Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility
Authors: S.-S. Li, J. Li, Z. Xiao, A.-G. Ren and L. Jin
The aim of this study was to explore the relationship between 2 genetic polymorphisms of the methylenetetrahydrofolate reductase gene (MTHFR), C677T and A1298C, and determine the long-term reproductive outcome in infertile men. This was a prospective study conducted in an andrology clinic. Men with a 1-year history of.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.24.26
- DOI:
- 10.4238/2014.March.24.26
Efficacy and safety of nucleoside analogues in preventing vertical transmission of the hepatitis B virus from father to infant
Authors: L.-H. Cao,P.-L. Zhao,Z.-M. Liu,S.-C. Sun,D.-B. Xu,J.-D. Zhang,Z.-H. Shao
We examined the efficacy and safety of nucleoside analogues in preventing the vertical transmission of hepatitis B virus (HBV) from father to infant. We included 201 patients who visited the liver clinic of our hospital. The patients were positive for HBV surface antigen (HBsAg), HBeAg, anti-HBc, and HBV DNA; 189 patients (94%.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.4
- DOI:
- 10.4238/2015.December.1.4
Complete asynapsis resulting in 2n pollen formation in Paspalum jesuiticum Parodi (Poaceae)
Authors: R.A. Bernardo Filho, A.C.C. Santos, F.H.D. Souza, J.F.M. Valls and M.S. Pagliarini
Cytological investigation revealed complete asynapsis during microsporogenesis in 2 wild accessions of Paspalum jesuiticum collected in distinct Brazilian regions. Both accessions were hexaploid (2n = 6x = 60) and 60 univalents could be counted at diakinesis. In this phase, the majority of meiocytes exhibited univalents with b.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.17.9
- DOI:
- 10.4238/2014.January.17.9
Improvement in the carcass traits and meat quality of growing-finishing Rongchang pigs by conjugated linoleic acid through altered gene expression of muscle fiber types
Authors: J.X. Huang, R.L. Qi, X.L. Chen, X.Y. You, X.Q. Liu, F.Y. Yang and Z.H. Liu
A total of 160 Rongchang pigs (26.76 ± 1.78 kg) were randomly assigned to 5 dietary treatment groups until their body weight (BW) reached 90 kg. The diets were supplemented with 0, 0.5, 1.0, 1.5, and 2.0% conjugated linoleic acid (CLA). Our results showed that the 1.0 to 2.0% CLA-fed pigs had less back fat deposition wh.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.24.25
- DOI:
- 10.4238/2014.March.24.25
Novel non-synonymous polymorphisms in the COX-1 gene in Turkish pediatric patients with cardiovascular anomalies
Authors: Coskun, Y. Colkesen, F. Ayik A. Berdeli and Y. Atay
Variation in the gene encoding cyclooxygenase-1 (COX-1) is involved in the process of aspirin resistance. This study investigated the genetic variations in the COX-1 gene. The 4 coding regions of the human COX-1 gene in 90 pediatric patients (median age of 6.5 months, 55% males) with cardiovascular anomalies were screened using DNA sequencing. Twenty codi.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.17.10
- DOI:
- 10.4238/2014.January.17.10
Association analysis between the OPG g.27667T>A genetic variant and bone mineral density in Chinese postmenopausal women
Authors: J.J. Zhao, D.H. Feng, L. Cheng, T. Lu and L. Wang
The purpose of this study was to investigate the association of the g.27667T>A genetic variant in the osteoprotegerin (OPG) gene with bone mineral density (BMD) and osteoporosis. A total of 393 primary osteoporosis subjects and 402 healthy controls were recruited. The BMD of the femoral neck hip, lumbar spine (L2-4.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.24.16
- DOI:
- 10.4238/2014.March.24.16
Polymorphism of the inhibin �²A gene and its relationship with superovulation traits in Chinese Holstein cows
Authors: W.C. Yang, S.J. Li, L. Chen and L.G. Yang
Inhibin is a major regulator of secretion of follicle-stimulating hormone, which is involved in follicular development and regulation of steroidogenesis in females. The objectives of this study were to detect polymorphisms of the bovine inhibin beta-A subunit (INHβA) gene and to evaluate its associations with superovulato.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.17.11
- DOI:
- 10.4238/2014.January.17.11
Development and characterization of novel SSR markers in Siniperca kneri Garman
Authors: M. Yang, H.Z. Zheng, X.-F. Liang, C.X. Tian, Y.Q. Dou, K.C. Zhu and Y.C. Yuan
In this study, 37 transcriptome-derived simple sequence repeat (SSR) markers and 18 genomic SSR markers were developed and characterized in the Chinese perch, Siniperca kneri Garman. The average allele number per locus was 5.1 (range: 2-8) for transcriptome-derived SSRs and 3.8 (range: 2-5) for genomic SSRs. The avera.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.24.18
- DOI:
- 10.4238/2014.March.24.18
Stability and adaptability of grain sorghum hybrids in the off-season
Authors: J.E. Almeida Filho, F.D. Tardin, R.F. Daher, T.C. Barb�©, C.M. Paula, M.J. Cardoso and V.P.C. Godinho
We analyzed productivity data obtained from experiments on grain sorghum conducted in 7 locations of its cultivation in Brazil. A total of 25 hybrids were analyzed, of which 22 were pre-commercial and 3 were cultivars. The Wricke and Purchase et al. methods were highly consistent in identifying individuals with low contributio.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.24.24
- DOI:
- 10.4238/2014.March.24.24
Microsatellite markers for the Cabre�ºva tree, Myroxylon peruiferum (Fabaceae), an endangered medicinal species from the Brazilian Atlantic Forest
Authors: K.D. Schwarcz, M.M. Bajay, C.M.T. Macrini, V.L.P. Salazar, A.P. Souza, J.B. Pinheiro, P.H.S. Brancalion, R.R. Rodrigues and M.I. Zucchi
The Cabreúva tree, Myroxylon peruiferum, is an endangered tropical species from Brazil used in forest restoration projects. It is known for its medicinal properties. Eleven microsatellite markers were developed for this species, from a microsatellite-enriched library. Nine of these markers, characterized in 30 .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.26.1
- DOI:
- 10.4238/2014.March.26.1