A comparative analysis of highly conserved sex-determining genes between Apis mellifera and Drosophila melanogaster
Authors: Alexandre S. Cristino, Adriana Mendes do Nascimento, Luciano da Fontoura Costa and Zil�¡ Luz Paulino Sim�µes
A comparison of the most conserved sex-determining genes between the fruit fly, Drosophila melanogaster, and the honey bee, Apis mellifera, was performed with bioinformatics tools developed for computational molecular biology. An initial set of protein sequences already described in the fruit fly as participants of the sex-det.. Read More»
- Genet. Mol. Res. 5(1):
Pharmacogenetic role of XRCC1 polymorphisms on the clinical outcome of gastric cancer patients with platinum-based chemotherapy: a systematic review and meta-analysis
Authors: J. Xu, J. Ma, H.T. Zong, S.Y. Wang and J.W. Zhou
It is still controversial whether X-ray repair cross-complementing group (XRCC1) gene polymorphisms (Arg194Trp and Arg399Gln) are associated with the clinical outcome of platinum-based chemotherapy in gastric cancer patients based on published studies. Meta-analysis was performed to provide a systematic review of the findings... Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.2
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.2
New strategy to detect single nucleotide polymorphisms
Authors: Miguel Galves, Jos�© Augusto Amgarten Quitzau and Zanoni Dias
A great effort has been made to identify and map a large set of single nucleotide polymorphisms. The goal is to determine human DNA variants that contribute most significantly to population variation in each trait. Different algorithms and software packages, such as PolyBayes and PolyPhred, have been developed to address this .. Read More»
- Genet. Mol. Res. 5(1):
Conservation implications of the genetic diversity of Gymnospermium microrrhynchum in Korea
Authors: S.H. Lee, M.H. Yeon and J.K. Shim
Gymnospermium microrrhynchum (Berberidaceae) is an ephemeral perennial herb with a limited distributional range in the Baekdudaegan mountain areas of the Korean Peninsula, and is designated a rare plant by the Korean Forest Service. Information about its genetic variation and structure is important for developing successful co.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048843
- DOI:
- 10.4238/gmr15048843
BayBoots: a model-free Bayesian tool to identify class markers from gene expression data
Authors: Ricardo Z.N. V�ªncio, Diogo F.C. Patr�£o, Cassio S. Baptista, Carlos A.B. Pereira and Bianca Zingales
One of the goals of gene expression experiments is the identification of differentially expressed genes among populations that could be used as markers. For this purpose, we implemented a modelfree Bayesian approach in a user-friendly and freely available web-based tool called BayBoots. In spite of a common misunderstanding th.. Read More»
- Genet. Mol. Res. 5(1):
Genetic characterization and authentication of Dimocarpus longan Lour. using an improved RAPD technique
Authors: Z.Q. Mei, S.Y. Fu, H.Q. Yu1, L.Q. Yang, C.G. Duan, X.Y. Liu, S. Gong1 and J.J. Fu
Dimocarpus longan Lour. is an edible and traditional herb in China, commonly referred to as longon. An improved randomly amplified polymorphic DNA (RAPD) protocol was here developed in order to determine the geographical origins of D. longan samples collected from 5 provinces in the southern and southwestern areas of China, in.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.3
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.3
Environmental variations drive polyploid evolution in neotropical Eugenia species (Myrtaceae)
Authors: R.M. Silveira, R.M. Machado, E.R. Forni-Martins, C.F. Verola and I.R. Costa
Polyploidy is one of the most important mechanisms of speciation and diversification in plant evolution. Polyploidy results in genetic variation among individuals of the same species and even between populations, and may be responsible for differences in environmental tolerance between populations of the same species. This stu.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048842
- DOI:
- 10.4238/gmr15048842
Building multiple sequence alignments with a flavor of HSSP alignments
Authors: Roberto Hiroshi Higa, Sergio Aparecido Braga da Cruz, Paula Regina Kuser, Michel Eduardo Beleza Yamagishi, Renato Fileto, Stanley Robson de Medeiros Oliveira, Ivan Mazoni, Edgard Henrique dos Santos, Adauto Luiz Mancini and Goran Neshich
Homology-derived secondary structure of proteins (HSSP) is a well-known database of multiple sequence alignments (MSAs) which merges information of protein sequences and their threedimensional structures. It is available for all proteins whose structure is deposited in the PDB. It is also used by STING and JavaProtein Dossier .. Read More»
- Genet. Mol. Res. 5(1):
Genetic structure of the threatened Dipterocarpus costatus populations in lowland tropical rainforests of southern Vietnam
Authors: N.M. Duc, V.D. Duy, B.T.T. Xuan, B.V. Thang, N.T.H. Ha and N.M. Tam
Dipterocarpus costatus is an endangered species restricted to the lowland forests of southern Vietnam. Habitat loss and over-exploitation of D. costatus wood are the major threats to this species. We investigated the level of genetic variability within and among populations of D. costatus in order to provide guidelines for the.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048821
- DOI:
- 10.4238/gmr15048821
GenoMycDB: a database for comparative analysis of mycobacterial genes and genomes
Authors: Marcos Catanho, Daniel Mascarenhas, Wim Degrave and Antonio BasÃ?Âlio de Miranda
Several databases and computational tools have been created with the aim of organizing, integrating and analyzing the wealth of information generated by large-scale sequencing projects of mycobacterial genomes and those of other organisms. However, with very few exceptions, these databases and tools do not allow for massive an.. Read More»
- Genet. Mol. Res. 5(1):