2014.June.17.10
Contrasting genetic diversity and differentiation of populations of two successional stages in a neotropical pioneer tree (Eremanthus erythropappus, Asteraceae)
Authors: V.L.O. Freitas, J.P. Lemos-Filho and M.B. Lovato
Eremanthus erythropappus, commonly known as “candeia”,is an abundant pioneer tree species, forming dense populations known as “candeial”, but it is also found in forests at middle stages of succession. Trees from forests are bigger and occur in lower density than in the “candeial”. The objec.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr429
- DOI:
- 10.4238/vol7-2gmr429
miR-146a and miR-196a2 polymorphisms in ovarian cancer risk
Authors: X.C. Sun, A.C. Zhang, L.L. Tong, K. Wang, X. Wang, Z.Q. Sun and H.Y. Zhang
We investigated the relationship between miR-146a and miR-196a2 genetic polymorphisms and development of ovarian cancer in a Chinese population. A total of 134 patients and 227 control subjects were involved in our study between January 2012 and October 2014 from China-Japan Union Hospital of Jilin University. Genotyping of mi.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038468
- DOI:
- 10.4238/gmr.15038468
Food assimilated by two sympatric populations of the brown planthopper Nilaparvata lugens (Delphacidae) feeding on different host plants contaminates insect DNA detected by RAPD-PCR analysis
Authors: M.A. Latif, M.Y. Omar, S.G. Tan, S.S. Siraj, M.E. Ali and M.Y. Rafii
Contamination of insect DNA for RAPD-PCR analysis can be a problem because many primers are non-specific and DNA from parasites or gut contents may be simultaneously extracted along with that of the insect. We measured the quantity of food ingested and assimilated by two sympatric populations of brown planthopper (BPH), Nilapa.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.January.9.4
- DOI:
- http://dx.doi.org/10.4238/2012.January.9.4
DNA barcoding reveals high levels of genetic diversity in the fishes of the Itapecuru Basin in Maranh�£o, Brazil
Authors: M.H.S. Nascimento, M.S. Almeida, M.N.S. Veira, D. Limeira Filho, R.C. Lima, M.C. Barros and E.C. Fraga
DNA barcoding is a useful complementary tool for use in traditional taxonomic studies due to its ability to detect cryptic species, and may be particularly efficient in the identification of fish species. The fish fauna of the Itapecuru River represents an important fishery resource in the Brazilian State of Maranhão, a.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038476
- DOI:
- 10.4238/gmr.15038476
Expression of Rap1GAP in human myeloid disease following microarray selection
Authors: X. Qi, Z. Chen, J. Qian, J. Cen and M. Gu
To find the underlying causes of primary myelodysplastic syndrome (MDS), the gene expression profiling of both CD34+ cells and bone marrow mononuclear cells from MDS patients was performed using oligonucleotide microarray and cDNA microarrays, respectively. Several candidate genes which were differentially expressed in MDS pat.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr395
- DOI:
- 10.4238/vol7-2gmr395
Molecular characterization, expression, and functional analysis of NOD1 in Qingyuan partridge chicken
Authors: Z.Y. Tao, C.H. Zhu, Z.H. Shi, C. Song, W.J. Xu, W.T. Song, J.M. Zou and A.J. Qin
Nucleotide-binding oligomerization domain-containing protein-1 (NOD1) is a cytoplasmic pattern recognition receptor (PRR) and a key member of the NOD-like receptor (NLR) family. It has been reported that NLRs recognize a variety of microbial infections to induce the host innate immune response via modulation of NF-κB signaling. However, no reports o.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.29
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.29
MicroRNA variants and colorectal cancer risk: a meta-analysis
Authors: X.M. Pan, X. Xiao, H.J. Qin, Z. Zhang, Z.H. Li, L.B. Gao and J. Jia
Colorectal cancer (CRC) is a multi-factorial disease, and genetic background may contribute to its etiology. Single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) may be used as specific markers of predisposition for CRC diagnosis and preventionIn this review, we summarize and discuss recent publications evaluating the .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038478
- DOI:
- 10.4238/gmr.15038478
Bayesian inference to study genetic control of resistance to gray leaf spot in maize
Authors: M. Balestre, R.G. Von Pinho, A.H. Brito
Gray leaf spot (GLS) is a major maize disease in Brazil that significantly affects grain production. We used Bayesian inference to investigate the nature and magnitude of gene effects related to GLS resistance by evaluation of contrasting lines and segregating populations. The experiment was arranged in a randomized block desi.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.January.9.3
- DOI:
- http://dx.doi.org/10.4238/2012.January.9.3