Development and characterization of polymorphic microsatellite markers for Castanopsis hystrix (Fagaceae)
Authors: Y. Jiang, Z.H. Li, J.Y. Zhu and H.L. Liu
Castanopsis hystrix is one of the most important and dominant species in evergreen broad-leaved forests in subtropical China. However, the population of this species undergone severe decline because of deforestation over the past 2 decades. For both conservation and forestry management, it is essential to develop molecular markers for C. hystrix. We ident.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.1
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.1
Effect of ethyl methyl sulfonate concentration and different treatment conditions on germination and seedling growth of the cucumber cultivar Chinese long (9930)
Authors: S.N.M. Shah, Z.-H. Gong, M.H. Arisha, A. Khan and S.-L. Tian
We attempted to create a new germplasm of cucumber cultivar Chinese long (9930) using different doses of ethyl methyl sulfonate (EMS) to induce variability. We tested EMS concentration (0, 0.5, 1.0, 1.5, 2, 3% v/v) with post-treatment (0.1 M Na2S2O3 and water), EMS concentration (0, 0.5, 1.0, 1.5% v/v) over different treatment times (8, 16, 24 h), and EMS.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.2
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.2
Inhibitor of signal transducer and activator of transcription 3 (STAT3) suppresses ovarian cancer growth, migration and invasion and enhances the effect of cisplatin in vitro
Authors: Y.J. Tang, Z.L. Sun, W.G. Wu, J. Xing, Y.F. He, D.M. Xin and P. Han
The aim of the present study was to investigate the anti-ovarian cancer effect of the inhibitor of signal transducer and activator of transcription 3 (STAT3), WP1066. Western blot was used to detect the phosphorylation of STAT3 in ovarian cancer cell line SKOV3 and cisplatin-resistant ovarian cancer cell line SKOV3/DDP. MTT and colony-forming assays were .. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.3
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.3
The effect of simulated censored data on estimates of heritability of longevity in the Thoroughbred racing industry
Authors: Eleanor M. Burns, Richard M. Enns and Dorian J. Garrick
We examined the impact of censored data on estimates of heritability of longevity. Longevity, defined as the length of productive racing life of an individual, is influenced by many factors. A simulated data set, modelled on the Irish Thoroughbred industry, was used to estimate heritabilities of longevity. Several scenarios re.. Read More»
- Genet. Mol. Res. 5(1):
Analysis of Fcgrt gene polymorphism in indigenous Chinese sheep and its association with colostrum IgG concentration
Authors: Z.H. Tian, F. Shi, F.G. Zhong, D.P. Bai and X.Y. Zhang
The neonatal Fc receptor (FcRn) plays an important role in regulating IgG homeostasis in the body and passive protection to the offspring. Changes in FcRn expression levels caused by genetic polymorphisms of Fcgrt, which encodes FcRn, may lead to inter-individual differences in colostrum IgG levels in sheep. In this study, we sequenced the FcRn partial he.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.4
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.4
Increase in mitochondrial DNA quantity and impairment of oxidative phosphorylation in bovine fibroblast cells treated with ethidium bromide for 15 passages in culture
Authors: Marcos Roberto Chiaratti and Fl�¡vio Vieira Meirelles
Bovine fetal fibroblast cells were treated with ethidium bromide at a low concentration for 15 passages in culture to determine its effect on mitochondrial DNA copy number and on cell metabolism. Mitochondrial membrane potential and lactate production were estimated in order to characterize cell metabolism. In addition, mitoch.. Read More»
- Genet. Mol. Res. 5(1):
Gly71Arg UGT1A1 polymorphism is associated with breast cancer susceptibility in Han Chinese women
Authors: J. Shi, L.H. Li, X.Y. Duan, Q. Liu, L.L. Sun and Y.T. Tian
Breast cancer is among the most common causes of cancer-related death in women worldwide. Previous studies have demonstrated an association between prolonged estrogen exposure and increased risk of breast cancer. Uridine 5'-diphospho-glucuronosyltransferase 1-1 (UGT1A1) plays a significant role in the detoxification of estrogens. Two major genetic polymor.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038332
- DOI:
- 10.4238/gmr.15038332
cDNA cloning, characterization, and pharmacologic evaluation of anticancer activity of a lectin gene in Pinellia integrifolia
Authors: L.L. Liu, Z.J. Yang and Z.S. Peng
Plant lectins are proteins that possess at least one non-catalytic domain, which could reversibly bind to specific monosaccharides or oligosaccharides. The important roles played by plant lectins in immune regulation, signaling pathways, and plant defense could be attributed to their specific binding activities with carbohydrates. In this study, a Pinelli.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038516
- DOI:
- 10.4238/gmr.15038516
Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China
Authors: J. Yu, Y. Wang, L. Peng, M. Ru and Z.S. Liang
Eucommia ulmoides Oliver, one of the tertiary relict species found only in China, is the only extant species of Eucommiaceae. Using inter-simple sequence repeat (ISSR) and sequence-related amplified polymorphism (SRAP) markers, we studied the genetic diversity and population genetic structure of 187 accessions from 17 E. ulmoides populations throughout it.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.5
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.5
Performance of genomic data sets on the estimation of the divergence time of New World and Old World anthropoids
Authors: C.G. Schrago and C.M. Voloch
The origin of New World anthropoids has received renewed attention since the advent of molecular dating methods that relax the assumption of a strict molecular clock. However, the studies conducted to date have estimated the time of the separation of New World and Old World anthropoids at values as different as 70 and 22 Ma. W.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.1
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.1